Selected journal papers
Exciting applications of MILabs imaging equipment
2024
A nanoemulsion targeting adipose hypertrophy and hyperplasia shows anti-obesity efficiency in female mice.
Initial IL-10 production dominates the therapy of mesenchymal stem cell scaffold in spinal cord injury.
Inhibiting Lysyl Oxidases prevents pathologic cartilage calcification.
Microbiota modulation by dietary beta-glucan prevents steatotic liver disease progression.
Preclinical Evaluation of Minigastrin Analogs and Proof-of-Concept [ 68 Ga]Ga-DOTA-CCK-66 PET/CT in 2 Patients with Medullary Thyroid Cancer.
Remineralizing effects of hydroxypropyl methylcellulose film-loaded amorphous calcium phosphate nanoprecursors on enamel artificial caries lesions.
Low cost, high temporal resolution optical fiber-based γ-photon sensor for real-time pre-clinical evaluation of cancer-targeting radiopharmaceuticals.
A novel simplified approach for endodontic retrograde surgery in short single-rooted teeth.
ADAMTSL2 mutations determine the phenotypic severity in Geleophysic Dysplasia.
T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors.
A new ex vivo human model of osteoarthritis cartilage calcification.
Surface-activated 3D-printed PEEK implant enhances anti-infection and osteogenesis.
Effectiveness of [67Cu]Cu-trastuzumab as a theranostic against HER2-positive breast cancer.
Novel sheep model to assess critical-sized bone regeneration with periosteum for in-vivo bioreactors.
Biodistribution of Radioactively Labeled Splice Modulating Antisense Oligonucleotides After Intracerebroventricular and Intrathecal Injection in Mice.
Development of Small HN Linked Radionuclide Iodine-125 for Nanocarrier Image Tracing in Mouse Model.
From breast cancer cell homing to the onset of early bone metastasis: The role of bone (re)modeling in early lesion formation.
Immunomodulatory Prodrug Micelles Imitate Mild Heat Effects to Reshape Tumor Microenvironment for Enhanced Cancer Immunotherapy.
Efficacy of [67Cu]Cu-EB-TATE Theranostic Against Somatostatin Receptor Subtype-2–Positive Neuroendocrine Tumors.
2023
Preventing acute lung injury from progressing to pulmonary fibrosis by maintaining ERS homeostasis through a multistage targeting nanomicelle.
Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake.
Synthesis and preclinical evaluation of novel 99mTc-labeled PSMA ligands for radioguided surgery of prostate cancer.
EGFL7 Secreted By Human Bone Mesenchymal Stem Cells Promotes Osteoblast Differentiation Partly Via Downregulation Of Notch1-Hes1 Signaling Pathway.
Enhanced Cancer Imaging and Chemo-Photothermal Combination Therapy by Cancer-Targeting Bismuth-Based Nanoparticles.
Targeting Ligand Independent Tropism of siRNA-LNP by Small Molecules for Directed Therapy of Liver or Myeloid Immune Cells.
Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles.
A clinically translatable kit for MRI/NMI dual-modality nanoprobes based on anchoring group-mediated radiolabeling.
Doped Graphene To Mimic the Bacterial NADH Oxidase for One-Step NAD+ Supplementation in Mammals.
A radioiodinated rucaparib analogue as an Auger electron emitter for cancer therapy.
Safety, Biodistribution, and Dosimetry Study of Meplazumab, a Potential COVID-19 Therapeutic Drug, with 131 I-Labeling and SPECT Imaging.
Towards Standardisation of a Diffuse Midline Glioma Patient-Derived Xenograft Mouse Model Based on Suspension Matrices for Preclinical Research.
Effects of an orthodontic primer containing amorphous fluorinated calcium phosphate nanoparticles on enamel white spot lesions.
Novel Biomaterial-Binding/Osteogenic Bi-Functional Peptide Binds to Silk Fibroin Membranes to Effectively Induce Osteogenesis In Vitro and In Vivo.
A SPECT-based method for dynamic imaging of the glymphatic system in rats.
Estimating Crestal Thickness of Alveolar Bones on Intra-oral Ultrasonograms.
Evaluating the Targeting of a Staphylococcus-aureus-Infected Implant with a Radiolabeled Antibody In Vivo.
Effects of a calcium/vitamin D/Zinc combination on anti-osteoporosis in ovariectomized rats.
Effect of Cellular and Microenvironmental Multidrug Resistance on Tumor-Targeted Drug Delivery in Triple-Negative Breast cancer.
Polydopamine-Coated Radiolabeled Microspheres for Combinatorial Radioembolization and Photothermal Cancer Therapy.
Evaluation of [99mTc]Tc-TTHMP as a SPECT imaging agent for skeletal system.
Development of the First 18F-Labeled Radiohybrid-Based Minigastrin Derivative with High Target Affinity and Tumor Accumulation by Substitution of the Chelating Moiety.
Radioimmune Imaging of α4β7 Integrin and TNFα; for Diagnostic and Therapeutic Applications in Inflammatory Bowel Disease.
Intrafibrillar mineralization and immunomodulatory for synergetic enhancement of bone regeneration via calcium phosphate nanocluster scaffold.
Quantitative Imaging of Hypoxic CAIX-Positive Tumor Areas with Low Immune Cell Infiltration in Syngeneic Mouse Tumor Models.
Imaging DNA damage response by γH2AX in vivo predicts treatment response to Lutetium-177 radioligand therapy and suggests senescence as a therapeutically desirable outcome.
Quantitative Evaluation of a Multimodal Aptamer-Targeted Long-Circulating Polymer for Tumor Targeting.
Potential of an Aligned Porous Hydrogel Scaffold Combined with Periodontal Ligament Stem Cells or Gingival Mesenchymal Stem Cells to Promote Tissue Regeneration in Rat Periodontal Defects.
Sustained Delivery of a Heterodimer Bone Morphogenetic Protein-2/7 via a Collagen Hydroxyapatite Scaffold Accelerates and Improves Critical Femoral Defect Healing.
Pre- and Intraoperative Visualization of GRPR-Expressing Solid Tumors: Preclinical Profiling of Novel Dual-Modality Probes for Nuclear and Fluorescence Imaging.
Preclinical Evaluation of [155/161Tb]Tb-Crown-TATE - A Novel SPECT Imaging Theranostic Agent Targeting Neuroendocrine Tumours.
Radiosensitisation by olaparib through focused ultrasound delivery in a diffuse midline glioma model.
Xenorhinos bhatnagari sp. nov., a new, nasal-emitting trident bat (Rhinonycteridae, Rhinolophoidea) from early Miocene forests in northern Australia.
Neutrophil hitchhiking for drug delivery to the bone marrow.
Spatiotemporal tracking of gold nanorods after intranasal administration for brain targeting.
Biparatopic anti-HER2 drug radioconjugates as breast cancer theranostics.
Preclinical Evaluation of a PSMA-Targeting Homodimer with an Optimized Linker for Imaging of Prostate Cancer.
Chitosan-calcium carbonate scaffold with high mineral content and hierarchical structure for bone regeneration.
Ultraviolet Light-Based Micropattern Printing on Titanium Surfaces to Promote Early Osseointegration.
Partial decellularization eliminates immunogenicity in tracheal allografts.
LAMP2A regulates the balance of mesenchymal stem cell adipo-osteogenesis via the Wnt/β-catenin/GSK3β signaling pathway.
Chicken HOXC8 and HOXC10 genes may play a role in the altered skull morphology associated with the Crest phenotype.
Bestatin as a treatment modality in experimental periodontitis.
Assessment of Transarterial Chemoembolization Using Super-resolution Ultrasound Imaging and a Rat Model of Hepatocellular Carcinoma.
Radionuclide-Labeled Microspheres for Radio-immunotherapy of Hepatocellular Carcinoma.
Fibroblast Activation Protein-Targeting Minibody-IRDye700DX for Ablation of the Cancer-Associated Fibroblast with Photodynamic Therapy.
Customized Bioceramic Scaffolds and Metal Meshes for Challenging Large-size Mandibular Bone Defect Regeneration and Repair.
A Model Study to Evaluate Osseointegration and Fracture Healing Following Open Reduction and Internal Fixation (ORIF) in Diabetic Lewis Rats.
Reduction of Tumor Growth with RNA-Targeting Treatment of the NAB2–STAT6 Fusion Transcript in Solitary Fibrous Tumor Models.
Loricrin and Cytokeratin Disorganisation in Severe Forms of Periodontitis.
Liposome-anchored mesenchymal stem cells for radiation pneumonia/fibrosis treatment.
Radiochemical and Biological Evaluation of 3p-C-NETA-ePSMA-16, a Promising PSMA-Targeting Agent for Radiotheranostics.
Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design.
Running exercise with and without calcium supplementation from tuna bone reduced bone impairment caused by low calcium intake in young adult rats.
Benidipine-loaded nanoflower-like magnesium silicate improves bone regeneration.
Direct In Vivo Activation of T Cells with Nanosized Immunofilaments Inhibits Tumor Growth and Metastasis.
GuiLu-ErXian Glue extract promotes mesenchymal stem cells (MSC)-Induced chondrogenesis via exosomes release and delays aging in the MSC senescence process.
Nerve terminals in the tumor microenvironment as targets for local infiltration analgesia.
Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus.
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice.
Intermittent Fasting Primes the Tumor Microenvironment And Improves Nanomedicine Delivery In Hepatocellular Carcinoma.
[212Pb]Pb-eSOMA-01: A Promising Radioligand for Targeted Alpha Therapy of Neuroendocrine Tumors.
Reactive astrocytes mediate TSPO overexpression in response to sustained CNTF exposure in the rat striatum.
Zein-based nanospheres and nanocapsules for the encapsulation and oral delivery of quercetin.
Repurposing Tamoxifen for Tumor Microenvironment Priming and Enhanced Tumor-Targeted Drug Delivery.
Smoking and tetramer tryptase accelerate intervertebral disc degeneration by inducing METTL14-mediated DIXDC1 m6 modification.
Downregulation of Yap1 during limb regeneration results in defective bone formation in axolotl.
Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool.
Fibroblast Activation Protein-Targeted Photodynamic Therapy of Cancer-Associated Fibroblasts in Murine Models for Pancreatic Ductal Adenocarcinoma.
Synthesis and Evaluation of ePSMA-DM1: A New Theranostic Small-Molecule Drug Conjugate (T-SMDC) for Prostate Cancer.
A Theranostic Approach to Imaging and Treating Melanoma with 203Pb/212Pb-Labeled Antibody Targeting Melanin.
Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size.
Gliadin nanoparticles for oral administration of bioactives: Ex vivo and in vivo investigations.
Development of hybrid scaffolds with biodegradable polymer composites and bioactive hydrogels for bone tissue engineering.
Power Benefits of High-Altitude Flapping Wing Flight at the Monarch Butterfly Scale.
Effects of N-acetyl-L-cysteine polysulfides on periodontitis in a mouse model.
Side-by-side comparison of the two widely studied GRPR radiotracers, radiolabeled NeoB and RM2, in a preclinical setting.
An injectable photopolymerizable chitosan hydrogel doped anti-inflammatory peptide for long-lasting periodontal pocket delivery and periodontitis therapy.
IgA antibody immunotherapy targeting GD2 is effective in preclinical neuroblastoma models.
[99mTc]Tc-PentixaTec: development, extensive pre-clinical evaluation, and first human experience.
Assessing the Biocompatibility and Regeneration of Electrospun-Nanofiber Composite Tracheal Grafts.
Imaging of 212Pb in mice with a clinical SPECT/CT.
Repeated Cocaine Intake Differentially Impacts Striatal D2/3 Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral Markers of Drug Abuse.
The Balance Between the Therapeutic Efficacy and Safety of [177Lu]Lu-NeoB in a Preclinical Prostate Cancer Model.
CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis.
Coded aperture and Compton imaging for the development of 225Ac-based radiopharmaceuticals.
Solvent Exchange-Motivated and Tunable in Situ Forming Implants Sustaining Triamcinolone Acetonide Release for Arthritis Treatment.
Magnetic Nanofibrous Hydrogels for Dynamic Control of Stem Cell Differentiation.
Breast stiffness, a risk factor for cancer and the role of radiology for diagnosis.
[123I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer.
Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT.
Rearmed Bifunctional Chelating Ligand for 225Ac/155Tb Precision-Guided Theranostic Radiopharmaceuticals─H4noneunpaX.
Ferritin was involved in interleukin-17A enhanced osteogenesis through autophagy activation.
Efficient intervention for pulmonary fibrosis via mitochondrial transfer promoted by mitochondrial biogenesis.
Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury.
MULTI-RADIONUCLIDE IN VIVO IMAGING OF SOLID TUMORS IN SMALL LABORATORY ANIMALS
FOR EXPERIMENTAL ONCOLOGY.
TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.
Xenogeneic equine stem cells activate anti-tumor adaptive immunity in a 4T1-based intraductal mouse model for triple-negative breast cancer: proof-of-principle.
Bi-HPDO3A as a novel contrast agent for X-ray computed tomography.
Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine.
In Vivo Prevention of Implant-Associated Infections Caused by Antibiotic-Resistant Bacteria through Biofunctionalization of Additively Manufactured Porous Titanium.
A 50-million-year-old, three-dimensionally preserved bat skull supports an early origin for modern echolocation.
Biomimetic Intrafibrillar Mineralization of Native Tendon for Soft–Hard Interface Integration by Infiltration of Amorphous Calcium Phosphate Precursors.
Longitudinal evaluation of the biodistribution and cellular internalization of the bispecific CD3xTRP1 antibody in syngeneic mouse tumor models.
The GEM-handle as convenient labeling strategy for bimodal single-domain antibody-based tracers carrying 99mTc and a near-infrared fluorescent dye for intra-operative decision-making.
Influence of spill-over for 99mTc images and the effect of scatter correction for dual-isotope simultaneous acquisition with 99mTc and 18F using small-animal SPECT-PET/CT system.
Preclinical Evaluation of a Radiotheranostic Single-Domain Antibody Against Fibroblast Activation Protein α.
CT- and MRI-Aided Fluorescence Tomography Reconstructions for Biodistribution Analysis.
Revolutionizing fracture fixation in diabetic and non-diabetic rats: High mobility group box 1-based coating for enhanced osseointegration.
Myeloid Heterogeneity Mediates Acute Exacerbations of Pulmonary Fibrosis.
Sarsasapogenin inhibits YAP1-dependent chondrocyte ferroptosis to alleviate osteoarthritis.
A Model of Immediate Implant Placement to Evaluate Early Osseointegration in 129/Sv Diabetic Mice.
Antitumor Effect by Either FLASH or Conventional Dose Rate Irradiation Involves Equivalent Immune Responses.
Novel Combination Treatment for Melanoma: FLASH Radiotherapy and Immunotherapy Delivered by a Radiopaque and Radiation Responsive Hydrogel.
Remineralization of Dentin with Cerium Oxide and Its Potential Use for Root Canal Disinfection.
SENTRI: Single-particle Energy Transducer for Radionuclide Injections for Personalized Targeted Radionuclide Cancer Therapy.
2022
Theranostic PSMA ligands with optimized backbones for intraoperative multimodal imaging and photodynamic therapy of prostate cancer.
Towards Complete Tumor Resection: Novel Dual-Modality Probes for Improved Image-Guided Surgery of GRPR-Expressing Prostate Cancer.
Single cell analysis reveals inhibition of angiogenesis attenuates the progression of heterotopic ossification in Mkx−/− mice.
Synthesis and Evaluation of Radioiodine-Labeled pH (Low) Insertion Peptide Variant 7-Like Peptide as a Noninvasive Tumor Microenvironment Imaging Agent in a Mouse MDA-MB-231 Triple-Negative Breast Cancer Model.
Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm.
Deep brain stimulation electrode modeling in rats.
Substitution of L-Trp by α-methyl-L-Trp in 177Lu-RM2 results in 177Lu-AMTG, a high affinity GRPR ligand with improved in vivo stability.
Novel VHH-Based Tracers with Variable Plasma Half-Lives for Imaging of CAIX-Expressing Hypoxic Tumor Cells.
Synthesis and Preclinical Evaluation of 177Lu-labeled Radiohybrid PSMA Ligands (rhPSMAs) for Endoradiotherapy of Prostate Cancer.
BMP3 is a novel locus involved in the causality of ocular coloboma.
Metal-ion coordinated self-assembly of human insulin directs kinetics of insulin release as determined by preclinical SPECT/CT imaging.
Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents.
Improved Multimodal Tumor Necrosis Imaging with IRDye800CW-DOTA Conjugated to an Albumin-Binding Domain.
Targeting Refractory Mantle Cell Lymphoma for Imaging and Therapy Using C-X-C Chemokine Receptor Type 4 Radioligands.
Quantitative in vivo micro-computed tomography for monitoring disease activity and treatment response in a collagen-induced arthritis mouse model.
Assessment of mouse-specific pharmacokinetics in kidneys based on 131I activity measurements using micro-SPECT.
[213Bi]Bi 3+ /[111In]In 3+ -neunpa-cycMSH: Theranostic Radiopharmaceutical Targeting Melanoma─Structural, Radiochemical, and Biological Evaluation.
Therapeutic dendritic cell vaccines engineered with antigen-biomineralized Bi2S3 nanoparticles for personalized tumor radioimmunotherapy.
A Micro-computed Tomography Database and Reference Implementation for Parallel Computations of Trabecular Thickness and Spacing.
Customized Reconstruction of Alveolar Cleft by High Mechanically Stable Bioactive Ceramic Scaffolds Fabricated by Digital Light Processing.
Seamless and early gap healing of osteochondral defects by autologous mosaicplasty combined with bioactive supramolecular nanofiber-enabled gelatin methacryloyl (BSN-GelMA) hydrogel.
Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction.
PD-L1 Antibody Pharmacokinetics and Tumor Targeting in Mouse Models for Infectious Diseases.
131I- α PD-L1 immobilized by bacterial cellulose for enhanced radio-immunotherapy of cancer.
Imaging PARP with [18F] rucaparib in pancreatic cancer models.
Radiolabeled Human Protein-Functionalized Upconversion Nanoparticles for Multimodal Cancer Imaging.
SPECT/CT Imaging of 111Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines.
A multimodal imaging workflow for monitoring CAR T cell therapy against solid tumor from whole-body to single-cell level.
Molecular Detection of Venous Thrombosis in Mouse Models Using SPECT / CT.
Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals.
In vivo validation of the switch antibody concept : SPECT / CT imaging of the anti-CD137 switch antibody Sta-MB shows high uptake in tumors but low uptake in normal organs in human CD137 knock-in mice.
A Renal-Clearable Activatable Molecular Probe for Fluoro-Photacoustic and Radioactive Imaging of Cancer Biomarkers.
Ytterbium Nanoparticle Contrast Agents for Conventional and Spectral Photon-Counting CT and Their Applications for Hydrogel Imaging.
Efficient Radiolabeling of Block Copolymer Micelles through Radiometal Salt Precipitation for Theranostic Applications.
Substitution of L-Trp by α-methyl-L-Trp in 177 Lu-RM2 results in 177 Lu-AMTG, a high affinity GRPR ligand with improved in vivo stability.
Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release ☆.
Simultaneous imaging of 68 Ga-DOTA-TATE and 177 Lu-DOTA-TATE in murine models of neuroblastoma.
Radiofluorination of a highly potent ATM inhibitor as a potential PET imaging agent.
SPECT imaging of 226Ac as a theranostic isotope for 225Ac radiopharmaceutical development.
In situ formation of osteochondral interfaces through “bone-ink” printing in tailored microgel suspensions.
The role of Dentin Sialophosphoprotein (DSPP) in craniofacial development.
High-efficient engineering of osteo-callus organoids for rapid bone regeneration within one month.
Cell-Laden Gradient Microgel Suspensions for Spatial Control of Differentiation During Biofabrication.
The influence of foramina on femoral neck fractures and strains predicted with finite element analysis.
Development of root resorption during orthodontic tooth movement after cleft repair using different grafting materials in rats.
Msx1+ stem cells recruited by bioactive tissue engineering graft for bone regeneration.
Biodistribution and toxicity of innate defense regulator 1018 (IDR-1018).
Preclinical evaluation of [18F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection.
Synthesis and Evaluation of Two Long-Acting SSTR2 Antagonists for Radionuclide Therapy of Neuroendocrine Tumors.
Optimization of the Pharmacokinetic Profile of [99mTc]Tc-N4-Bombesin Derivatives by Modification of the Pharmacophoric Gln-Trp Sequence.
H 4 picoopa─Robust Chelate for 225 Ac/ 111 In Theranostics.
SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline.
Encapsulation of Lactobacillus plantarum in casein-chitosan microparticles facilitates the arrival to the colon and develops an immunomodulatory effect.
Development of a novel small-animal myocardial phantom can evaluate the image quality of dual-isotope simultaneous acquisition (DISA).
SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia.
A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions.
Performance evaluation of a preclinical SPECT/CT system for multi-animal and multi-isotope quantitative experiments.
Delivery of aPD-L1 antibody to i.p. tumors via direct penetration by i.p. route: Beyond EPR effect.
TSPO expression in a Zika virus murine infection model as an imaging target for acute infection-induced neuroinflammation.
Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection.
H3TPAN-Triazole-Bn-NH2: Tripicolinate Clicked-Bifunctional Chelate for [225Ac]/[111In] Theranostics.
Exploring the Potential of High-Molar-Activity Samarium-153 for Targeted Radionuclide Therapy with [153Sm]Sm-DOTA-TATE.
Introduction of a SiFA Moiety into the D-Glutamate Chain of DOTA-PP-F11N Results in Radiohybrid-Based CCK-2R-Targeted Compounds with Improved Pharmacokinetics In Vivo.
Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge.
Fibroblast activation protein targeted radioligand therapy for treatment of solid tumors.
Engineering of a Fully Human Anti-MUC-16 Antibody and Evaluation as a PET Imaging Agent.
Micro-CT Analysis of Implanted Poly-Ether-Ether-Ketone Scaffolds: Plasma Immersion Ion Implantation Increases Osteoconduction.
Automated segmentation of lungs and lung tumors in mouse micro-CT scans.
Synergistic Effect of Reverse Drilling and Bone Dust on Femoral Tendon-Bone Healing After Anterior Cruciate Ligament Reconstruction in a Rabbit Model.
Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates.
Repeated Contrast-Enhanced Micro-CT Examinations Decrease Animal Welfare and Influence Tumor Physiology.
An orally administered gold nanocluster with ROS scavenging for inflammatory bowel disease treatment.
Ligand-Specific Nano-Contrast Agents Promote Enhanced Breast Cancer CT Detection at 0.5 mg Au.
LONP1 downregulation with ageing contributes to osteoarthritis via mitochondrial dysfunction.
PixelPrint: three-dimensional printing of patient-specific soft tissue and bone phantoms for CT.
Verification of multi-structure targeting in chronic microelectrode brain recordings from CT scans.
Mitigation of the turbulence within an arteriovenous fistula with a stent implantation.
In Vivo Studies of Laser-Ablated Gold Nanoparticles as Dose Enhancers for Binary Radiotherapy of Cancer.
Anesthesia with Tricaine Methanesulfonate (MS222) and Propofol and Its Use for Computed Tomography of Red Swamp Crayfish (Procambarus clarkii).
2021
Skin protective and regenerative effects of RM191A, a novel superoxide dismutase mimetic.
Dopamine D2/3 Receptor Availabilities and Evoked Dopamine Release in Striatum Differentially Predict Impulsivity and Novelty Preference in Roman High- and Low-Avoidance Rats.
Photosensitizer-based multimodal PSMA-targeting ligands for intraoperative detection of prostate cancer.
Neural crest-specific loss of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction and disordered breathing, modeling obstructive sleep apnea.
Interventional nuclear medicine: "click" chemistry as an: In vivo targeting strategy for imaging microspheres and bacteria.
Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.
Cyclodextrin-based host-guest complexes loaded with regorafenib for colorectal cancer treatment.
89 Zr‐Labeled Domain Ii‐Specific Scfv‐Fc Immunopet Probe for Imaging Epidermal Growth Factor Receptor in Vivo.
Precision Medicine in Ossiculoplasty.
Highly tumor-specific and long-acting iodine-131 microbeads for enhanced treatment of hepatocellular carcinoma with low-dose radio-chemoembolization.
Modulation of the Pharmacokinetics of a Radioligand Targeting Carbonic Anhydrase-IX with Albumin-Binding Moieties.
Site-specific dual-labeling of a vhh with a chelator and a photosensitizer for nuclear imaging and targeted photodynamic therapy of egfr-positive tumors.
Characterization of cardiovascular injury in mice following partial-heart irradiation with clinically relevant dose and fractionation.
A system-agnostic, adaptable and extensible animal support cradle system for cardio-respiratory-synchronised, and other, multi-modal imaging of small animals.
Effect of 5-HT2A receptor antagonism on levels of D2/3 receptor occupancy and adverse behavioral side-effects induced by haloperidol: a SPECT imaging study in the rat.
An anatomical thermal 3d model in preclinical research: Combining ct and thermal images.
The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type 2 immunity-independent inhibition of food intake.
Human monoclonal antibodies against Staphylococcus aureus surface.
Collagen-Induced Temporomandibular Joint Arthritis Juvenile Rat Animal Model.
A novel mouse model of radiation-induced cardiac injury reveals biological and radiological biomarkers of cardiac dysfunction with potential clinical relevance.
Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid.
Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton.
Automatic attenuation map estimation from SPECT data only for brain perfusion scans using convolutional neural networks.
An Experimental Study on [125I]I-pHLIP (Var7) for SPECT/CT Imaging of an MDA-MB-231 Triple-Negative Breast Cancer Mouse Model by Targeting the Tumor Microenvironment.
Design of PSMA ligands with modifications at the inhibitor part: an approach to reduce the salivary gland uptake of radiolabeled PSMA inhibitors?.
Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer’s disease.
Establishing a new alveolar cleft model in rats to investigate the influence of jaw reconstructions on orthodontic tooth movement.
Versatile labeling of multiple radionuclides onto a nanoscale metal-organic framework for tumor imaging and radioisotope therapy.
Real-time positron emission tomography evaluation of topotecan brain kinetics after ultrasound-mediated blood–brain barrier permeability.
Variation in cross-sectional shape and biomechanical properties of the bat humerus under Wolff's law.
Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm.
Radionuclide labeled gold nanoclusters boost effective anti-tumor immunity for augmented radio-immunotherapy of cancer.
Decorating sdabs with chelators: Effect of conjugation on biodistribution and functionality.
TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss.
Iodinated BSA Nanoparticles for Macrophage-Mediated CT Imaging and Repair of Gastritis.
BiVO4/Fe3O4@polydopamine superparticles for tumor multimodal imaging and synergistic therapy.
Impact of a CD36 inhibitor on Porphyromonas gingivalis mediated atherosclerosis.
Femoral strength and strains in sideways fall: Validation of finite element models against bilateral strain measurements.
Ginkgolide B monotherapy reverses osteoporosis by regulating oxidative stress-mediated bone homeostasis.
A simple, open and extensible gating Control unit for cardiac and respiratory synchronisation control in small animal MRI and demonstration of its robust performance in steady-state maintained CINE-MRI.
3D-printed saw guides for lower arm osteotomy, a comparison between a synthetic CT and CT-based workflow.
Novel human antibodies to insulin growth factor 2 receptor (Igf2r) for radioimmunoimaging and therapy of canine and human osteosarcoma.
BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin–YAP Signaling Axis.
Preparation of Heat-Denatured Macroaggregated Albumin for Biomedical Applications Using a Microfluidics Platform.
An Effective and Reliable Methodology for Deep Machine Learning Application in Caries Detection (Vol. , pp. 1-16) [Computer software].
Efficient Monte-Carlo based system modelling for image reconstruction in preclinical pinhole SPECT.
Topographic features of nano-pores within the osteochondral interface and their effects on transport properties –a 3D imaging and modeling study.
CPPs to the Test: Effects on Binding, Uptake and Biodistribution of a Tumor Targeting Nanobody.
Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts.
Novel treatment for glioblastoma delivered by a radiation responsive and radiopaque hydrogel.
Characterization of Intrinsically Radiolabeled Poly(lactic- co-glycolic acid) Nanoparticles for ex Vivo Autologous Cell Labeling and in Vivo Tracking.
CUB domain containing protein 1 (CDPC1) is a target for radioligand therapy in castration resistant prostate cancer.
211 At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer.
A Novel Radiotracer for Molecular Imaging and Therapy of Gastrin-Releasing Peptide Receptor Positive Prostate Cancer.
Biocompatible nanomicelles for sensitive detection and photodynamic therapy of early-stage cancer.
Advances in micro-CT imaging of small animals.
SPECT/CT imaging of inflammation and calcification in human carotid atherosclerosis to identify the plaque at risk of rupture.
Diagnostic Radionuclides Labeled on Biomimetic Nanoparticles for Enhanced Follow-Up Photothermal Therapy of Cancer.
Simultaneous SPECT imaging with 123I and 125I - a practical approach to assessing a drug and its carrier at the same time with dual imaging.
Electroacupuncture suppresses glucose metabolism and GLUT-3 expression in medial prefrontal cortical in rats with neuropathic pain.
Arteriovenous fistula-induced cardiac remodeling shows cardioprotective features in mice.
The Chromatin Regulator Ankrd11 Controls Palate and Cranial Bone Development.
Mtu1 defects are correlated with reduced osteogenic differentiation.
In vitro and in vivo evaluation of [125/123I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([125/123I]-OI5V) as a potential sigma-1 receptor ligand for SPECT.
Positron range-free and multi-isotope tomography of positron emitters.
On the ability of experimental impact measures to predict tooth injuries in an ex vivo swine model.
Heterotypic tumor models through freeform printing into photostabilized granular microgels.
A Model System to Explore the Detection Limits of Antibody-Based Immuno-SPECT Imaging of Exclusively Intranuclear Epitopes.
Augmenting a dynamic hip screw with a calcium sulfate/hydroxyapatite biomaterial.
Evaluation of different grafting materials for alveolar cleft repair in the context of orthodontic tooth movement in rats.
Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells.
The design and preclinical evaluation of a single‐label bimodal nanobody tracer for image‐guided surgery.
68Ga- and 211At-Labeled RGD Peptides for Radiotheranostics with Multiradionuclides.
Reshaping the Inflammatory Environment in Rheumatoid Arthritis Joints by Targeting Delivery of Berberine with Platelet‐Derived Extracellular Vesicles.
Concussion/Mild Traumatic Brain Injury (TBI) Induces Brain Insulin Resistance: A Positron Emission Tomography (PET) Scanning Study.
Nasal Septum Deviation as the Consequence of BMP-Controlled Changes to Cartilage Properties.
Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides.
Fluorescence-Activated Cell Sorting-Radioligand Treated Tissue (FACS-RTT) to Determine the Cellular Origin of Radioactive Signal.
Iron oxide nanoparticles augment the intercellular mitochondrial transfer–mediated therapy.
Multiscale computational modeling of cancer growth using features derived from microCT images.
Targeted design of a recombinant tracer for SPECT renal imaging.
Convolutional neural network based attenuation correction for 123I-FP-CIT SPECT with focused striatum imaging.
Intraosseous Injection of Calcium Phosphate Polymer-Induced Liquid Precursor Increases Bone Density and Improves Early Implant Osseointegration in Ovariectomized Rats.
A 2-plane micro-computed tomographic alveolar bone measurement approach in mice.
Imaging carbonic anhydrase IX as a method for monitoring hypoxia-related radioresistance in preclinical head and neck cancer models.
Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics.
Early environmental enrichment and impoverishment differentially affect addiction-related behavioral traits, cocaine-taking, and dopamine D2/3 receptor signaling in a rat model of vulnerability to drug abuse.
Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration.
Photo-Driven Delivery of 125I-Labeled Nanomicelles for Nucleus-Targeted Internal Conversion Electron-Based Cancer Therapy.
Preclinical study of 212Pb alpha-radioimmunotherapy targeting CD20 in non-Hodgkin lymphoma.
Transcranial Theranostic Ultrasound for Pre-Planning and Blood-Brain Barrier Opening: A Feasibility Study Using an Imaging Phased Array In Vitro and In Vivo.
Semiconducting polymer nano-radiopharmaceutical for combined radio-photothermal therapy of pancreatic tumor.
Engineered osteoclasts as living treatment materials for heterotopic ossification therapy.
A non-internalised CD38-binding radiolabelled single-domain antibody fragment to monitor and treat multiple myeloma.
The Role of Ligand Acid–Base Reaction in the Facile Synthesis of Alkali Metal Neodymium Penta- and Heptafluoride Nanocrystals.
Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer.
Feasibility of 125I-RGD uptake as a marker of angiogenesis after myocardial infarction.
A Hydroxypropyl Methylcellulose Film Loaded with AFCP Nanoparticles for Inhibiting Formation of Enamel White Spot Lesions.
Photodynamic Therapy Targeting Macrophages Using IRDye700DX-Liposomes Decreases Experimental Arthritis Development.
Impact of juxta-anastomotic stent implantation on the haemodynamics within a single representative patient AVF.
Rapidly liver-clearable rare-earth core-shell nanoprobe for dual-modal breast cancer imaging in the second near-infrared window.
Effect of Nanoparticle Synthetic Conditions on Ligand Coating Integrity and Subsequent Nano-Biointeractions.
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade.
In Vivo Evaluation of Gallium-68-Labeled IRDye800CW as a Necrosis Avid Contrast Agent in Solid Tumors.
Injectable and Self-Healing Hydrogels with Double-Dynamic Bond Tunable Mechanical, Gel–Sol Transition and Drug Delivery Properties for Promoting Periodontium Regeneration in Periodontitis.
Radioactive nano-oxygen generator enhance anti-tumor radio-immunotherapy by regulating tumor microenvironment and reducing proliferation.
Tissue‐Engineered Bone Functionalized with MoS 2 Nanosheets for Enhanced Repair of Critical‐Size Bone Defect in Rats.
Quantitative radionuclide imaging analysis of enhanced drug delivery induced by photoimmunotherapy.
Tooth and root size as determined from 0.25- and 0.30-mm voxel size cone-beam CT imaging when contrasted to micro-CT scans (0.06 mm): An ex vivo study.
PET Imaging Using [18F] olaparib in Mouse Models of Malignant Glioma : Considerations for Molecular Imaging and Radionuclide Therapy Targeting PARP.
Synthesis and Evaluation of Technetium-99m- labeled pH ( low ) Insertion Peptide Variant 7 for Early Diagnosis of MDA-MB-231 Triple-Negative Breast Cancer by Targeting the Tumor Microenvironment.
Superhydrophilic multifunctional nanotextured titanium dental implants: in vivo short and long-term response in a porcine model.
89Zr-labeled PSMA ligands for pharmacokinetic PET imaging and dosimetry of PSMA-617 and PSMA-I&T: a preclinical evaluation and first in man.
Biological Distribution of Orally Administered [123I]MIBG for Estimating Gastrointestinal Tract Absorption.
Radioimmunotherapy Targeting IGF2R on Canine-Patient-Derived Osteosarcoma Tumors in Mice and Radiation Dosimetry in Canine and Pediatric Models.
Nanocomposite fibrous scaffold mediated mandible reconstruction and dental rehabilitation: An experimental study in pig model.
Albumin-binding lipid-aptamer conjugates for cancer immunoimaging and immunotherapy.
Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control.
2020
Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging.
111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis.
Hybrid tracers based on cyanine backbones targeting prostate-specific membrane antigen: Tuning pharmacokinetic properties and exploring dye-protein interaction [Computer software].
Optimized sampling for high resolution multi-pinhole brain SPECT with stationary detectors.
Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems.
Early detection in a mouse model of pancreatic cancer by imaging DNA damage response signaling.
Bone-Seeking Albumin-Nanomedicine for in Vivo Imaging and Therapeutic Monitoring.
212Pb α-radioimmunotherapy targeting CD38 in multiple myeloma: A preclinical study.
Serial examination of cardiac function and perfusion in growing rats using SPECT/CT for small animals.
Radioprotective Garment-Inspired Biodegradable Polymetal Nanoparticles for Enhanced CT Contrast Production.
In vivo absolute quantification of striatal and extrastriatal D2/3 receptors with [123I]epidepride SPECT.
Radioactive labeling of milk-derived exosomes with99mTC and in vivo tracking by SPECT imaging.
Radiolabeled cCPE peptides for SPECT imaging of claudin-4 overexpression in pancreatic cancer.
Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles.
Airway remodeling in ferrets with cigarette smoke-induced COPD using μCT imaging.
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity.
Imaging of inflammatory cellular protagonists in human atherosclerosis: a dual-isotope SPECT approach.
H 2 CHX hox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [ nat/67/68 Ga]Ga 3+.
Preclinical Single Photon Emission Computed Tomography of Alpha Particle-Emitting Radium-223.
Immuno-imaging of ICAM-1 in tumours by SPECT.
Characterization of a mouse model to study the relationship between apical periodontitis and atherosclerosis.
Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation.
EXIRAD-3D: Fast automated three-dimensional autoradiography.
In Vivo Evaluation of Indium-111–Labeled 800CW as a Necrosis-Avid Contrast Agent.
Attenuated: Salmonella typhimurium-mediated tumour targeting imaging based on peptides.
Effect of peritumoral bupivacaine on primary and distal hyperalgesia in cancer-induced bone pain.
Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice.
Mesenchymal Bmp7 Controls Onset of Tooth Mineralization: A Novel Way to Regulate Molar Cusp Shape.
BiVO4@Bi2S3Heterojunction Nanorods with Enhanced Charge Separation Efficiency for Multimodal Imaging and Synergy Therapy of Tumor.
Targeting glutamine metabolism slows soft tissue sarcoma growth.
Monosized Polymeric Microspheres Designed for Passive Lung Targeting: Biodistribution and Pharmacokinetics after Intravenous Administration.
Targeted photodynamic therapy selectively kills activated fibroblasts in experimental arthritis.
Haemophilus influenzae persists in biofilm communities in a smoke-exposed ferret model of COPD.
Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency.
An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: Mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells.
Design of iodinated radioligands for SPECT imaging of central human 5-HT4R using a ligand lipophilicity efficiency approach.
Quasi-amorphous and Hierarchical Fe2O3 Supraparticles: Active T1-Weighted Magnetic Resonance Imaging in Vivo and Renal Clearance.
Radiolabeled human monoclonal antibody 067-213 has the potential for noninvasive quantification of cd73 expression.
Freeform printing of heterotypic tumor models within cell-laden microgel matrices.
Thallium-201 Imaging in Intact Olfactory Sensory Neurons with Reduced Pre-Synaptic Inhibition In Vivo.
Super Spatial Resolution (SSR) method for small animal SPECT imaging: A Monte Carlo study.
Evaluating Microelectrode Arrays in Peripheral Nerve Using Micro Computed Tomography.
Noninvasive Monitoring of Glycemia-Induced Regulation of GLP-1R Expression in Murine and Human Islets of Langerhans.
The clinical utilities of multi-pinhole single photon emission computed tomography.
Prospective comparison of PET imaging with PSMA-targeted 18F-DCFPyL versus NA18F for bone lesion detection in patients with metastatic prostate cancer.
Moment arm function dictates patella sagittal height anatomy: Rabbit epiphysiodesis model alters limb length ratios and subsequent patellofemoral anatomical development.
Bioimaging and Biodistribution of the Metal-Ion-Controlled Self-Assembly of PYY3–36 Studied by SPECT/CT.
Why the preclinical imaging field needs nuclear medicine technologists and radiographers?.
nkx3.2 mutant zebrafish accommodate jaw joint loss through a phenocopy of the head shapes of Paleozoic jawless fish.
Fabrication of multifunctional polydopamine-coated gold nanobones for PA/CT imaging and enhanced synergistic chemo-photothermal therapy.
Decreased gas-diffusion electrode porosity due to increased electrocatalyst loading leads to diffusional limitations in cathodic H2O2 electrosynthesis.
[131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma.
Improved Noninvasive In Vivo Tracking of AAV-9 Gene Therapy Using the Perchlorate-Resistant Sodium Iodide Symporter from Minke Whale.
Smooth Muscle Cell Reprogramming in Aortic Aneurysms.
Multimodal CEA-targeted image-guided colorectal cancer surgery using 111in-labeled SGM-101.
Analysis of the bone fracture targeting properties of osteotropic ligands.
Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer.
Disturbed gut microbiota and bile homeostasis in Giardia -infected mice contributes to metabolic dysregulation and growth impairment.
Capabilities of multi-pinhole SPECT with two stationary detectors for in vivo rat imaging.
Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis.
Histological and molecular characterization of the growing nasal septum in mice.
EXIRAD-HE: Multi-pinhole high-resolution ex vivo imaging of high-energy isotopes.
Extensive preclinical evaluation of lutetium-177-labeled PSMA-specific tracers for prostate cancer radionuclide therapy.
A universal dual mechanism immunotherapy for the treatment of influenza virus infections.
Ischial tuberosity: new donor site for bone grafts in animal cleft research.
Nimotuzumab site-specifically labeled with89zr and225ac using spytag/spycatcher for pet imaging and alpha particle radioimmunotherapy of epidermal growth factor receptor positive cancers.
3D optical/CT as a preclinical companion imaging platform for glioblastoma drug development.
Development of gold nanorods conjugated with radiolabeled anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibody as single-photon emission computed tomography/photoacoustic dual-imaging probes targeting HER2-positive tumors.
Proof of concept study for increasing tenascin-C-targeted drug delivery to tumors previously subjected to therapy: X-irradiation increases tumor uptake.
Microstructural volumetric analysis of the jaw following dental implantation under systemic bisphosphonate delivery: An in vivo and ex vivo rat study.
Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers.
Bone tumor–targeted delivery of theranostic 195mPt-bisphosphonate complexes promotes killing of metastatic tumor cells.
Induction assisted friction stir welding: a review.
[18F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging.
Dietary and body-mass reconstruction of the Miocene neotropical bat Notonycteris magdalenensis (Phyllostomidae) from la Venta, Colombia.
Development and feasibility of quantitative dynamic cardiac imaging for mice using μSPECT.
Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer.
Tumor microenvironment (TME)-activatable circular aptamer-PEG as an effective hierarchical-targeting molecular medicine for photodynamic therapy.
Engineering NIR-IIb fluorescence of Er-based lanthanide nanoparticles for through-skull targeted imaging and imaging-guided surgery of orthotopic glioma.
Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles.
Effect of modulating FcRn binding on direct and pretargeted tumor uptake of full-length antibodies.
Dissolution and Vertical Transport of Uranium from Stable Mineral Forms by Plants as Influenced by the Co-occurrence of Uranium with Phosphorus.
Phylogeny and foraging behaviour shape modular morphological variation in bat humeri.
Polymeric Nanoparticles with Neglectable Protein Corona.
Accelerated image reconstruction by a combined dual-matrix dual-voxel approach.
Therapeutic Efficacy of 213 Bi-labeled sdAbs in a Preclinical Model of Ovarian Cancer.
Imaging DNA damage repair in vivo after 177Lu-DOTATATE therapy.
Visualization of AMPA receptors in living human brain with positron emission tomography.
Paradoxical aortic stiffening and subsequent cardiac dysfunction in Hutchinson–Gilford progeria syndrome.
2019
Imaging of atherosclerosis, targeting LFA-1 on inflammatory cells with 111In-DANBIRT.
TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer's disease.
Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy.
111 In-Labeled Glycoprotein Nonmetastatic b (GPNMB) Targeted Gemini Surfactant-Based Nanoparticles against Melanoma: In Vitro Characterization and in Vivo Evaluation in Melanoma Mouse Xenograft Model.
In Vivo Photoacoustic/Single-Photon Emission Computed Tomography Imaging for Dynamic Monitoring of Aggregation-Enhanced Photothermal Nanoagents.
Preclinical evaluation of 111In-labeled peGylated maytansine nimotuzumab drug conjugates in EGFR-positive cancer models.
Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages.
Boosting the Radiosensitizing and Photothermal Performance of Cu2-xSe Nanocrystals for Synergetic Radiophotothermal Therapy of Orthotopic Breast Cancer.
Quantification of myocardial uptake rate constants in dynamic small-animal SPECT using a cardiac phantom.
Radioembolization of hepatocellular carcinoma with built-in dosimetry: First in vivo results with uniformly-sized, biodegradable microspheres labeled with 188Re.
PD-L1 microSPECT/CT imaging for longitudinal monitoring of PD-L1 expression in syngeneic and humanized mouse models for cancer.
Data Curation for Preclinical and Clinical Multimodal Imaging Studies.
cRGD-decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo.
Tumor imaging using radiolabeled matrix metalloproteinase-activated anthrax proteins.
Iodine-Rich Polymersomes Enable Versatile SPECT/CT Imaging and Potent Radioisotope Therapy for Tumor in Vivo.
Characterization of BAT activity in rats using invasive and non-invasive techniques.
Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease.
Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy.
A pretargeted multimodal approach for image-guided resection in a xenograft model of colorectal cancer.
Restoration of brain circulation and cellular functions hours post-mortem.
Nanoagents Based on Poly(ethylene glycol)-b-Poly(l-thyroxine) Block Copolypeptide for Enhanced Dual-Modality Imaging and Targeted Tumor Radiotherapy.
Daratumumab-225Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors.
Comparative radioimmunotherapy of experimental melanoma with novel humanized antibody to melanin labeled with 213bismuth and 177lutetium.
Click Chemistry in the Design and Production of Hybrid Tracers.
Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.
Noninvasive in vivo quantification of adeno-associated virus serotype 9–mediated expression of the sodium/iodide symporter under hindlimb ischemia and neuraminidase desialylation in skeletal muscle using single-photon emission computed tomography/computed.
A carbon-fiber sheet resistor for mr-, ct-, spect-, and pet-compatible temperature maintenance in small animals.
Evaluating a single domain antibody targeting human PD-L1 as a nuclear imaging and therapeutic agent.
Fluorescence-activated cell sorting to reveal the cell origin of radioligand binding.
Chlorambucil targets BRCA 1/2‐deficient tumours and counteracts PARP inhibitor resistance.
Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice.
Angiotensin Receptor Neprilysin Inhibitor Attenuates Myocardial Remodeling and Improves Infarct Perfusion in Experimental Heart Failure.
Rational Design and Synthesis of a Metalloproteinase-Activatable Probe for Dual-Modality Imaging of Metastatic Lymph Nodes in Vivo.
Evaluation of pinhole collimator materials for micron-resolution ex vivo SPECT.
Dual-isotope imaging allows in vivo immunohistochemistry using radiolabelled antibodies in tumours.
Imaging of translocator protein upregulation is selective for pro-inflammatory polarized astrocytes and microglia.
Plant-derived chlorophyll derivative loaded liposomes for tri-model imaging guided photodynamic therapy.
Development and characterization of a theranostic multimodal anti-PSMA targeting agent for imaging, surgical guidance, and targeted photodynamic therapy of PSMA-expressing tumors.
111In- And 225Ac-Labeled Cixutumumab for Imaging and α-Particle Radiotherapy of IGF-1R Positive Triple-Negative Breast Cancer [Computer software].
Measuring the Pancreatic ß Cell Mass in Vivo with Exendin SPECT during Hyperglycemia and Severe Insulitis.
Quantitatively Visualizing Tumor-Related Protease Activity in Vivo Using a Ratiometric Photoacoustic Probe.
T1/T2-weighted magnetic resonance imaging and SPECT imaging guided combined radioisotope therapy and chemotherapy using functionalized reduced graphene oxide-manganese ferrite nanocomposites.
Two-dimensional metal-organic-framework as a unique theranostic nano-platform for nuclear imaging and chemo-photodynamic cancer therapy.
Epilepsy-related and other causes of mortality in people with epilepsy: A systematic review of systematic reviews.
Activatable Hybrid Polyphosphazene-AuNP Nanoprobe for ROS Detection by Bimodal PA/CT Imaging.
Effect of Gold Nanoparticle Size on Their Properties as Contrast Agents for Computed Tomography.
Multimodal image-guided surgery of HER2-positive breast cancer using [111In]In-DTPA-trastuzumab-IRDye800CW in an orthotopic breast tumor model.
A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice.
CAIX-targeting radiotracers for hypoxia imaging in head and neck cancer models.
Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors.
Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A.
A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice.
Lymphodepletion with CD45 Radioimmunotherapy as a Targeted Conditioning Regimen Prior to Adoptive Cell Therapy or CAR-T.
Reconstructing granular particles from X-ray computed tomography using the TWS machine learning tool and the level set method.
Monitoring 111In-labelled polyisocyanopeptide (PIC) hydrogel wound dressings in full-thickness wounds.
Detection and targeting insulin growth factor receptor type 2 (IGF2R) in osteosarcoma PDX in mouse models and in canine osteosarcoma tumors.
Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection.
2018
Imaging of Folate Receptor Expressing Macrophages in the Rat Groove Model of Osteoarthritis: Using a New DOTA-Folate Conjugate.
Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles, and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics.
Enhanced Specific Activity by Multichelation of Exendin-3 Leads to Improved Image Quality and in Vivo Beta Cell Imaging.
Characterization of site-specifically conjugated monomethyl auristatin E-and duocarmycin-based anti-PSMA antibody-drug conjugates for treatment of PSMA-expressing tumors.
18F-Trifluoromethylation of Unmodified Peptides with 5-18F-(Trifluoromethyl)dibenzothiophenium Trifluoromethanesulfonate.
Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using 99m Tc-duramycin during TNF-induced SIRS.
Characterization of 111In-labeled Glucose-Dependent Insulinotropic Polypeptide as a Radiotracer for Neuroendocrine Tumors.
89Zr-nimotuzumab for immunoPET imaging of epidermal growth factor receptor I.
In vivo Biodistribution of Radiolabeled Acoustic Protein Nanostructures.
Novel light-guide-PMT geometries to reduce dead edges of a scintillation camera.
Imaging fibroblast activation protein to monitor therapeutic effects of neutralizing interleukin-22 in collagen-induced arthritis.
Investigation of Newly Prepared Biodegradable 32 P-chromic Phosphate-polylactide-co-glycolide Seeds and Their Therapeutic Response Evaluation for Glioma Brachytherapy.
Tracers for fluorescence-guided surgery: How elongation of the polymethine chain in cyanine dyes alters the pharmacokinetics of a dual-modality c[RGDyK] tracer.
Validation of 111 In-exendin SPECT for the determination of the B-cell mass in biobreeding diabetes-prone rats.
Quantification of Myocardial Perfusion Defect Size in Rats: Comparison between Quantitative Perfusion SPECT and Autoradiography.
In vivo estimation of oncolytic virus populations within tumors.
Effects of adding an albumin binder chain on [177Lu]Lu-DOTATATE.
Ultrasmall Hyperbranched Semiconducting Polymer Nanoparticles with Different Radioisotopes Labeling for Cancer Theranostics.
New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging.
Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies.
Enhancing Treatment Efficacy of 177Lu-PSMA-617 with the Conjugation of an Albumin-Binding Motif: Preclinical Dosimetry and Endoradiotherapy Studies.
Calcium Bisphosphonate Nanoparticles with Chelator-Free Radiolabeling to Deplete Tumor-Associated Macrophages for Enhanced Cancer Radioisotope Therapy.
PET imaging of PARP expression using 18F-olaparib.
Optimized image acquisition for dopamine transporter imaging with ultra-high resolution clinical pinhole SPECT.
Whole-body imaging of cell death provides a systemic, minimally invasive, dynamic, and near-real time indicator for chemotherapeutic drug toxicity.
Cu-Fe-Se Ternary Nanosheet-Based Drug Delivery Carrier for Multimodal Imaging and Combined Chemo/Photothermal Therapy of Cancer.
Monitoring the Opening and Recovery of the Blood-Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultrasmall Cu2- xSe Nanoparticles.
Blood circulation, biodistribution, and pharmacokinetics of dextran-modified black phosphorus nanoparticles.
Antitumor activity of auger electron emitter 111In delivered by modular nanotransporter for treatment of bladder cancer with EGFR overexpression.
Dual-isotope SPECT/CT imaging of the tuberculosis subunit vaccine H56/CAF01: Induction of strong systemic and mucosal IgA and T-cell responses in mice upon subcutaneous prime and intrapulmonary boost immunization.
A 89 Zr-labeled lipoplex nanosystem for image-guided gene delivery: Design, evaluation of stability and in vivo behavior.
Quantitative Imaging of the Hypoxia-Related Marker CAIX in Head and Neck Squamous Cell Carcinoma Xenograft Models.
Sulfonyl-Containing Boronate Caps for Optimization of Biological Properties of 99m Tc(III) Radiotracers [ 99m TcCl(CDO)(CDOH) 2 B-R] (CDOH 2 = Cyclohexanedione Dioxime).
Prognostic Value of Early Evaluation of Left Ventricular Dyssynchrony After Myocardial Infarction.
Dual SPECT imaging of 111In and 67Ga to simultaneously determine in vivo the pharmacokinetics of different radiopharmaceuticals: A quantitative tool in pre-clinical research.
Dual-radiotracer translational SPECT neuroimaging. Comparison of three methods for the simultaneous brain imaging of D2/3 and 5-HT2A receptors.
Biodegradable Nanoagents with Short Biological Half-Life for SPECT/PAI/MRI Multimodality Imaging and PTT Therapy of Tumors.
Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles - A potential theranostic agent for pulmonary metastatic disease.
Highly effective radioisotope cancer therapy with a non-therapeutic isotope delivered and sensitized by nanoscale coordination polymers.
Detection of lymph node metastasis with near-infrared upconversion luminescent nanoprobes.
Ultra-small nanocluster mediated synthesis of Nd3+-doped core-shell nanocrystals with emission in the second near-infrared window for multimodal imaging of tumor vasculature.
An acidic pH/reduction dual-stimuli responsive nanoprobe for enhanced CT imaging of tumours: In vivo.
Noninvasive Multimodal Imaging of Osteosarcoma and Lymph Nodes Using a 99mTc-Labeled Biomineralization Nanoprobe.
Photosensitizer-crosslinked in-situ polymerization on catalase for tumor hypoxia modulation & enhanced photodynamic therapy.
Oral administration of highly bright Cr3+ doped ZnGa2O4 nanocrystals for in vivo targeted imaging of orthotopic breast cancer.
Injectable tissue integrating networks from recombinant polypeptides with tunable order.
Comparison of the accuracy of FMT/CT and PET/MRI for the assessment of antibody biodistribution in squamous cell carcinoma xenografts.
[99mTc]duramycin for cell death imaging: Impact of kit formulation, purification and species difference.
System geometry optimization for molecular breast tomosynthesis with focusing multi-pinhole collimators.
Quantitative SPECT imaging and biodistribution point to molecular weight independent tumor uptake for some long-circulating polymer nanocarriers.
In vivo stability of supramolecular host–guest complexes monitored by dual-isotope multiplexing in a pre-targeting model of experimental liver radioembolization.
First Whole-Body Three-Dimensional Tomographic Imaging of Alpha Particle Emitting Radium-223.
Cancer radiotheranostics targeting carbonic anhydrase-IX with 111 In- and 90 Y-labeled ureidosulfonamide scaffold for SPECT imaging and radionuclide-based therapy.
Evaluation of 209At as a theranostic isotope for 209At-radiopharmaceutical development using high-energy SPECT.
H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry.
99mTc(CO)3+ labeled domain I/II-specific anti-EGFR (scFv)2 antibody fragment for imaging EGFR expression.
2017
Liposomal treatment of experimental arthritis can be monitored noninvasively with a radiolabeled anti-fibroblast activation protein antibody.
In vivo imaging of antileukemic drug asparaginase reveals a rapid macrophage-mediated clearance from the bone marrow.
68Ga/177Lu-NeoBOMB1, a novel radiolabeled GRPR antagonist for theranostic use in oncology.
99mTc-duramycin SPECT imaging of early tumor response to targeted therapy: A comparison with 18F-FDG PET.
Quantitative and longitudinal imaging of intramuscular transplanted islets of Langerhans with SPECT using [123I]IBZM.
A single-scan protocol for absolute D2/3 receptor quantification with [123I]IBZM SPECT.
188Re image performance assessment using small animal multi-pinhole SPECT/PET/CT system.
Preparation, cytotoxicity, and in vivo antitumor efficacy of 111in-labeled modular nanotransporters.
Iminodiacetic acid as bifunctional linker for dimerization of cyclic RGD peptides.
Hybrid imaging labels: Providing the link between mass spectrometry-based molecular pathology and theranostics.
Preclinical imaging characteristics and quantification of Platinum-195m SPECT.
Multi-isotope SPECT imaging of the 225Ac decay chain: Feasibility studies.
18F-FDG as an inflammation biomarker for imaging dengue virus infection and treatment response.
Development and evaluation of a new modular nanotransporter for drug delivery into nuclei of pathological cells expressing folate receptors.
Preclinical evaluation of PAC1 targeting with radiolabeled Maxadilan.
Radioiodination of BODIPY and its application to a nuclear and optical dual functional labeling agent for proteins and peptides.
Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging.
Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma.
P-NO2-Bn-H4neunpa and H4neunpa-Trastuzumab: Bifunctional Chelator for Radiometalpharmaceuticals and 111In Immuno-Single Photon Emission Computed Tomography Imaging.
99mTc-3Cboroxime: A novel 99mTc(III) complex [99mTcCl(CDO)(CDOH)2B-3C] (CDOH2 = cyclohexanedione dioxime; 3C-B(OH)2 = 3-(carbamoylphenyl)boronic acid) with high heart uptake and long myocardial retention.
Radiolabelled polymeric IgA: From biodistribution to a new molecular imaging tool in colorectal cancer lung metastases.
Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction.
64Cu-ATSM internal radiotherapy to treat tumors with bevacizumab-induced vascular decrease and hypoxia in human colon carcinoma xenografts.
Evaluation of 99mTc-3PRGD2 integrin receptor imaging in hepatocellular carcinoma tumour-bearing mice: comparison with 18F-FDG metabolic imaging.
Use of cyclic backbone NGR-based SPECT to increase efficacy of postmyocardial infarction angiogenesis imaging.
Tumor Microenvironment-Triggered Aggregation of Antiphagocytosis 99mTc-Labeled Fe3O4 Nanoprobes for Enhanced Tumor Imaging In Vivo.
Monodisperse Dual Plasmonic Au@Cu2-xE (E= S, Se) Core@Shell Supraparticles: Aqueous Fabrication, Multimodal Imaging, and Tumor Therapy at in Vivo Level.
Ultrasmall Magnetic CuFeSe2 Ternary Nanocrystals for Multimodal Imaging Guided Photothermal Therapy of Cancer.
Activation of brain glucose metabolism ameliorating cognitive impairment in APP/PS1 transgenic mice by electroacupuncture.
Detection of micrometastases using SPECT/fluorescence dual-modality imaging in a CEA-expressing tumor model.
High-Resolution 4D Preclinical Single-Photon Emission Computed Tomography/X-ray Computed Tomography Imaging of Technetium Transport within a Heterogeneous Porous Media.
Non-diverging analytical expression for the sensitivity of converging SPECT collimators.
2016
SPECT vs. PET monitoring of bone defect healing and biomaterial performance in vivo.
5-HT2A receptor SPECT imaging with [123I]R91150 under P-gp inhibition with tariquidar: More is better?.
Monitoring therapy response of experimental arthritis with radiolabeled tracers targeting fibroblasts, macrophages, or integrin αvβ3.
Utilizing high-energy γ-photons for high-resolution 213Bi SPECT in mice.
Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia.
Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging.
SPECT/CT Imaging of Pluronic Nanocarriers with Varying Poly(ethylene oxide) Block Length and Aggregation State.
Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography.
SPECT-OPT multimodal imaging enables accurate evaluation of radiotracers for β-cell mass assessments.
Optimizing modelling in iterative image reconstruction for preclinical pinhole PET.
Towards personalized treatment of prostate cancer: PSMA I&T, a promising prostate-specific membrane antigen-targeted theranostic agent.
High-resolution clustered pinhole 131Iodine SPECT imaging in mice.
In vivo biodistribution of stable spherical and filamentous micelles probed by high-sensitivity SPECT.
Comparison of LDPI to SPECT perfusion imaging using 99mTc-sestamibi and 99mTc-pyrophosphate in a murine ischemic hind limb model of neovascularization.
Pre-clinical Evaluation of a Cyanine-Based SPECT Probe for Multimodal Tumor Necrosis Imaging.
Preclinical evaluation of [111In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity.
Ambient Aqueous Synthesis of Ultrasmall PEGylated Cu 2− x Se Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer.
Rhenium-188 Labeled Tungsten Disulfide Nanoflakes for Self-Sensitized, Near-Infrared Enhanced Radioisotope Therapy.
Ultrasmall Biocompatible WO 3− x Nanodots for Multi-Modality Imaging and Combined Therapy of Cancers.
Novel 99mTc(III) Complexes [99mTcCl(CDO)(CDOH)2B-R] (CDOH2 = Cyclohexanedione Dioxime) Useful as Radiotracers for Heart Imaging.
Radiolabeled cyclic RGD peptides as radiotracers for tumor imaging.
Ultrasmall Biocompatible Bi2Se3 Nanodots for Multimodal Imaging-Guided Synergistic Radiophotothermal Therapy against Cancer.
SPECT of Transplanted Islets of Langerhans by Dopamine 2 Receptor Targeting in a Rat Model.
Similarity-regulation of OS-EM for accelerated SPECT reconstruction.
Imaging, biodistribution, and dosimetry of radionuclide-labeled PD-L1 antibody in an immunocompetent mouse model of breast cancer.
Linksventrikuläre funktionsmessungen in einem myokardinfarkt-tiermodell: Vergleich zwischen 3D-echokardiographie und EKG-getriggerte SPECT.
Tailoring Fluorescent Dyes to Optimize a Hybrid RGD-Tracer.
Early prediction of tumor response to treatment: Preclinical validation of 99mTc-Duramycin.
Synthesis, in vitro and in vivo small-animal SPECT evaluation of novel technetium labeled bile acid analogues to study (altered) hepatic transporter function.
Comparison of biological properties of 99mTc-labeled cyclic RGD Peptide trimer and dimer useful as SPECT radiotracers for tumor imaging.
Radionuclide imaging of liposomal drug delivery.
Novel 99mTc(III)-azide complexes [99mTc(N3)(CDO)(CDOH)2B-R] (CDOH2 = cyclohexanedione dioxime) as potential radiotracers for heart imaging.
Improved Quantification of the Beta Cell Mass after Pancreas Visualization with 99mTc-demobesin-4 and Beta Cell Imaging with 111In-exendin-3 in Rodents.
Noninvasive imaging of islet transplants with 111In-Exendin-3 SPECT/CT.
Molecular breast tomosynthesis with scanning focus multi-pinhole cameras.
2015
Noninvasive 3-dimensional imaging of liver regeneration in a mouse model of hereditary tyrosinemia type 1 using the sodium iodide symporter gene.
Impact of boronate capping groups on biological characteristics of novel 99mTc(III) complexes [99mTcCl(CDO)(CDOH)2B-R] (CDOH2 = cyclohexanedione dioxime).
Ultra-high-sensitivity submillimeter mouse SPECT.
Radionuclide and Fluorescence Imaging of Clear Cell Renal Cell Carcinoma Using Dual Labeled Anti-Carbonic Anhydrase IX Antibody G250.
Evaluation of a nonpeptidic ligand for imaging of cholecystokinin 2 receptor-expressing cancers.
99mTc Radiolabeling and Biological Evaluation of Nanoparticles Functionalized with a Versatile Coating Ligand.
Design of a serotonin 4 receptor radiotracer with decreased lipophilicity for single photon emission computed tomography.
SPECT imaging of glioma with radioiodinated CLINDE: Evidence from a mouse GL26 glioma model.
Development of a Hybrid Tracer for SPECT and Optical Imaging of Bacterial Infections.
Molecular imaging of angiogenesis after myocardial infarction by 111In-DTPA-cNGR and 99mTc-sestamibi dual-isotope myocardial SPECT.
Immuno-PET and immuno-SPECT of rheumatoid arthritis with radiolabeled anti-fibroblast activation protein antibody correlates with severity of arthritis.
Performance characteristics of a novel clustered multi-pinhole technology for simultaneous high-resolution SPECT/PET.
Characterization of [99mTc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis.
uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery.
Noninvasive imaging of tumor PD-L1 expression using radiolabeled Anti-PD-L1 antibodies.
111In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages.
Oncolytic measles virus as a novel therapy for malignant peripheral nerve sheath tumors.
Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging.
Radioiodinated peptidic imaging probes for in vivo detection of membrane type-1 matrix metalloproteinase in cancers.
Graft revascularization is essential for non-invasive monitoring of transplanted islets with radiolabeled exendin.
In vivo quantification of 5-HT2A brain receptors in Mdr1a KO rats with 123I-R91150 single-photon emission computed tomography.
Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.
Polydopamine as a Biocompatible Multifunctional Nanocarrier for Combined Radioisotope Therapy and Chemotherapy of Cancer.
In Vivo Simultaneous Imaging of Vascular Pool and Hypoxia with a HT-29 Tumor Model: the Application of Dual-Isotope SPECT/PET/CT.
Biodistribution of Fracture-Targeted GSK3β Inhibitor-Loaded Micelles for Improved Fracture Healing.
G-SPECT-I: a full ring high sensitivity and ultra-fast clinical molecular imaging system with < 3mm resolution.
Central delivery of iodine-125-labeled cetuximab, etanercept and anakinra after perispinal injection in rats: Possible implications for treating Alzheimer's disease.
Comparison of three remote radiolabelling methods for long-circulating liposomes.
Drug composition matters: The influence of carrier concentration on the radiochemical purity, hydroxyapatite affinity and in-vivo bone accumulation of the therapeutic radiopharmaceutical 188Rhenium-HEDP.
111In-Cetuximab-F(ab′)2 SPECT and 18F-FDG PET for prediction and response monitoring of combined-modality treatment of human head and neck carcinomas in a mouse model.
2014
Comparison of 4D-MicroSPECT and MicroCT for murine cardiac function.
Anatomical and functional imaging of myocardial infarction in mice using micro-CT and eXIA 160 contrast agent.
Three-dimensional histologic validation of high-resolution spect of antibody distributions within xenografts.
Combination of single-photon emission computed tomography and magnetic resonance imaging to track 111in-oxine-labeled human mesenchymal stem cells in neuroblastoma-bearing mice.
Small-animal single-photon emission computed tomographic imaging of the brain serotoninergic systems in wild-type and Mdr1a knockout rats.
In vivo and in vitro evidence that 99mTc-HYNIC-interleukin-2 is able to detect T lymphocytes in vulnerable atherosclerotic plaques of the carotid artery.
Bench to bedside development of GMP grade Rhenium-188-HEDP, a radiopharmaceutical for targeted treatment of painful bone metastases.
Dynamics of IGF-1R expression during endocrine breast cancer treatment.
Quarter-millimeter-resolution molecular mouse imaging with U-SPECT⁺.
Folate receptor-β imaging using 99mTc-folate to explore distribution of polarized macrophage populations in human atherosclerotic plaque.
OAT3-mediated extrusion of the 99mTc-ECD metabolite in the mouse brain.
Assessing cardiac injury in mice with dual energy-MicroCT, 4D-MicroCT, and MicroSPECT imaging after partial heart irradiation.
Oncolytic vaccinia virotherapy for endometrial cancer.
Dual-modality image-guided surgery of prostate cancer with a radiolabeled fluorescent anti-PSMA monoclonal antibody.
Pretargeted dual-modality immuno-spect and near-infrared fluorescence imaging for image-guided surgery of prostate cancer.
Optimizing lutetium 177-anti-carbonic anhydrase ix radioimmunotherapy in an intraperitoneal clear cell renal cell carcinoma xenograft model.
SPECT- and fluorescence image-guided surgery using a dual-labeled carcinoembryonic antigen-targeting antibody.
Can 111In-RGD2 monitor response to therapy in head and neck tumor xenografts?.
Imaging integrin αvβ3 on blood vessels with 111In-RGD2 in head and neck tumor xenografts.
Early response monitoring with 18F-FDG PET and cetuximab-F(ab′)2-SPECT after radiotherapy of human head and neck squamous cell carcinomas in a mouse model.
Performance assessment of a preclinical PET scanner with pinhole collimation by comparison to a coincidence-based small-animal PET scanner.
Influence of respiratory gating, image filtering, and animal positioning on high-resolution electrocardiography-gated murine cardiac single-photon emission computed tomography.
Impact of Multiple Negative Charges on Blood Clearance and Biodistribution Characteristics of 99mTc-Labeled Dimeric Cyclic RGD Peptides.
Development of kit formulations for 99mTcN-MPO: A cationic radiotracer for myocardial perfusion imaging.
The role of Preclinical SPECT in oncological and neurological research in combination with either CT or MRI.
Micro-CT of rodents: State-of-the-art and future perspectives.
Cetuximab reduces the accumulation of radiolabeled bevacizumab in cancer xenografts without decreasing VEGF expression.
High-resolution Medium-sized Animal Multi-pinhole SPECT with Stationary Detectors.
2013
Evaluation of a technetium-99m labeled bombesin homodimer for GRPR imaging in prostate cancer.
Intratumoral Administration of Holmium-166 Acetylacetonate Microspheres: Antitumor Efficacy and Feasibility of Multimodality Imaging in Renal Cancer.
Natural Killer Cells Generated from Cord Blood Hematopoietic Progenitor Cells Efficiently Target Bone Marrow-Residing Human Leukemia Cells in NOD/SCID/IL2Rgnull Mice.
Performance evaluation of small-animal multipinhole μsPECT scanners for mouse imaging.
111In-cetuximab-F(ab')2 SPECT imaging for quantification of accessible epidermal growth factor receptors (EGFR) in HNSCC xenografts.
Microdistribution of MC1R-targeted polyplexes in murine melanoma tumor tissue.
The strength of small: Improved targeting of Insulin-like Growth Factor-1 Receptor (IGF-1R) with F(ab′)2-R1507 fragments in Ewing sarcomas.
VECTor: A preclinical imaging system for simultaneous submillimeter SPECT and PET.
Bevacizumab reduces tumor targeting of antiepidermal growth factor and anti-insulin-like growth factor 1 receptor antibodies.
99mTc-Galacto-RGD2: A novel 99mTc-labeled cyclic RGD peptide dimer useful for tumor imaging.
Monitoring tumor response to linifanib therapy with SPECT/CT using the integrin αvβ3-Targeted Radiotracer 99mTc-3P- RGD2.
Miniaturized antibodies for imaging membrane type-1 matrix metalloproteinase in cancers.
Measles Virus entry through the signaling lymphocyte activation molecule governs efficacy of mantle cell lymphoma radiovirotherapy.
In vivo visualization and quantification of (disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc- mebrofenin in mice.
Development and characterization of [123I]iodotiagabine for in-vivo GABA-transporter imaging.
Monitoring glioma growth and tumor necrosis with the U-SPECT-II/CT scanner by targeting integrin αvβ3.
Use of folate-conjugated imaging agents to target alternatively activated macrophages in a murine model of asthma.
Oral contrast enhances the resolution of in-life NIS reporter gene imaging.
Fast count-regulated osem reconstruction with adaptive resolution recovery.
Imaging of epidermal growth factor receptor expression in head and neck cancer with SPECT/CT and 111In-labeled cetuximab-F(ab′) 2.
Effects of attenuation map accuracy on attenuation-corrected micro-SPECT images.
Quantifying the effect of repetitive transcranial magnetic stimulation in the rat brain by μsPECT CBF scans.
High Resolution microSPECT imaging of Bi-213.
Optimizing image reconstruction for simultaneous sub-mm clustered pinhole PET-SPECT.
Integration of small animal SPECT and PET with other imaging modalities.
Whole-body sub-half-minute 4D pharmacokinetic SPECT in mice [Computer software].
2012
Murine cardiac images obtained with focusing pinhole SPECT are barely influenced by extra-cardiac activity.
Varenicline increases in vivo striatal dopamine D2/3 receptor binding: An ultra-high-resolution pinhole [123I]IBZM SPECT study in rats.
Imaging of human epidermal growth factor receptor type 2 expression with 18F-labeled affibody molecule Z HER2:2395 in a mouse model for ovarian cancer.
Optimization of IGF-1R SPECT/CT imaging using 111in-labeled F(ab)2 and Fab fragments of the monoclonal antibody R1507.
In vitro and in vivo characterization of three 68ga-and 111in-labeled peptides for cholecystokinin receptor imaging.
Radiolabeled gelatin type B analogues can be used for non-invasive visualisation and quantification of protein coatings on 3D porous implants.
Radiolabelled peptides for oncological diagnosis.
Quantitative immuno-SPECT monitoring of pretargeted radioimmunotherapy with a bispecific antibody in an intraperitoneal nude mouse model of human colon cancer.
Fast spiral SPECT with stationary γ-cameras and focusing pinholes.
A folate receptor-α-specific ligand that targets cancer tissue and not sites of inflammation.
Single-photon emission computed tomographic imaging of the early time course of therapy-induced cell death using technetium 99m tricarbonyl his-annexin A5 in a colorectal cancer xenograft model.
Differential loading methods for BMP-2 within injectable calcium phosphate cement.
Monitoring Breast Tumor Lung Metastasis by U-SPECT-II/CT with an Integrin α vβ 3-Targeted Radiotracer 99mtc-3P-RGD 2.
Sub-millimeter I-131 SPECT with clustered pinholes.
2011
99mtechnetium-HYNIC(tricine/TPPTS)-Aca-bombesin(7-14) as a targeted imaging agent with microSPECT in a PC-3 prostate cancer xenograft model.
Targeted multi-pinhole SPECT.
Predicting IGF-1R therapy response in bone sarcomas: Immuno-SPECT imaging with radiolabeled R1507.
Using the NEMA NU 4 PET image quality phantom in multipinhole small-animal SPECT.
Radiolabeled cetuximab: Dose optimization for epidermal growth factor receptor imaging in a head-and-neck squamous cell carcinoma model.
Molecular SPECT Imaging: An Overview.
Imaging of prostate cancer with immuno-PET and immuno-SPECT using a radiolabeled anti-EGP-1 monoclonal antibody.
99mTc-(CO)3 His-annexin A5 micro-SPECT demonstrates increased cell death by irinotecan during the vascular normalization window caused by bevacizumab.
Image quality phantom and parameters for high spatial resolution small-animal SPECT.
Quantitative multi-pinhole small-animal SPECT: Uniform versus non-uniform Chang attenuation correction.
Review and current status of SPECT scatter correction.
The effects of object activity distribution on multiplexing multi-pinhole SPECT.
An efficient simulator for pinhole imaging of PET isotopes.
Fundamental limits of spatial resolution in PET.
2010
Pixel-based subsets for rapid multi-pinhole SPECT reconstruction.
Small-animal SPECT and SPECT/CT: Application in cardiovascular research.
High-resolution tomography of positron emitters with clustered pinhole SPECT.
ImmunoSPECT and immunoPET of IGF-1R expression with the radiolabeled antibody R1507 in a triple-negative breast cancer model.
Accurate coregistration between ultra-high-resolution micro-SPECT and circular cone-beam micro-CT scanners.
Measurement of porto-systemic shunting inmice by novel three-dimensionalmicro-single photon emission computed tomography imaging enabling longitudinal follow-up.
In vitro and in vivo evaluation of [99mTc]-labeled tricarbonyl His-annexin A5 as an imaging agent for the detection of phosphatidylserine-expressing cells.
Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer.
Evaluation of the radiation dose in micro-CT with optimization of the scan protocol.
Absolute quantitative total-body small-animal SPECT with focusing pinholes.
Hippocampal deep brain stimulation induces decreased rCBF in the hippocampal formation of the rat.
In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter.
Model-based measurements of the diameter of the internal carotid artery in CT angiography images.
2009
3-D rat brain phantom for high-resolution molecular imaging.
Effect of cyclosporin A administration on the biodistribution and multipinhole μsPECT imaging of [123I]R91150 in rodent brain.
Theoretical analysis of full-ring multi-pinhole brain SPECT.
U-SPECT-II: An ultra-high-resolution device for molecular small-animal imaging.
Ultra-high Resolution Imaging of PET tracers with clustered pinholes.
Quantification of the multiplexing effects in multi-pinhole small animal SPECT: A simulation study.
Effect of oblique X-ray incidence in flat-panel computed tomography of the breast.
2008
System calibration and statistical image reconstruction for ultra-high resolution stationary pinhole SPECT.
Respiratory-gated CT as a tool for the simulation of breathing artifacts in PET and PET/CT.
2007
Multi-modality imaging on track.
The pinhole: Gateway to ultra-high-resolution three-dimensional radionuclide imaging.
Movies of dopamine transporter occupancy with ultra-high resolution focusing pinhole SPECT.
Optimizing multi-pinhole SPECT geometries using an analytical model.
Submillimeter total-body murine imaging with U-SPECT-I.
Analysis of streak artefacts on CT images using statistics of extremes.
Theoretical and Experimental Evaluation of Spatial Resolution in a Variable Resolution X-Ray Computed Tomography Scanner (Vol. , Issue December, pp. 1-206).
2005
U-SPECT-I: A novel system for submillimeter-resolution tomography with radiolabeled molecules in mice.