MILabs wins WMIC Innovation of the Year 2018

 

The use of replication-competent viruses as oncolytic agents is rapidly expanding, with several oncolytic viruses approved for cancer therapy. However, as responses to therapy are highly variable, understanding the dynamics of therapy is critical for optimal application of virotherapy in practice. In this paper with the running title “Quantitative imaging of oncolytic viruses”, researchers at the Mayo Clinic use a SPECT/CT to address a fundamental gap in our knowledge of oncolytic virotherapy by presenting technology that gives insight into the behavior of oncolytic viruses in vivo. Read more here:

 

 

Fibrogenesis is the underlying mechanism of wound healing and repair. Mayo Clinic researchers generated transgenic reporter rats expressing the sodium iodide symporter (NIS) driven by the rat collagen type-1 alpha-1 (Col1α1) promoter and demonstrated that fibrogenesis can be visualized over time using nuclear imaging following activation of NIS expression. Nuclear imaging of NIS reporter rats would facilitate studies in physiological wound repair and pathological processes such as fibrosis and the development of anti-fibrotic drugs. Read more here:

 

EANM, October 13 – 17, 2018, Düsseldorf, Germany
PNI, November 12, 2018, London, United Kingdom
IEEE NSS-MIC, November 10 – 17, 2018 Sydney, Australia
EMIM, March 19 – 22, 2019, Glasgow, United Kingdom
ISRS, May 26 – 31, 2019, Beijing, China