The World Molecular Imaging Congress (WMIC) has named MILabs’ VECTor6 imaging system with Broadband Photon Tomography technique, the recipient of its Commercial Innovation of the Year award. Among the many benefits brought about by Broadband Photon Tomography is omni-tomography – the ability to obtain images from various tracers with both spatial and temporal co-registration. More specifically:
PET at 0.55 mm 18F resolution, positron range-free imaging for isotopes such as 124I, 76Br, and 82Rb, and simultaneous multi-isotope PET and PET/SPECT acquisitions.
SPECT at 0.25 mm in vivo resolution and 140 micronex vivo for automated 3D autoradiography without tissue slicing.
Radiotherapy imaging with alpha- and beta-emitting isotopes, simultaneously acquired with images from PET and SPECT tracers if needed.
Optical imaging in 2D and 3D with bioluminescence and fluorescence, and with CT attenuation correction for quantitative in vivo distribution of optical probes in mice.
CT with best-in-class low-dose & high-resolution in-vivo acquisitions from mice to rabbits. With dual-gated dynamic acquisitions, DCE with dual energy imaging, etc.
Innovative use of MILabs’ SPECT/CT for NIS reporter imaging at the Mayo Clinic
In vivo estimation of oncolytic virus populations within tumors. D. Dingli, M-Y. Jung, C. P. Offord, et al. Cancer Research, August 2018.
The use of replication-competent viruses as oncolytic agents is rapidly expanding, with several oncolytic viruses approved for cancer therapy. However, as responses to therapy are highly variable, understanding the dynamics of therapy is critical for optimal application of virotherapy in practice. In this paper with the running title “Quantitative imaging of oncolytic viruses”, researchers at the Mayo Clinic use a SPECT/CT to address a fundamental gap in our knowledge of oncolytic virotherapy by presenting technology that gives insight into the behavior of oncolytic viruses in vivo. Read more here:
Transgenic NIS reporter rats for tracking of fibrogenesis. B. Brunton, L. Suksanpaisan, H. Li, et al. Scientific Reports, September 2018.
Fibrogenesis is the underlying mechanism of wound healing and repair. Mayo Clinic researchers generated transgenic reporter rats expressing the sodium iodide symporter (NIS) driven by the rat collagen type-1 alpha-1 (Col1α1) promoter and demonstrated that fibrogenesis can be visualized over time using nuclear imaging following activation of NIS expression. Nuclear imaging of NIS reporter rats would facilitate studies in physiological wound repair and pathological processes such as fibrosis and the development of anti-fibrotic drugs. Read more here:
For a more comprehensive list of user publications, view the MILabs Scientific Library here.
Meet us at:
EANM, October 13 – 17, 2018, Düsseldorf, Germany
PNI, November 12, 2018, London, United Kingdom
IEEE NSS-MIC, November 10 – 17, 2018 Sydney, Australia
EMIM, March 19 – 22, 2019, Glasgow, United Kingdom ISRS, May 26 – 31, 2019, Beijing, China