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Selected journal papers

Exciting applications of MILabs imaging equipment

2021

Impact of juxta-anastomotic stent implantation on the haemodynamics within a single representative patient AVF. S. Gunasekera, O. Ng, S. Thomas, R. Varcoe, C. de Silva, T. Barber, December 2021, International Journal of Heat and Fluid Flow, DOI Link
Feasibility of 125I-RGD uptake as a marker of angiogenesis after myocardial infarction. T. Yamase, J. Taki, H. Wakabayashi, A. Inaki, T. Hiromasa, H. Mori, N. Akatani, K. Ogawa, K. Shiba, S. Kinuya, November 2021, Annals of Nuclear Medicine, PubMed Link, DOI Link
Engineering Novel CD19/CD22 Dual-Target CAR-T Cells for Improved Anti-Tumor Activity. W. Zeng, Q. Zhang, Y. Zhu, R. Ou, L. Peng, B. Wang, H. Shen, Z. Liu, L. Lu, P. Zhang, S. Liu, November 2021, Cancer Investigation, PubMed Link, DOI Link
Rapidly liver-clearable rare-earth core-shell nanoprobe for dual-modal breast cancer imaging in the second near-infrared window. Z. Wei, G. Duan, B. Huang, S. Qiu, D. Zhou, J. Zeng, J. Cui, C. Hu, X. Wang, L. Wen, M. Gao, November 2021, Journal of Nanobiotechnology, PubMed Link, DOI Link
Photodynamic Therapy Targeting Macrophages Using IRDye700DX-Liposomes Decreases Experimental Arthritis Development. D. Dorst, M. Boss, M. Rijpkema, B. Walgreen, M. Helsen, D. Bos, L. van Bloois, G. Storm, M. Brom, P. Laverman, P. van der Kraan, M. Buitinga, M. Koenders, M. Gotthardt, November 2021, Pharmaceutics, PubMed Link, DOI Link
Engineered osteoclasts as living treatment materials for heterotopic ossification therapy. W. Jin, X. Lin, H. Pan, C. Zhao, P. Qiu, R. Zhao, Z. Hu, Y. Zhou, H. Wu, X. Chen, H. Ouyang, Z. Xie, R. Tang, November 2021, Nature Communications, PubMed Link, DOI Link
A non-internalised CD38-binding radiolabelled single-domain antibody fragment to monitor and treat multiple myeloma. E. Duray, M. Lejeune, F. Baron, Y. Beguin, N. Devoogdt, A. Krasniqi, Y. Lauwers, Y. Zhao, M. D’Huyvetter, M. Dumoulin, J. Caers, November 2021, Journal of Hematology & Oncology, PubMed Link, DOI Link
Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer. Q. Lecocq, P. Debie, J. Puttemans, R. Awad, L. De Beck, T. Ertveldt, Y. De Vlaeminck, C. Goyvaerts, G. Raes, M. Keyaerts, K. Breckpot, N. Devoogdt, November 2021, EJNMMI Research, PubMed Link, DOI Link
A Hydroxypropyl Methylcellulose Film Loaded with AFCP Nanoparticles for Inhibiting Formation of Enamel White Spot Lesions. Z. Zhang, Y. Shi, H. Zheng, Z. Zhou, Z. Wu, D. Shen, Y. Wang, Y. Zhang, Z. Wang, B. Fu, November 2021, International Journal of Nanomedicine, PubMed Link, DOI Link
The Role of Ligand Acid–Base Reaction in the Facile Synthesis of Alkali Metal Neodymium Penta- and Heptafluoride Nanocrystals. X. Wu, J. Tham, A. Chacko, E. Yeow, October 2021, Chemistry of Materials, DOI Link
Semiconducting polymer nano-radiopharmaceutical for combined radio-photothermal therapy of pancreatic tumor. X. Shi, Q. Li, C. Zhang, H. Pei, G. Wang, H. Zhou, L. Fan, K. Yang, B. Jiang, F. Wang, R. Zhu, October 2021, Journal of Nanobiotechnology, PubMed Link, DOI Link
Preclinical study of 212Pb alpha-radioimmunotherapy targeting CD20 in non-Hodgkin lymphoma. S. Durand-Panteix, J. Monteil, M. Sage, A. Garot, M. Clavel, A. Saidi, J. Torgue, M. Cogne, I. Quelven, October 2021, British Journal of Cancer, DOI Link
Transcranial Theranostic Ultrasound for Pre-Planning and Blood-Brain Barrier Opening: A Feasibility Study Using an Imaging Phased Array In Vitro and In Vivo. A. Batts, R. Ji, A. Kline-Schoder, R. Noel, E. Konofagou, October 2021, IEEE Transactions on Biomedical Engineering, PubMed Link, DOI Link
Photo-Driven Delivery of 125I-Labeled Nanomicelles for Nucleus-Targeted Internal Conversion Electron-Based Cancer Therapy. Y. Qin, M. Shen, X. Liu, J. Gu, M. Zhu, X. Yi, October 2021, ACS Applied Materials & Interfaces, PubMed Link, DOI Link
Iron oxide nanoparticles augment the intercellular mitochondrial transfer–mediated therapy. T. Huang, T. Zhang, X. Jiang, A. Li, Y. Su, Q. Bian, H. Wu, R. Lin, N. Li, H. Cao, D. Ling, J. Wang, Y. Tabata, Z. Gu, J. Gao, September 2021, Science Advances, PubMed Link, DOI Link
Convolutional neural network based attenuation correction for 123 I-FP-CIT SPECT with focused striatum imaging. Y. Chen, M. Goorden, F. Beekman, September 2021, Physics in Medicine & Biology, PubMed Link, DOI Link
Multiscale computational modeling of cancer growth using features derived from microCT images. M. Zangooei, R. Margolis, K. Hoyt, September 2021, Scientific Reports, PubMed Link, DOI Link
Fluorescence-Activated Cell Sorting-Radioligand Treated Tissue (FACS-RTT) to Determine the Cellular Origin of Radioactive Signal. Q. Amossé, K. Ceyzériat, S. Tsartsalis, B. Tournier, P. Millet, September 2021, Journal of Visualized Experiments, PubMed Link, DOI Link
Intraosseous Injection of Calcium Phosphate Polymer-Induced Liquid Precursor Increases Bone Density and Improves Early Implant Osseointegration in Ovariectomized Rats. Y. Zhou, Z. Hu, M. Ge, W. Jin, R. Tang, Q. Li, W. Xu, J. Shi, Z. Xie, September 2021, International Journal of Nanomedicine, PubMed Link, DOI Link
Early environmental enrichment and impoverishment differentially affect addiction-related behavioral traits, cocaine-taking, and dopamine D2/3 receptor signaling in a rat model of vulnerability to drug abuse. L. Bellés, A. Dimiziani, F. Herrmann, N. Ginovart, August 2021, Psychopharmacology, PubMed Link, DOI Link
Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides. B. Bavelaar, L. Song, M. Jackson, S. Able, O. Tietz, I. Skaripa-Koukelli, P. Waghorn, M. Gill, R. Carlisle, M. Tarsounas, K. Vallis, August 2021, Molecular pharmaceutics, PubMed Link, DOI Link
Targeted design of a recombinant tracer for SPECT renal imaging. P. Liu, S. Johnson, X. Xie, L. Gao, C. Haney, M. Zhao, J. Jin, August 2021, Theranostics, PubMed Link, DOI Link
Imaging carbonic anhydrase IX as a method for monitoring hypoxia-related radioresistance in preclinical head and neck cancer models. F. Huizing, B. Hoeben, J. Lok, O. Boerman, S. Heskamp, J. Bussink, August 2021, Physics and Imaging in Radiation Oncology, PubMed Link, DOI Link
Concussion/Mild Traumatic Brain Injury (TBI) Induces Brain Insulin Resistance: A Positron Emission Tomography (PET) Scanning Study. S. Sekar, R. Viswas, H. Miranzadeh Mahabadi, E. Alizadeh, H. Fonge, C. Taghibiglou, August 2021, International journal of molecular sciences, PubMed Link, DOI Link
68Ga- and 211At-Labeled RGD Peptides for Radiotheranostics with Multiradionuclides. K. Ogawa, H. Echigo, K. Mishiro, S. Hirata, K. Washiyama, Y. Kitamura, K. Takahashi, K. Shiba, S. Kinuya, August 2021, Molecular pharmaceutics, PubMed Link, DOI Link
A 2-plane micro-computed tomographic alveolar bone measurement approach in mice. R. Catunda, K. Ho, S. Patel, M. Febbraio, August 2021, Imaging Science in Dentistry, DOI Link
Electroacupuncture suppresses glucose metabolism and GLUT-3 expression in medial prefrontal cortical in rats with neuropathic pain. M. Jiang, X. Chen, L. Zhang, W. Liu, X. Yu, Z. Wang, M. Zheng, August 2021, Biological Research, PubMed Link, DOI Link
Reshaping the Inflammatory Environment in Rheumatoid Arthritis Joints by Targeting Delivery of Berberine with Platelet‐Derived Extracellular Vesicles. Q. Ma, J. Bai, J. Xu, H. Dai, Q. Fan, Z. Fei, J. Chu, C. Yao, H. Shi, X. Zhou, L. Bo, C. Wang, August 2021, Advanced NanoBiomed Research, DOI Link
SPECT/CT imaging of inflammation and calcification in human carotid atherosclerosis to identify the plaque at risk of rupture. K. Van der Heiden, H. Barrett, E. Meester, K. van Gaalen, B. Krenning, F. Beekman, E. de Blois, J. de Swart, H. Verhagen, A. van der Lugt, J. Norenberg, M. de Jong, M. Bernsen, F. Gijsen, July 2021, Journal of Nuclear Cardiology, PubMed Link, DOI Link
Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics. H. Rafidi, A. Estevez, G. Ferl, D. Mandikian, S. Stainton, L. Sermeño, S. Williams, A. Kamath, J. Koerber, C. Boswell, July 2021, Molecular Cancer Therapeutics, PubMed Link, DOI Link
Biocompatible nanomicelles for sensitive detection and photodynamic therapy of early-stage cancer. H. Zhou, Z. Qi, P. Pei, W. Shen, Y. Zhang, K. Yang, L. Sun, T. Liu, July 2021, Biomaterials Science, DOI Link
A Novel Radiotracer for Molecular Imaging and Therapy of Gastrin-Releasing Peptide Receptor Positive Prostate Cancer. F. Benard, I. Bratanovic, July 2021, Journal of Nuclear Medicine, PubMed Link, DOI Link
Advances in micro-CT imaging of small animals. D. Clark, C. Badea, July 2021, Physica Medica, PubMed Link, DOI Link
211 At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer. X. Shi, Q. Li, L. Zhang, M. Hanyu, L. Xie, K. Hu, K. Nagatsu, C. Zhang, Z. Wu, F. Wang, M. Zhang, K. Yang, R. Zhu, July 2021, Bioconjugate Chemistry, PubMed Link, DOI Link
Diagnostic Radionuclides Labeled on Biomimetic Nanoparticles for Enhanced Follow-Up Photothermal Therapy of Cancer. X. Yi, M. Shen, X. Liu, J. Gu, Z. Jiang, L. Xu, K. Yang, July 2021, Advanced Healthcare Materials, PubMed Link, DOI Link
Simultaneous SPECT imaging with 123I and 125I – a practical approach to assessing a drug and its carrier at the same time with dual imaging. Z. Nosrati, P. Esquinas, C. Rodríguez-Rodríguez, T. Tran, A. Maharaj, K. Saatchi, U. Häfeli, July 2021, International Journal of Pharmaceutics, PubMed Link, DOI Link
Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration. M. Ramos, D. Mandikian, L. Sermeño, A. King, A. Dent, J. Ho, S. Ulufatu, T. Lombana, C. Spiess, M. Go, S. Yu, A. Kamath, G. Ferl, C. Boswell, July 2021, Molecular Cancer Therapeutics, PubMed Link, DOI Link
Evaluation of different grafting materials for alveolar cleft repair in the context of orthodontic tooth movement in rats. S. Möhlhenrich, K. Kniha, Z. Magnuska, B. Hermanns-Sachweh, F. Gremse, F. Hölzle, G. Danesh, A. Modabber, June 2021, Scientific Reports, PubMed Link, DOI Link
Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts. A. Gasiorek, E. Dobosz, B. Potempa, I. Ciaston, M. Wilamowski, Z. Oruba, R. Lamont, J. Jura, J. Potempa, J. Koziel, June 2021, mBio, PubMed Link, DOI Link
A Model System to Explore the Detection Limits of Antibody-Based Immuno-SPECT Imaging of Exclusively Intranuclear Epitopes. M. Veal, G. Dias, V. Kersemans, D. Sneddon, S. Faulkner, B. Cornelissen, June 2021, Journal of Nuclear Medicine, PubMed Link, DOI Link
Nasal Septum Deviation as the Consequence of BMP-Controlled Changes to Cartilage Properties. P. Baddam, D. Young, G. Dunsmore, C. Nie, F. Eaton, S. Elahi, J. Jovel, A. Adesida, A. Dufour, D. Graf, June 2021, Frontiers in cell and developmental biology, PubMed Link, DOI Link
CPPs to the Test: Effects on Binding, Uptake and Biodistribution of a Tumor Targeting Nanobody. E. Collado Camps, S. van Lith, C. Frielink, J. Lankhof, I. Dijkgraaf, M. Gotthardt, R. Brock, June 2021, Pharmaceuticals, DOI Link
Novel treatment for glioblastoma delivered by a radiation responsive and radiopaque hydrogel. M. Bouché, Y. Dong, S. Sheikh, K. Taing, D. Saxena, J. Hsu, M. Chen, R. Salinas, H. Song, J. Burdick, J. Dorsey, D. Cormode, June 2021, ACS Biomaterials Science and Engineering, PubMed Link, DOI Link
Characterization of Intrinsically Radiolabeled Poly(lactic- co-glycolic acid) Nanoparticles for ex Vivo Autologous Cell Labeling and in Vivo Tracking. M. Krekorian, G. Sandker, K. Cortenbach, O. Tagit, N. Van Riessen, R. Raavé, M. Srinivas, C. Figdor, S. Heskamp, E. Aarntzen, June 2021, Bioconjugate Chemistry, PubMed Link, DOI Link
CUB domain containing protein 1 (CDPC1) is a target for radioligand therapy in castration resistant prostate cancer. N. Zhao, K. Trepka, Y. Wang, S. Chopra, N. Hooshdaran, H. Kim, J. Zhuo, S. Lim, J. Yang, K. Leung, E. Egusa, L. Zhang, A. Foye, J. Chou, F. Feng, E. Small, J. Wells, R. Aggarwal, M. Evans, June 2021, bioRxiv, DOI Link
Efficient Monte-Carlo based system modelling for image reconstruction in preclinical pinhole SPECT. M. Nguyen, M. Goorden, R. Ramakers, F. Beekman, June 2021, Physics in Medicine and Biology, DOI Link
Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells. Q. Liu, Y. Luo, Y. Zhao, P. Xiang, J. Zhu, W. Jing, W. Jin, M. Chen, R. Tang, H. Yu, June 2021, Bioactive Materials, DOI Link
Arteriovenous fistula-induced cardiac remodeling shows cardioprotective features in mice. S. Lee, S. Thorn, N. Guerrera, L. Gonzalez, R. Taniguchi, J. Langford, A. Sinusas, A. Dardik, May 2021, JVS: Vascular Science, DOI Link
Augmenting a dynamic hip screw with a calcium sulfate/hydroxyapatite biomaterial. J. Kok, A. Širka, Y. Liu, . Tarasevičius, J. Belickas, M. Tägil, L. Lidgren, H. Isaksson, D. Raina, May 2021, Medical Engineering and Physics, PubMed Link, DOI Link
Topographic features of nano-pores within the osteochondral interface and their effects on transport properties –a 3D imaging and modeling study. B. Pouran, A. Raoof, D. de Winter, V. Arbabi, R. Bleys, F. Beekman, A. Zadpoor, J. Malda, H. Weinans, May 2021, Journal of Biomechanics, PubMed Link, DOI Link
Heterotypic tumor models through freeform printing into photostabilized granular microgels. T. Molley, G. Jalandhra, S. Nemec, A. Tiffany, A. Patkunarajah, K. Poole, B. Harley, T. Hung, K. Kilian, May 2021, Biomaterials Science, PubMed Link, DOI Link
An Effective and Reliable Methodology for Deep Machine Learning Application in Caries Detection (Vol. , pp. 1-16) [Computer software]. Y. Huang, S. Lee, May 2021, DOI Link
Novel human antibodies to insulin growth factor 2 receptor (Igf2r) for radioimmunoimaging and therapy of canine and human osteosarcoma. J. Broqueza, C. Prabaharan, S. Andrahennadi, K. Allen, R. Dickinson, V. Macdonald-Dickinson, E. Dadachova, M. Uppalapati, May 2021, Cancers, DOI Link
3D-printed saw guides for lower arm osteotomy, a comparison between a synthetic CT and CT-based workflow. K. Willemsen, M. Ketel, F. Zijlstra, M. Florkow, R. Kuiper, B. van der Wal, H. Weinans, B. Pouran, F. Beekman, P. Seevinck, R. Sakkers, April 2021, 3D Printing in Medicine, PubMed Link, DOI Link
The Chromatin Regulator Ankrd11 Controls Palate and Cranial Bone Development. D. Roth, P. Baddam, H. Lin, M. Vidal-García, J. Aponte, S. De Souza, D. Godziuk, A. Watson, T. Footz, N. Schachter, S. Egan, B. Hallgrímsson, D. Graf, A. Voronova, April 2021, Frontiers in Cell and Developmental Biology, DOI Link
Decorating sdabs with chelators: Effect of conjugation on biodistribution and functionality. H. Baudhuin, J. Puttemans, H. Hanssens, P. Vanwolleghem, S. Hernot, G. Raes, C. Xavier, T. Lahoutte, P. Debie, April 2021, Pharmaceuticals, PubMed Link, DOI Link
A simple, open and extensible gating Control unit for cardiac and respiratory synchronisation control in small animal MRI and demonstration of its robust performance in steady-state maintained CINE-MRI. S. Gilchrist, P. Kinchesh, V. Kersemans, J. Beech, D. Allen, M. Brady, B. Vojnovic, J. Schneider, J. Miller, S. Smart, April 2021, Magnetic Resonance Imaging, PubMed Link, DOI Link
Impact of a CD36 inhibitor on Porphyromonas gingivalis mediated atherosclerosis. U. Rekhi, R. Catunda, M. Alexiou, M. Sharma, A. Fong, M. Febbraio, April 2021, Archives of Oral Biology, PubMed Link, DOI Link
TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss. G. Li, Q. Zhang, Z. Liu, H. Shen, Y. Zhu, Z. Zhou, W. Ding, S. Han, J. Zhou, R. Ou, M. Luo, S. Liu, April 2021, Cancer Cell International, PubMed Link, DOI Link
Femoral strength and strains in sideways fall: Validation of finite element models against bilateral strain measurements. J. Kok, L. Grassi, A. Gustafsson, H. Isaksson, April 2021, Journal of Biomechanics, PubMed Link, DOI Link
Iodinated BSA Nanoparticles for Macrophage-Mediated CT Imaging and Repair of Gastritis. Y. Wu, J. Gu, S. Zhang, Y. Gu, J. Ma, Y. Wang, L. Zhang, Y. Wang, April 2021, Analytical Chemistry, PubMed Link, DOI Link
Preparation of Heat-Denatured Macroaggregated Albumin for Biomedical Applications Using a Microfluidics Platform. T. Esposito, H. Stütz, C. Rodríguez-Rodríguez, M. Bergamo, L. Charles, R. Geczy, C. Blackadar, J. Kutter, K. Saatchi, U. Häfeli, April 2021, ACS Biomaterials Science and Engineering, PubMed Link, DOI Link
Radionuclide labeled gold nanoclusters boost effective anti-tumor immunity for augmented radio-immunotherapy of cancer. P. Pei, W. Shen, H. Zhou, Y. Sun, J. Zhong, T. Liu, K. Yang, April 2021, Nano Today, DOI Link
Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm. J. Toczek, P. Boodagh, N. Sanzida, M. Ghim, M. Salarian, K. Gona, G. Kukreja, S. Rajendran, L. Wei, J. Han, J. Zhang, J. Jung, M. Graham, X. Liu, M. Sadeghi, April 2021, Theranostics, PubMed Link, DOI Link
BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin–YAP Signaling Axis. Y. Wang, M. Zhao, W. Li, Y. Yang, Z. Zhang, R. Ma, M. Wu, April 2021, Frontiers in Cell and Developmental Biology, DOI Link
BiVO4/[email protected] superparticles for tumor multimodal imaging and synergistic therapy. Z. Wang, G. Wang, T. Kang, S. Liu, L. Wang, H. Zou, Y. Chong, Y. Liu, March 2021, Journal of Nanobiotechnology, PubMed Link, DOI Link
Ginkgolide B monotherapy reverses osteoporosis by regulating oxidative stress-mediated bone homeostasis. C. Lee, H. Lin, B. Wang, A. Wang, R. Shin, S. Cheung, O. Lee, March 2021, Free Radical Biology and Medicine, PubMed Link, DOI Link
Real-time positron emission tomography evaluation of topotecan brain kinetics after ultrasound-mediated blood–brain barrier permeability. A. Molotkov, P. Carberry, M. Dolan, S. Joseph, S. Idumonyi, S. Oya, J. Castrillon, E. Konofagou, M. Doubrovin, G. Lesser, F. Zanderigo, A. Mintz, March 2021, Pharmaceutics, DOI Link
Dopamine D2/3 Receptor Availabilities and Evoked Dopamine Release in Striatum Differentially Predict Impulsivity and Novelty Preference in Roman High- and Low-Avoidance Rats. L. Bellés, A. Dimiziani, S. Tsartsalis, P. Millet, F. Herrmann, N. Ginovart, March 2021, International Journal of Neuropsychopharmacology, PubMed Link, DOI Link
Variation in cross-sectional shape and biomechanical properties of the bat humerus under Wolff’s law. C. López-Aguirre, L. Wilson, D. Koyabu, V. Tu, S. Hand, March 2021, Anatomical Record, PubMed Link, DOI Link
Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer’s disease. K. Ceyzériat, Y. Gloria, S. Tsartsalis, C. Fossey, T. Cailly, F. Fabis, P. Millet, B. Tournier, March 2021, Brain Communications, DOI Link
Positron range-free and multi-isotope tomography of positron emitters. F. Beekman, C. Kamphuis, S. Koustoulidou, R. Ramakers, M. Goorden, March 2021, Physics in Medicine and Biology, PubMed Link, DOI Link
Automatic attenuation map estimation from SPECT data only for brain perfusion scans using convolutional neural networks. Y. Chen, M. Goorden, F. Beekman, March 2021, Physics in Medicine and Biology, PubMed Link, DOI Link
Establishing a new alveolar cleft model in rats to investigate the influence of jaw reconstructions on orthodontic tooth movement. S. Möhlhenrich, M. Heitzer, Z. Magnuska, F. Gremse, S. Chhatwani, G. Danesh, F. Hölzle, A. Modabber, March 2021, Annals of Anatomy, PubMed Link, DOI Link
Design of PSMA ligands with modifications at the inhibitor part: an approach to reduce the salivary gland uptake of radiolabeled PSMA inhibitors?. V. Felber, M. Valentin, H. Wester, February 2021, EJNMMI Radiopharmacy and Chemistry, DOI Link
The design and preclinical evaluation of a single‐label bimodal nanobody tracer for image‐guided surgery. P. Debie, N. Declerck, D. van Willigen, C. Huygen, B. De Sloovere, L. Mateusiak, J. Bridoux, J. Puttemans, N. Devoogdt, F. van Leeuwen, S. Hernot, February 2021, Biomolecules, PubMed Link, DOI Link
Collagen-Induced Temporomandibular Joint Arthritis Juvenile Rat Animal Model. J. Crossman, H. Lai, M. Kulka, N. Jomha, P. Flood, T. El-Bialy, February 2021, Tissue Engineering – Part C: Methods, PubMed Link, DOI Link
An Experimental Study on [125I]I-pHLIP (Var7) for SPECT/CT Imaging of an MDA-MB-231 Triple-Negative Breast Cancer Mouse Model by Targeting the Tumor Microenvironment. M. Yu, Y. Sun, G. Yang, Z. Wang, February 2021, Molecular Imaging, PubMed Link, DOI Link
Neural crest-specific loss of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction and disordered breathing, modeling obstructive sleep apnea. P. Baddam, V. Biancardi, D. Roth, F. Eaton, C. Thereza-Bussolaro, R. Mandal, D. Wishart, A. Barr, J. MacLean, C. Flores-Mir, S. Pagliardini, D. Graf, February 2021, DMM Disease Models and Mechanisms, PubMed Link, DOI Link
An anatomical thermal 3d model in preclinical research: Combining ct and thermal images. F. Schollemann, C. Pereira, S. Rosenhain, A. Follmann, F. Gremse, F. Kiessling, M. Czaplik, M. de Souza, February 2021, Sensors (Switzerland), PubMed Link, DOI Link
Human monoclonal antibodies against Staphylococcus aureus surface. L. de Vor, B. van Dijk, K. van Kessel, J. Kavanaugh, C. de Haas, C. Aerts, M. Viveen, E. Boel, A. Fluit, J. Kwiecinski, G. Krijger, M. Ramakers, F. Beekman, E. Dadachova, M. GEH Lam, H. Charles Vogely, B. van der Wal, J. van Strijp, A. Horswill, H. Weinans, February 2021, bioRxiv
A system-agnostic, adaptable and extensible animal support cradle system for cardio-respiratory-synchronised, and other, multi-modal imaging of small animals. V. Kersemans, S. Gilchrist, P. Allen, S. Wallington, P. Kinchesh, J. Prentice, M. Tweedie, J. Warner, S. Smart, February 2021, Tomography, PubMed Link, DOI Link
On the ability of experimental impact measures to predict tooth injuries in an ex vivo swine model. K. Houg, K. Adanty, S. MacGillivray, L. McAllister, L. Levin, M. Alexiou, D. Graf, D. Romanyk, C. Dennison, February 2021, Dental Traumatology, PubMed Link, DOI Link
Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid. M. Kobayashi, A. Mizutani, T. Okamoto, Y. Muranaka, K. Nishi, R. Nishii, N. Shikano, T. Nakanishi, I. Tamai, E. Kleinerman, K. Kawai, February 2021, Nuclear Medicine and Biology, PubMed Link, DOI Link
A novel mouse model of radiation-induced cardiac injury reveals biological and radiological biomarkers of cardiac dysfunction with potential clinical relevance. A. Dreyfuss, D. Goia, K. Shoniyozov, S. Shewale, A. Velalopoulou, S. Mazzoni, H. Avgousti, S. Metzler, P. Bravo, S. Feigenberg, B. Ky, I. Verginadis, C. Koumenis, February 2021, Clinical Cancer Research, PubMed Link, DOI Link
Versatile labeling of multiple radionuclides onto a nanoscale metal-organic framework for tumor imaging and radioisotope therapy. Y. Tao, Y. Sun, K. Shi, P. Pei, F. Ge, K. Yang, T. Liu, February 2021, Biomaterials Science, PubMed Link, DOI Link
Cyclodextrin-based host-guest complexes loaded with regorafenib for colorectal cancer treatment. H. Bai, J. Wang, C. Phan, Q. Chen, X. Hu, G. Shao, J. Zhou, L. Lai, G. Tang, February 2021, Nature Communications, PubMed Link, DOI Link
Highly tumor-specific and long-acting iodine-131 microbeads for enhanced treatment of hepatocellular carcinoma with low-dose radio-chemoembolization. W. Lu, S. Song, Y. Qian, Q. Liu, P. Li, Y. Han, J. Zhang, J. Xu, J. Sun, A. Wu, February 2021, ACS Nano, PubMed Link, DOI Link
Characterization of cardiovascular injury in mice following partial-heart irradiation with clinically relevant dose and fractionation. C. Lee, J. Lee, A. Daniel, M. Holbrook, S. Hasapis, A. Wright, J. Brownstein, L. Da Silva Campos, Y. Ma, L. Mao, D. Abraham, C. Badea, D. Kirsch, February 2021, Radiotherapy and Oncology, PubMed Link, DOI Link
89 Zr‐Labeled Domain Ii‐Specific Scfv‐Fc Immunopet Probe for Imaging Epidermal Growth Factor Receptor in Vivo. E. Alizadeh, K. Ahmed, V. Solomon, V. Gaja, W. Bernhard, A. Makhlouf, C. Gonzalez, K. Barreto, A. Casaco, C. Geyer, H. Fonge, February 2021, Cancers, PubMed Link, DOI Link
Precision Medicine in Ossiculoplasty. P. Mukherjee, K. Cheng, J. Chung, S. Grieve, M. Solomon, G. Wallace, February 2021, Otology & neurotology, PubMed Link, DOI Link
Site-specific dual-labeling of a vhh with a chelator and a photosensitizer for nuclear imaging and targeted photodynamic therapy of egfr-positive tumors. E. Renard, E. Camps, C. Canovas, A. Kip, M. Gotthardt, M. Rijpkema, F. Denat, V. Goncalves, S. van Lith, January 2021, Cancers, PubMed Link, DOI Link
Modulation of the Pharmacokinetics of a Radioligand Targeting Carbonic Anhydrase-IX with Albumin-Binding Moieties. S. Iikuni, Y. Okada, Y. Shimizu, H. Watanabe, M. Ono, January 2021, Molecular Pharmaceutics, PubMed Link, DOI Link
The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type 2 immunity-independent inhibition of food intake. H. van der Zande, M. Gonzalez, K. de Ruiter, R. Wilbers, N. García-Tardón, M. van Huizen, K. van Noort, L. Pelgrom, J. Lambooij, A. Zawistowska-Deniziak, F. Otto, A. Ozir-Fazalalikhan, D. van Willigen, M. Welling, J. Poles, F. van Leeuwen, C. Hokke, A. Schots, M. Yazdanbakhsh, P. Loke, B. Guigas, January 2021, FASEB Journal, PubMed Link, DOI Link
Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton. J. Smeeton, N. Natarajan, A. Kumar, T. Miyashita, P. Baddam, P. Fabian, D. Graf, J. Crump, January 2021, Development (Cambridge), PubMed Link, DOI Link
Effect of 5-HT2A receptor antagonism on levels of D2/3 receptor occupancy and adverse behavioral side-effects induced by haloperidol: a SPECT imaging study in the rat. S. Tsartsalis, B. Tournier, Y. Gloria, P. Millet, N. Ginovart, January 2021, Translational Psychiatry, PubMed Link, DOI Link
Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration. L. Wu, L. Wu, J. Wu, J. Sun, Z. He, C. Rodríguez-Rodríguez, K. Saatchi, L. Dailey, U. Häfeli, D. Cun, M. Yang, January 2021, ACS Applied Materials and Interfaces, PubMed Link, DOI Link
Mtu1 defects are correlated with reduced osteogenic differentiation. Q. He, Q. Zhao, Q. Li, R. Pan, X. Li, Y. Chen, January 2021, Cell Death and Disease, PubMed Link, DOI Link
In vitro and in vivo evaluation of [125/123I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([125/123I]-OI5V) as a potential sigma-1 receptor ligand for SPECT. T. Shigeno, T. Kozaka, Y. Kitamura, K. Ogawa, J. Taki, S. Kinuya, K. Shiba, January 2021, Annals of Nuclear Medicine, PubMed Link, DOI Link
Skin protective and regenerative effects of RM191A, a novel superoxide dismutase mimetic. A. Shariev, S. Menounos, A. Laos, P. Laxman, D. Lai, S. Hua, A. Zinger, C. McRae, L. Casbolt, V. Combes, G. Smith, T. Hung, K. Dixon, P. Thordarson, R. Mason, A. Das, January 2021, Redox Biology, DOI Link
Interventional nuclear medicine: “click” chemistry as an: In vivo targeting strategy for imaging microspheres and bacteria. M. Welling, N. Duszenko, D. Van Willigen, A. Hensbergen, T. Buckle, D. Rietbergen, M. Roestenberg, F. Van Leeuwen, January 2021, Biomaterials Science, PubMed Link, DOI Link
Photosensitizer-based multimodal PSMA-targeting ligands for intraoperative detection of prostate cancer. Y. Derks, M. Rijpkema, H. Amatdjais-Groenen, A. Kip, G. Franssen, J. Michiel Sedelaar, D. Somford, M. Simons, P. Laverman, M. Gotthardt, D. Löwik, S. Lütje, S. Heskamp, January 2021, Theranostics, PubMed Link, DOI Link

2020

Bone-Seeking Albumin-Nanomedicine for in Vivo Imaging and Therapeutic Monitoring. Z. Chen, H. Yu, W. Lu, J. Shen, Y. Wang, Y. Wang, December 2020, ACS Biomaterials Science and Engineering, PubMed Link, DOI Link
Capabilities of multi-pinhole SPECT with two stationary detectors for in vivo rat imaging. J. Janssen, J. Hoffmann, T. Kanno, N. Nose, J. Grunz, M. Onoguchi, X. Chen, C. Lapa, A. Buck, T. Higuchi, December 2020, Scientific Reports, PubMed Link, DOI Link
Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer. V. Solomon, E. Alizadeh, W. Bernhard, A. Makhlouf, S. Hartimath, W. Hill, A. El-Sayed, K. Barreto, C. Geyer, H. Fonge, December 2020, Scientific Reports, PubMed Link, DOI Link
Phylogeny and foraging behaviour shape modular morphological variation in bat humeri. C. López-Aguirre, S. Hand, D. Koyabu, V. Tu, L. Wilson, December 2020, Journal of Anatomy, PubMed Link, DOI Link
Early detection in a mouse model of pancreatic cancer by imaging DNA damage response signaling. J. Knight, J. Torres, R. Goldin, M. Mosley, G. Dias, L. Bravo, V. Kersemans, P. Allen, S. Mukherjee, S. Smart, B. Cornelissen, December 2020, Journal of Nuclear Medicine, PubMed Link, DOI Link
212Pb α-radioimmunotherapy targeting CD38 in multiple myeloma: A preclinical study. I. Quelven, J. Monteil, M. Sage, A. Saidi, J. Mounier, A. Bayout, J. Garrier, M. Cogne, S. Durand-Panteix, December 2020, Journal of Nuclear Medicine, PubMed Link, DOI Link
Thallium-201 Imaging in Intact Olfactory Sensory Neurons with Reduced Pre-Synaptic Inhibition In Vivo. H. Shiga, H. Wakabayashi, K. Washiyama, T. Noguchi, T. Hiromasa, S. Miyazono, M. Kumai, K. Ogawa, J. Taki, S. Kinuya, T. Miwa, December 2020, Molecular Neurobiology, DOI Link
Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers. A. Molotkov, N. Bhatt, M. Doubrovin, J. Castrillon, C. Massa, A. Gerber, J. D’Armiento, M. Goldklang, A. Mintz, December 2020, Molecular Biomedicine, DOI Link
In vivo absolute quantification of striatal and extrastriatal D2/3 receptors with [123I]epidepride SPECT. S. Tsartsalis, B. Tournier, P. Millet, December 2020, EJNMMI Research, PubMed Link, DOI Link
Serial examination of cardiac function and perfusion in growing rats using SPECT/CT for small animals. T. Hiromasa, J. Taki, H. Wakabayashi, A. Inaki, K. Okuda, T. Shibutani, K. Shiba, S. Kinuya, December 2020, Scientific Reports, PubMed Link, DOI Link
Dietary and body-mass reconstruction of the Miocene neotropical bat Notonycteris magdalenensis (Phyllostomidae) from la Venta, Colombia. C. López-Aguirre, N. Czaplewski, A. Link, M. Takai, S. Hand, December 2020, Paleobiology, DOI Link
Bone tumor–targeted delivery of theranostic 195mPt-bisphosphonate complexes promotes killing of metastatic tumor cells. R. Nadar, G. Franssen, N. Van Dijk, K. Codee-van der Schilden, M. de Weijert, E. Oosterwijk, M. Iafisco, N. Margiotta, S. Heskamp, J. van den Beucken, S. Leeuwenburgh, December 2020, Materials Today Bio, PubMed Link, DOI Link
A universal dual mechanism immunotherapy for the treatment of influenza virus infections. X. Liu, B. Zhang, Y. Wang, H. Haymour, F. Zhang, L. Xu, M. Srinivasarao, P. Low, December 2020, Nature Communications, PubMed Link, DOI Link
3D optical/CT as a preclinical companion imaging platform for glioblastoma drug development. A. Molotkov, M. Doubrovin, N. Bhatt, F. Hsu, A. Beserra, R. Chopra, A. Mintz, December 2020, Drug Delivery, PubMed Link, DOI Link
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity. R. Nadar, K. Farbod, K. der Schilden, L. Schlatt, B. Crone, N. Asokan, A. Curci, M. Brand, M. Bornhaeuser, M. Iafisco, N. Margiotta, U. Karst, S. Heskamp, O. Boerman, J. van den Beucken, S. Leeuwenburgh, December 2020, Scientific Reports, PubMed Link, DOI Link
Targeting glutamine metabolism slows soft tissue sarcoma growth. P. Lee, D. Malik, N. Perkons, P. Huangyang, S. Khare, S. Rhoades, Y. Gong, M. Burrows, J. Finan, I. Nissim, T. Gade, A. Weljie, M. Simon, December 2020, Nature Communications, PubMed Link, DOI Link
Development of gold nanorods conjugated with radiolabeled anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibody as single-photon emission computed tomography/photoacoustic dual-imaging probes targeting HER2-positive tumors. N. Ding, K. Sano, Y. Shimizu, H. Watanabe, T. Namita, T. Shiina, M. Ono, H. Saji, December 2020, Biological and Pharmaceutical Bulletin, PubMed Link, DOI Link
Microstructural volumetric analysis of the jaw following dental implantation under systemic bisphosphonate delivery: An in vivo and ex vivo rat study. K. Kniha, A. Bock, F. Peters, Z. Magnuska, F. Gremse, S. Möhlhenrich, F. Hölzle, A. Modabber, November 2020, Journal of Periodontology, PubMed Link, DOI Link
Ischial tuberosity: new donor site for bone grafts in animal cleft research. S. Möhlhenrich, K. Kniha, Z. Magnuska, F. Gremse, F. Peters, G. Danesh, F. Hölzle, A. Modabber, November 2020, Scientific Reports, PubMed Link, DOI Link
Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems. T. Tran, P. Bønløkke, C. Rodríguez-Rodríguez, Z. Nosrati, P. Esquinas, N. Borkar, J. Plum, S. Strindberg, S. Karagiozov, T. Rades, A. Müllertz, K. Saatchi, U. Häfeli, November 2020, Journal of Controlled Release, PubMed Link, DOI Link
Proof of concept study for increasing tenascin-C-targeted drug delivery to tumors previously subjected to therapy: X-irradiation increases tumor uptake. A. Sugyo, A. Tsuji, H. Sudo, K. Takano, M. Kusakabe, T. Higashi, November 2020, Cancers, PubMed Link, DOI Link
Noninvasive Monitoring of Glycemia-Induced Regulation of GLP-1R Expression in Murine and Human Islets of Langerhans. M. Buitinga, C. Cohrs, W. Eter, L. Claessens-Joosten, C. Frielink, D. Bos, G. Sandker, M. Brom, S. Speier, M. Gotthardt, November 2020, Diabetes, PubMed Link, DOI Link
Nimotuzumab site-specifically labeled with89zr and225ac using spytag/spycatcher for pet imaging and alpha particle radioimmunotherapy of epidermal growth factor receptor positive cancers. V. Solomon, K. Barreto, W. Bernhard, E. Alizadeh, P. Causey, R. Perron, D. Gendron, M. Alam, A. Carr, C. Geyer, H. Fonge, November 2020, Cancers, PubMed Link, DOI Link
EXIRAD-HE: Multi-pinhole high-resolution ex vivo imaging of high-energy isotopes. M. Nguyen, M. Goorden, F. Beekman, November 2020, Physics in Medicine and Biology, DOI Link
Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis. T. Ho, A. Nasti, A. Seki, T. Komura, H. Inui, T. Kozaka, Y. Kitamura, K. Shiba, T. Yamashita, T. Yamashita, E. Mizukoshi, K. Kawaguchi, T. Wada, M. Honda, S. Kaneko, Y. Sakai, November 2020, Journal for ImmunoTherapy of Cancer, PubMed Link, DOI Link
[18F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging. F. Guibbal, S. Hopkins, A. Pacelli, P. Isenegger, M. Mosley, J. Torres, G. Dias, D. Mahaut, R. Hueting, V. Gouverneur, B. Cornelissen, October 2020, Molecular Imaging and Biology, PubMed Link, DOI Link
Extensive preclinical evaluation of lutetium-177-labeled PSMA-specific tracers for prostate cancer radionuclide therapy. E. Ruigrok, N. van Vliet, S. Dalm, E. de Blois, D. van Gent, J. Haeck, C. de Ridder, D. Stuurman, M. Konijnenberg, W. van Weerden, M. de Jong, J. Nonnekens, October 2020, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
Disturbed gut microbiota and bile homeostasis in Giardia -infected mice contributes to metabolic dysregulation and growth impairment. A. Riba, K. Hassani, A. Walker, N. van Best, D. von Zeschwitz, T. Anslinger, N. Sillner, S. Rosenhain, D. Eibach, O. Maiga-Ascofaré, U. Rolle-Kampczyk, M. Basic, A. Binz, S. Mocek, B. Sodeik, R. Bauerfeind, A. Mohs, C. Trautwein, F. Kiessling, J. May, M. Klingenspor, F. Gremse, P. Schmitt-Kopplin, A. Bleich, N. Torow, M. von Bergen, M. Hornef, October 2020, Science Translational Medicine, PubMed Link, DOI Link
111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis. K. Fujiwara, A. Tsuji, H. Sudo, A. Sugyo, H. Akiba, H. Iwanari, O. Kusano-Arai, K. Tsumoto, T. Momose, T. Hamakubo, T. Higashi, October 2020, Annals of Nuclear Medicine, PubMed Link, DOI Link
Histological and molecular characterization of the growing nasal septum in mice. P. Baddam, T. Kung, A. Adesida, D. Graf, October 2020, Journal of Anatomy, PubMed Link, DOI Link
Engineering NIR-IIb fluorescence of Er-based lanthanide nanoparticles for through-skull targeted imaging and imaging-guided surgery of orthotopic glioma. F. Ren, H. Liu, H. Zhang, Z. Jiang, B. Xia, C. Genevois, T. He, M. Allix, Q. Sun, Z. Li, M. Gao, October 2020, Nano Today, DOI Link
In Vivo Evaluation of Indium-111–Labeled 800CW as a Necrosis-Avid Contrast Agent. M. Stroet, E. de Blois, D. Stuurman, C. de Ridder, J. Haeck, Y. Seimbille, L. Mezzanotte, M. de Jong, C. Löwik, K. Panth, October 2020, Molecular Imaging and Biology, DOI Link
Analysis of the bone fracture targeting properties of osteotropic ligands. J. Nielsen, S. Low, N. Ramseier, R. Hadap, N. Young, M. Wang, P. Low, October 2020, Journal of Controlled Release, PubMed Link, DOI Link
The clinical utilities of multi-pinhole single photon emission computed tomography. I. Ozsahin, L. Chen, A. Könik, M. King, F. Beekman, G. Mok, October 2020, Quantitative Imaging in Medicine and Surgery, DOI Link
Decreased gas-diffusion electrode porosity due to increased electrocatalyst loading leads to diffusional limitations in cathodic H2O2 electrosynthesis. E. Murawski, N. Kananizadeh, S. Lindsay, A. Rao, S. Popat, September 2020, Journal of Power Sources, DOI Link
Improved Noninvasive In Vivo Tracking of AAV-9 Gene Therapy Using the Perchlorate-Resistant Sodium Iodide Symporter from Minke Whale. S. Concilio, L. Suksanpaisan, L. Pham, K. Peng, S. Russell, September 2020, Molecular Therapy, PubMed Link, DOI Link
Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles. I. Biancacci, Q. Sun, D. Möckel, F. Gremse, S. Rosenhain, F. Kiessling, M. Bartneck, Q. Hu, M. Thewissen, G. Storm, W. Hennink, Y. Shi, C. Rijcken, T. Lammers, A. Sofias, September 2020, Journal of Controlled Release, PubMed Link, DOI Link
[131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma. M. Kobayashi, A. Mizutani, K. Nishi, Y. Muranaka, R. Nishii, N. Shikano, T. Nakanishi, I. Tamai, E. Kleinerman, K. Kawai, September 2020, Nuclear Medicine and Biology, PubMed Link, DOI Link
Multimodal CEA-targeted image-guided colorectal cancer surgery using 111in-labeled SGM-101. J. de Gooyer, F. Elekonawo, D. Bos, R. van der Post, A. Pèlegrin, B. Framery, F. Cailler, A. Vahrmeijer, J. de Wilt, M. Rijpkema, September 2020, Clinical Cancer Research, PubMed Link, DOI Link
Therapeutic Efficacy of 213 Bi-labeled sdAbs in a Preclinical Model of Ovarian Cancer. Y. Dekempeneer, V. Caveliers, M. Ooms, D. Maertens, M. Gysemans, T. Lahoutte, C. Xavier, Q. Lecocq, K. Maes, P. Covens, B. Miller, F. Bruchertseifer, A. Morgenstern, T. Cardinaels, M. D’Huyvetter, September 2020, Molecular Pharmaceutics, PubMed Link, DOI Link
Freeform printing of heterotypic tumor models within cell-laden microgel matrices. T. Molley, G. Jalandhra, S. Nemec, A. Tiffany, B. Harley, T. Hung, K. Kilian, August 2020, bioRxiv
Evaluating Microelectrode Arrays in Peripheral Nerve Using Micro Computed Tomography. R. Frederick, R. Margolis, K. Hoyt, S. Cogan, August 2020, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, DOI Link
Super Spatial Resolution (SSR) method for small animal SPECT imaging: A Monte Carlo study. R. Massari, A. D’Elia, A. Soluri, A. Soluri, August 2020, Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, DOI Link
Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency. H. Bai, N. Sadaghianloo, J. Gorecka, S. Liu, S. Ono, A. Ramachandra, S. Bonnet, N. Mazure, S. Declemy, J. Humphrey, A. Dardik, August 2020, Science Translational Medicine, PubMed Link, DOI Link
Haemophilus influenzae persists in biofilm communities in a smoke-exposed ferret model of COPD. B. Hunt, D. Stanford, X. Xu, J. Li, A. Gaggar, S. Rowe, S. Raju, W. Swords, August 2020, ERJ Open Research, PubMed Link, DOI Link
An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: Mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells. M. Gill, M. Walker, S. Able, O. Tietz, A. Lakshminarayanan, R. Anderson, R. Chalk, A. El-Sagheer, T. Brown, J. Thomas, K. Vallis, August 2020, Chemical Science, DOI Link
nkx3.2 mutant zebrafish accommodate jaw joint loss through a phenocopy of the head shapes of Paleozoic jawless fish. T. Miyashita, P. Baddam, J. Smeeton, A. Oel, N. Natarajan, B. Gordon, A. Palmer, J. Crump, D. Graf, W. Allison, August 2020, The Journal of experimental biology, PubMed Link, DOI Link
Targeted photodynamic therapy selectively kills activated fibroblasts in experimental arthritis. D. Dorst, M. Rijpkema, M. Boss, B. Walgreen, M. Helsen, D. Bos, M. Brom, C. Klein, P. Laverman, P. Van Der Kraan, M. Gotthardt, M. Koenders, M. Buitinga, July 2020, Revmatologiia (Bulgaria), PubMed Link, DOI Link
Why the preclinical imaging field needs nuclear medicine technologists and radiographers?. J. Dillenseger, P. Choquet, E. Snay, P. Fragoso Costa, July 2020, European Journal of Hybrid Imaging, PubMed Link, DOI Link
Bioimaging and Biodistribution of the Metal-Ion-Controlled Self-Assembly of PYY3–36 Studied by SPECT/CT. P. Kalomoiri, C. Rodríguez-Rodríguez, K. Sørensen, M. Bergamo, K. Saatchi, U. Häfeli, K. Jensen, July 2020, ChemBioChem, PubMed Link, DOI Link
Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer. A. Moroz, Y. Wang, J. Sharib, J. Wei, N. Zhao, Y. Huang, Z. Chen, A. Martinko, J. Zhuo, S. Lim, L. Zhang, Y. Seo, S. Carlin, K. Leung, E. Collisson, K. Kirkwood, J. Wells, M. Evans, July 2020, Clinical Cancer Research, PubMed Link, DOI Link
[email protected] Nanorods with Enhanced Charge Separation Efficiency for Multimodal Imaging and Synergy Therapy of Tumor. Z. Wang, S. Liu, L. Wang, H. Zou, Z. Wang, X. Tang, W. Feng, Y. Chong, Y. Liu, B. Yang, H. Zhang, July 2020, ACS Applied Bio Materials, DOI Link
Fabrication of multifunctional polydopamine-coated gold nanobones for PA/CT imaging and enhanced synergistic chemo-photothermal therapy. J. Xu, X. Cheng, F. Chen, W. Li, X. Xiao, P. Lai, G. Xu, L. Xu, Y. Pan, July 2020, Journal of Materials Science and Technology, DOI Link
Mesenchymal Bmp7 Controls Onset of Tooth Mineralization: A Novel Way to Regulate Molar Cusp Shape. Z. Malik, D. Roth, F. Eaton, J. Theodor, D. Graf, July 2020, Frontiers in Physiology, DOI Link
Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles. L. Wu, C. Rodríguez-Rodríguez, D. Cun, M. Yang, K. Saatchi, U. Häfeli, July 2020, European Journal of Pharmaceutics and Biopharmaceutics, PubMed Link, DOI Link
EXIRAD-3D: Fast automated three-dimensional autoradiography. M. Nguyen, R. Ramakers, C. Kamphuis, S. Koustoulidou, M. Goorden, F. Beekman, July 2020, Nuclear Medicine and Biology, PubMed Link, DOI Link
Tumor microenvironment (TME)-activatable circular aptamer-PEG as an effective hierarchical-targeting molecular medicine for photodynamic therapy. Y. Yang, W. Zhu, L. Cheng, R. Cai, X. Yi, J. He, X. Pan, L. Yang, K. Yang, Z. Liu, W. Tan, M. Chen, July 2020, Biomaterials, PubMed Link, DOI Link
Monosized Polymeric Microspheres Designed for Passive Lung Targeting: Biodistribution and Pharmacokinetics after Intravenous Administration. M. Agnoletti, M. Agnoletti, C. Rodríguez-Rodríguez, C. Rodríguez-Rodríguez, S. Kłodzińska, T. Esposito, T. Esposito, K. Saatchi, H. Mørck Nielsen, U. Häfeli, U. Häfeli, June 2020, ACS Nano, PubMed Link, DOI Link
Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice. Y. Sanders, X. Lyv, Q. Jennifer Zhou, Z. Xiang, D. Stanford, S. Bodduluri, S. Rowe, V. Thannickal, June 2020, JCI Insight, PubMed Link, DOI Link
Characterization of a mouse model to study the relationship between apical periodontitis and atherosclerosis. Y. Berlin-Broner, M. Alexiou, L. Levin, M. Febbraio, June 2020, International Endodontic Journal, PubMed Link, DOI Link
Accelerated image reconstruction by a combined dual-matrix dual-voxel approach. M. Goorden, C. Kamphuis, R. Ramakers, F. Beekman, June 2020, Physics in Medicine and Biology, PubMed Link, DOI Link
Effect of peritumoral bupivacaine on primary and distal hyperalgesia in cancer-induced bone pain. S. Mathew, P. Madhusudanan, S. Shankarappa, June 2020, Journal of Pain Research, PubMed Link, DOI Link
Dissolution and Vertical Transport of Uranium from Stable Mineral Forms by Plants as Influenced by the Co-occurrence of Uranium with Phosphorus. N. Edayilam, B. Ferguson, D. Montgomery, A. Al Mamun, N. Martinez, B. Powell, B. Powell, N. Tharayil, June 2020, Environmental Science and Technology, PubMed Link, DOI Link
Radioactive labeling of milk-derived exosomes with99mTC and in vivo tracking by SPECT imaging. M. González, P. Martín-Duque, M. Desco, B. Salinas, May 2020, Nanomaterials, DOI Link
Radiolabeled cCPE peptides for SPECT imaging of claudin-4 overexpression in pancreatic cancer. J. Torres, M. Mosley, S. Koustoulidou, S. Hopkins, S. Knapp, A. Chaikuad, M. Kondoh, K. Tachibana, V. Kersemans, B. Cornelissen, May 2020, Journal of Nuclear Medicine, PubMed Link, DOI Link
Moment arm function dictates patella sagittal height anatomy: Rabbit epiphysiodesis model alters limb length ratios and subsequent patellofemoral anatomical development. M. Dan, W. Parr, J. Crowley, R. Oliver, K. Kai Lun, V. Lovric, M. Cross, D. Broe, W. Walsh, May 2020, Journal of Orthopaedic Research, PubMed Link, DOI Link
Attenuated: Salmonella typhimurium-mediated tumour targeting imaging based on peptides. S. Xiong, Z. Qi, J. Ni, J. Zhong, L. Cao, K. Yang, May 2020, Biomaterials Science, PubMed Link, DOI Link
Airway remodeling in ferrets with cigarette smoke-induced COPD using μCT imaging. D. Stanford, H. Kim, S. Bodduluri, J. la Fontaine, S. Byzek, T. Schoeb, E. Harris, H. Nath, S. Bhatt, S. Vamsee Raju, S. Rowe, May 2020, American Journal of Physiology – Lung Cellular and Molecular Physiology, PubMed Link, DOI Link
Polymeric Nanoparticles with Neglectable Protein Corona. I. Alberg, S. Kramer, M. Schinnerer, Q. Hu, C. Seidl, C. Leps, N. Drude, D. Möckel, C. Rijcken, T. Lammers, M. Diken, M. Maskos, S. Morsbach, K. Landfester, S. Tenzer, M. Barz, R. Zentel, May 2020, Small, PubMed Link, DOI Link
Immuno-imaging of ICAM-1 in tumours by SPECT. M. Mosley, J. Baguña Torres, D. Allen, B. Cornelissen, May 2020, Nuclear Medicine and Biology, PubMed Link, DOI Link
Paradoxical aortic stiffening and subsequent cardiac dysfunction in Hutchinson–Gilford progeria syndrome. S. Murtada, Y. Kawamura, A. Caulk, H. Ahmadzadeh, N. Mikush, K. Zimmerman, D. Kavanagh, D. Weiss, M. Latorre, Z. Zhuang, G. Shadel, D. Braddock, J. Humphrey, May 2020, Journal of the Royal Society Interface, PubMed Link, DOI Link
Imaging DNA damage repair in vivo after 177Lu-DOTATATE therapy. E. O’Neill, V. Kersemans, P. Allen, S. Terry, J. Torres, M. Mosley, S. Smart, B. Lee, N. Falzone, K. Vallis, M. Konijnenberg, M. De Jong, J. Nonnekens, B. Cornelissen, May 2020, Journal of Nuclear Medicine, PubMed Link, DOI Link
Imaging of inflammatory cellular protagonists in human atherosclerosis: a dual-isotope SPECT approach. H. Barrett, E. Meester, K. van Gaalen, K. van der Heiden, B. Krenning, F. Beekman, E. de Blois, J. de Swart, H. Verhagen, T. Maina, B. Nock, J. Norenberg, M. de Jong, F. Gijsen, M. Bernsen, April 2020, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
H 2 CHX hox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [ nat/67/68 Ga]Ga 3+. X. Wang, M. Jaraquemada-Peláez, Y. Cao, A. Ingham, C. Rodríguez-Rodríguez, J. Pan, Y. Wang, K. Saatchi, U. Häfeli, K. Lin, C. Orvig, April 2020, Inorganic Chemistry, PubMed Link, DOI Link
Smooth Muscle Cell Reprogramming in Aortic Aneurysms. P. Chen, L. Qin, G. Li, J. Malagon-Lopez, Z. Wang, S. Bergaya, S. Gujja, A. Caulk, S. Murtada, X. Zhang, Z. Zhuang, D. Rao, G. Wang, Z. Tobiasova, B. Jiang, R. Montgomery, L. Sun, H. Sun, E. Fisher, J. Gulcher, C. Fernandez-Hernando, J. Humphrey, G. Tellides, T. Chittenden, M. Simons, April 2020, Cell Stem Cell, PubMed Link, DOI Link
Radiolabeled human monoclonal antibody 067-213 has the potential for noninvasive quantification of cd73 expression. H. Sudo, A. Tsuji, A. Sugyo, G. Kurosawa, Y. Kurosawa, D. Alexander, H. Tsuda, T. Saga, T. Higashi, March 2020, International Journal of Molecular Sciences, PubMed Link, DOI Link
Quasi-amorphous and Hierarchical Fe2O3 Supraparticles: Active T1-Weighted Magnetic Resonance Imaging in Vivo and Renal Clearance. M. Ma, H. Zhu, J. Ling, S. Gong, Y. Zhang, Y. Xia, Z. Tang, March 2020, ACS nano, PubMed Link, DOI Link
Preclinical Single Photon Emission Computed Tomography of Alpha Particle-Emitting Radium-223. D. Abou, A. Rittenbach, R. Tomlinson, P. Finley, B. Tsui, B. Simons, A. Jha, D. Ulmert, R. Riddle, D. Thorek, March 2020, Cancer Biotherapy and Radiopharmaceuticals, PubMed Link, DOI Link
Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation. J. Owen, E. Thomas, J. Menon, M. Gray, I. Skaripa-Koukelli, M. Gill, S. Wallington, R. Miller, K. Vallis, R. Carlisle, March 2020, Journal of Controlled Release, PubMed Link, DOI Link
Development and feasibility of quantitative dynamic cardiac imaging for mice using μSPECT. M. Guerraty, L. Johnson, E. Blankemeyer, D. Rader, S. Moore, S. Metzler, March 2020, Journal of Nuclear Cardiology, PubMed Link, DOI Link
Effect of modulating FcRn binding on direct and pretargeted tumor uptake of full-length antibodies. L. Nazarova, H. Rafidi, D. Mandikian, G. Ferl, J. Koerber, C. Davies, S. Ulufatu, J. Ho, J. Lau, S. Yu, J. Ernst, J. Sadowsky, C. Boswell, February 2020, Molecular Cancer Therapeutics, PubMed Link, DOI Link
Hybrid tracers based on cyanine backbones targeting prostate-specific membrane antigen: Tuning pharmacokinetic properties and exploring dye-protein interaction [Computer software]. A. Hensbergen, T. Buckle, D. van Willigen, M. Schottelius, M. Welling, F. van der Wijk, T. Maurer, H. van der Poel, G. van der Pluijm, W. van Weerden, H. Wester, F. van Leeuwen, February 2020, Journal of Nuclear Medicine, PubMed Link, DOI Link
Prospective comparison of PET imaging with PSMA-targeted 18F-DCFPyL versus NA18F for bone lesion detection in patients with metastatic prostate cancer. S. Rowe, X. Li, B. Trock, R. Werner, S. Frey, M. DiGianvittorio, J. Keith Bleiler, D. Reyes, R. Abdallah, K. Pienta, M. Gorin, M. Pomper, February 2020, Journal of Nuclear Medicine, PubMed Link, DOI Link
Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging. R. Vandergaast, S. Khongwichit, H. Jiang, T. DeGrado, K. Peng, D. Smith, S. Russell, L. Suksanpaisan, January 2020, Cancer Gene Therapy, PubMed Link, DOI Link
Visualization of AMPA receptors in living human brain with positron emission tomography. T. Miyazaki, W. Nakajima, M. Hatano, Y. Shibata, Y. Kuroki, T. Arisawa, A. Serizawa, A. Sano, S. Kogami, T. Yamanoue, K. Kimura, Y. Hirata, Y. Takada, Y. Ishiwata, M. Sonoda, M. Tokunaga, C. Seki, Y. Nagai, T. Minamimoto, K. Kawamura, M. Zhang, N. Ikegaya, M. Iwasaki, N. Kunii, Y. Kimura, F. Yamashita, M. Taguri, H. Tani, N. Nagai, T. Koizumi, S. Nakajima, M. Mimura, M. Yuzaki, H. Kato, M. Higuchi, H. Uchida, T. Takahashi, January 2020, Nature Medicine, PubMed Link, DOI Link
Radioprotective Garment-Inspired Biodegradable Polymetal Nanoparticles for Enhanced CT Contrast Production. J. Kim, A. Silva, J. Hsu, P. Maidment, N. Shapira, P. Noël, D. Cormode, January 2020, Chemistry of Materials, PubMed Link, DOI Link
Design of iodinated radioligands for SPECT imaging of central human 5-HT4R using a ligand lipophilicity efficiency approach. V. Babin, B. Tournier, A. Davis, E. Dubost, G. Pigrée, J. Lohier, V. Reboul, T. Cailly, J. Bouillon, P. Millet, F. Fabis, January 2020, Bioorganic Chemistry, PubMed Link, DOI Link
Optimized sampling for high resolution multi-pinhole brain SPECT with stationary detectors. Y. Chen, M. Goorden, B. Vastenhouw, F. Beekman, January 2020, Physics in Medicine and Biology, PubMed Link, DOI Link
Induction assisted friction stir welding: a review. D. Mohan, S. Gopi, January 2020, Australian Journal of Mechanical Engineering, DOI Link

2019

A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice. S. Demine, R. Garcia Ribeiro, J. Thevenet, L. Marselli, P. Marchetti, F. Pattou, J. Kerr-Conte, N. Devoogdt, D. Eizirik, December 2019, Diabetologia, PubMed Link, DOI Link
CAIX-targeting radiotracers for hypoxia imaging in head and neck cancer models. F. Huizing, J. Garousi, J. Lok, G. Franssen, B. Hoeben, F. Frejd, O. Boerman, J. Bussink, V. Tolmachev, S. Heskamp, December 2019, Scientific Reports, PubMed Link, DOI Link
Reconstructing granular particles from X-ray computed tomography using the TWS machine learning tool and the level set method. Z. Lai, Q. Chen, November 2019, Acta Geotechnica, DOI Link
A high-sucrose diet aggravates Alzheimer’s disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice. S. Yeh, F. Shie, H. Liu, H. Yao, P. Kao, Y. Lee, L. Chen, S. Hsu, L. Chao, K. Wu, Y. Shiao, H. Tsay, November 2019, Neurobiology of Aging, PubMed Link, DOI Link
Multimodal image-guided surgery of HER2-positive breast cancer using [111In]In-DTPA-trastuzumab-IRDye800CW in an orthotopic breast tumor model. M. Deken, D. Bos, W. Tummers, T. March, C. van de Velde, M. Rijpkema, A. Vahrmeijer, November 2019, EJNMMI Research, PubMed Link, DOI Link
Effect of Gold Nanoparticle Size on Their Properties as Contrast Agents for Computed Tomography. Y. Dong, M. Hajfathalian, P. Maidment, J. Hsu, P. Naha, S. Si-Mohamed, M. Breuilly, J. Kim, P. Chhour, P. Douek, H. Litt, D. Cormode, October 2019, Scientific Reports, PubMed Link, DOI Link
Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors. E. Bolli, M. D’Huyvetter, A. Murgaski, D. Berus, G. Stangé, E. Clappaert, S. Arnouk, A. Pombo Antunes, A. Krasniqi, T. Lahoutte, A. Gonçalves, M. Vuylsteke, G. Raes, N. Devoogdt, K. Movahedi, J. Van Ginderachter, October 2019, Journal of Controlled Release, PubMed Link, DOI Link
Imaging of atherosclerosis, targeting LFA-1 on inflammatory cells with 111In-DANBIRT. E. Meester, B. Krenning, R. de Blois, J. Norenberg, M. de Jong, M. Bernsen, K. Van der Heiden, October 2019, Journal of Nuclear Cardiology, PubMed Link, DOI Link
Plant-derived chlorophyll derivative loaded liposomes for tri-model imaging guided photodynamic therapy. H. Zhou, L. Xia, J. Zhong, S. Xiong, X. Yi, L. Chen, R. Zhu, Q. Shi, K. Yang, October 2019, Nanoscale, PubMed Link, DOI Link
Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection. L. Zhang, L. Suksanpaisan, H. Jiang, T. DeGrado, S. Russell, M. Zhao, K. Peng, October 2019, Molecular Therapy – Oncolytics, DOI Link
Tumor imaging using radiolabeled matrix metalloproteinase-activated anthrax proteins. M. Xavier, S. Liu, T. Bugge, J. Torres, M. Mosley, S. Hopkins, P. Allen, G. Berridge, I. Vendrell, R. Fischer, V. Kersemans, S. Smart, S. Leppla, B. Cornelissen, October 2019, Journal of Nuclear Medicine, PubMed Link, DOI Link
111 In-Labeled Glycoprotein Nonmetastatic b (GPNMB) Targeted Gemini Surfactant-Based Nanoparticles against Melanoma: In Vitro Characterization and in Vivo Evaluation in Melanoma Mouse Xenograft Model. A. Makhlouf, I. Hajdu, S. Hartimath, E. Alizadeh, K. Wharton, K. Wasan, I. Badea, H. Fonge, 2019, Molecular Pharmaceutics, PubMed Link, DOI Link
Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy. Z. Dong, L. Feng, Y. Chao, Y. Hao, M. Chen, F. Gong, X. Han, R. Zhang, L. Cheng, Z. Liu, 2019, Nano Letters, PubMed Link, DOI Link
TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer’s disease. B. Tournier, S. Tsartsalis, D. Rigaud, C. Fossey, T. Cailly, F. Fabis, T. Pham, M. Grégoire, E. Kövari, M. Moulin-Sallanon, A. Savioz, P. Millet, September 2019, Neurobiology of Disease, PubMed Link, DOI Link
Nanoagents Based on Poly(ethylene glycol)-b-Poly(l-thyroxine) Block Copolypeptide for Enhanced Dual-Modality Imaging and Targeted Tumor Radiotherapy. X. Gu, Z. Zhu, Q. Fan, Y. Wei, G. Wang, F. Meng, Z. Zhong, C. Deng, September 2019, Small, PubMed Link, DOI Link
111In- And 225Ac-Labeled Cixutumumab for Imaging and α-Particle Radiotherapy of IGF-1R Positive Triple-Negative Breast Cancer [Computer software]. V. Solomon, E. Alizadeh, W. Bernhard, S. Hartimath, W. Hill, R. Chekol, K. Barreto, C. Geyer, H. Fonge, H. Fonge, September 2019, Molecular Pharmaceutics, PubMed Link, DOI Link
A pretargeted multimodal approach for image-guided resection in a xenograft model of colorectal cancer. F. Elekonawo, S. Lütje, G. Franssen, D. Bos, D. Goldenberg, O. Boerman, M. Rijpkema, September 2019, EJNMMI Research, DOI Link
Imaging of translocator protein upregulation is selective for pro-inflammatory polarized astrocytes and microglia. M. Pannell, V. Economopoulos, T. Wilson, V. Kersemans, P. Isenegger, J. Larkin, S. Smart, S. Gilchrist, V. Gouverneur, N. Sibson, September 2019, Glia, PubMed Link, DOI Link
Epilepsy-related and other causes of mortality in people with epilepsy: A systematic review of systematic reviews. G. Mbizvo, K. Bennett, C. Simpson, S. Duncan, R. Chin, August 2019, Epilepsy Research, PubMed Link, DOI Link
Detection and targeting insulin growth factor receptor type 2 (IGF2R) in osteosarcoma PDX in mouse models and in canine osteosarcoma tumors. S. Karkare, K. Allen, R. Jiao, M. Malo, W. Dawicki, M. Helal, D. Godson, R. Dickinson, V. MacDonald-Dickinson, R. Yang, B. Hoang, R. Gorlick, D. Geller, E. Dadachova, August 2019, Scientific Reports, PubMed Link, DOI Link
Preclinical evaluation of 111In-labeled peGylated maytansine nimotuzumab drug conjugates in EGFR-positive cancer models. S. Hartimath, E. Alizadeh, V. Solomon, R. Chekol, W. Bernhard, W. Hill, A. Parada, K. Barreto, C. Geyer, H. Fonge, August 2019, Journal of Nuclear Medicine, PubMed Link, DOI Link
T1/T2-weighted magnetic resonance imaging and SPECT imaging guided combined radioisotope therapy and chemotherapy using functionalized reduced graphene oxide-manganese ferrite nanocomposites. R. Qian, D. Maiti, J. Zhong, S. Xiong, H. Zhou, R. Zhu, J. Wan, K. Yang, August 2019, Carbon, DOI Link
Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy. E. Thomas, J. Menon, J. Owen, I. Skaripa-Koukelli, S. Wallington, M. Gray, C. Mannaris, V. Kersemans, D. Allen, P. Kinchesh, S. Smart, R. Carlisle, K. Vallis, July 2019, Theranostics, PubMed Link, DOI Link
Measuring the Pancreatic ß Cell Mass in Vivo with Exendin SPECT during Hyperglycemia and Severe Insulitis. L. Joosten, M. Brom, H. Peeters, D. Bos, E. Himpe, L. Bouwens, O. Boerman, M. Gotthardt, July 2019, Molecular Pharmaceutics, PubMed Link, DOI Link
Click Chemistry in the Design and Production of Hybrid Tracers. A. Hensbergen, D. Van Willigen, M. Welling, F. Van Der Wijk, C. De Korne, M. Van Oosterom, M. Schottelius, H. Wester, T. Buckle, F. Van Leeuwen, July 2019, ACS Omega, DOI Link
Activatable Hybrid Polyphosphazene-AuNP Nanoprobe for ROS Detection by Bimodal PA/CT Imaging. M. Bouché, M. Pühringer, A. Iturmendi, A. Amirshaghaghi, A. Tsourkas, I. Teasdale, D. Cormode, July 2019, ACS Applied Materials and Interfaces, PubMed Link, DOI Link
Comparative radioimmunotherapy of experimental melanoma with novel humanized antibody to melanin labeled with 213bismuth and 177lutetium. K. Allen, R. Jiao, M. Malo, C. Frank, D. Fisher, D. Rickles, E. Dadachova, July 2019, Pharmaceutics, DOI Link
Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer. R. Jiao, K. Allen, M. Malo, M. Helal, Z. Jiang, K. Smart, S. Buhl, D. Rickles, R. Bryan, E. Dadachova, July 2019, Cancer Medicine, PubMed Link, DOI Link
Noninvasive in vivo quantification of adeno-associated virus serotype 9–mediated expression of the sodium/iodide symporter under hindlimb ischemia and neuraminidase desialylation in skeletal muscle using single-photon emission computed tomography/computed. N. Boutagy, S. Ravera, X. Papademetris, J. Onofrey, Z. Zhuang, J. Wu, A. Feher, M. Stacy, B. French, B. Annex, N. Carrasco, A. Sinusas, July 2019, Circulation: Cardiovascular Imaging, PubMed Link, DOI Link
Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A. O. Cil, M. Anderson, R. Yen, B. Kelleher, T. Huynh, Y. Seo, S. Nilsen, J. Turner, A. Verkman, July 2019, FASEB Journal, PubMed Link, DOI Link
Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease. S. Kim, S. Kwon, T. Kam, N. Panicker, S. Karuppagounder, S. Lee, J. Lee, W. Kim, M. Kook, C. Foss, C. Shen, H. Lee, S. Kulkarni, P. Pasricha, G. Lee, M. Pomper, V. Dawson, T. Dawson, H. Ko, June 2019, Neuron, PubMed Link, DOI Link
Fluorescence-activated cell sorting to reveal the cell origin of radioligand binding. B. Tournier, S. Tsartsalis, K. Ceyzériat, Z. Medina, B. Fraser, M. Grégoire, E. Kövari, P. Millet, June 2019, Journal of Cerebral Blood Flow and Metabolism, PubMed Link, DOI Link
Evaluating a single domain antibody targeting human PD-L1 as a nuclear imaging and therapeutic agent. K. Broos, Q. Lecocq, C. Xavier, J. Bridoux, T. Nguyen, J. Corthals, S. Schoonooghe, E. Lion, G. Raes, M. Keyaerts, N. Devoogdt, K. Breckpot, June 2019, Cancers, DOI Link
A carbon-fiber sheet resistor for mr-, ct-, spect-, and pet-compatible temperature maintenance in small animals. V. Kersemans, S. Gilchrist, S. Wallington, P. Allen, A. Gomes, G. Dias, B. Cornelissen, P. Kinchesh, S. Smart, June 2019, Tomography, PubMed Link, DOI Link
Two-dimensional metal-organic-framework as a unique theranostic nano-platform for nuclear imaging and chemo-photodynamic cancer therapy. W. Zhu, Y. Yang, Q. Jin, Y. Chao, L. Tian, J. Liu, Z. Dong, Z. Liu, May 2019, Nano Research, DOI Link
Chlorambucil targets BRCA 1/2‐deficient tumours and counteracts PARP inhibitor resistance. E. Tacconi, S. Badie, G. De Gregoriis, T. Reisländer, X. Lai, M. Porru, C. Folio, J. Moore, A. Kopp, J. Baguña Torres, D. Sneddon, M. Green, S. Dedic, J. Lee, A. Batra, O. Rueda, A. Bruna, C. Leonetti, C. Caldas, B. Cornelissen, L. Brino, A. Ryan, A. Biroccio, M. Tarsounas, May 2019, EMBO Molecular Medicine, PubMed Link, DOI Link
Evaluation of pinhole collimator materials for micron-resolution ex vivo SPECT. M. Nguyen, M. Goorden, C. Kamphuis, F. Beekman, May 2019, Physics in Medicine and Biology, PubMed Link, DOI Link
Characterization of BAT activity in rats using invasive and non-invasive techniques. A. Paulus, P. van Ewijk, E. Nascimento, M. De Saint-Hubert, G. Hendrikx, A. Vogg, I. Pooters, M. Schnijderberg, J. Vanderlocht, G. Bos, B. Brans, V. Schrauwen-Hinderling, F. Mottaghy, M. Bauwens, May 2019, PLoS ONE, PubMed Link, DOI Link
Monitoring 111In-labelled polyisocyanopeptide (PIC) hydrogel wound dressings in full-thickness wounds. R. Op ‘T Veld, L. Joosten, O. Van Den Boomen, O. Boerman, P. Kouwer, E. Middelkoop, A. Rowan, J. Jansen, X. Walboomers, F. Wagener, May 2019, Biomaterials Science, PubMed Link, DOI Link
Iodine-Rich Polymersomes Enable Versatile SPECT/CT Imaging and Potent Radioisotope Therapy for Tumor in Vivo. J. Cao, Y. Wei, Y. Zhang, G. Wang, X. Ji, Z. Zhong, May 2019, ACS Applied Materials and Interfaces, PubMed Link, DOI Link
Development and characterization of a theranostic multimodal anti-PSMA targeting agent for imaging, surgical guidance, and targeted photodynamic therapy of PSMA-expressing tumors. S. Lütje, S. Heskamp, G. Franssen, C. Frielink, A. Kip, M. Hekman, G. Fracasso, M. Colombatti, K. Herrmann, O. Boerman, M. Gotthardt, M. Rijpkema, May 2019, Theranostics, PubMed Link, DOI Link
Daratumumab-225Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors. W. Dawicki, K. Allen, R. Jiao, M. Malo, M. Helal, M. Berger, D. Ludwig, E. Dadachova, May 2019, OncoImmunology, PubMed Link, DOI Link
Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice. M. Welling, C. De Korne, S. Spa, D. Van Willigen, A. Hensbergen, A. Bunschoten, N. Duszenko, W. Smits, M. Roestenberg, F. Van Leeuwen, April 2019, ACS Infectious Diseases, PubMed Link, DOI Link
Rational Design and Synthesis of a Metalloproteinase-Activatable Probe for Dual-Modality Imaging of Metastatic Lymph Nodes in Vivo. L. Yin, H. Sun, M. Zhao, A. Wang, S. Qiu, Y. Gao, J. DIng, S. Ji, H. Shi, M. Gao, April 2019, Journal of Organic Chemistry, PubMed Link, DOI Link
Restoration of brain circulation and cellular functions hours post-mortem. Z. Vrselja, S. Daniele, J. Silbereis, F. Talpo, Y. Morozov, A. Sousa, B. Tanaka, M. Skarica, M. Pletikos, N. Kaur, Z. Zhuang, Z. Liu, R. Alkawadri, A. Sinusas, S. Latham, S. Waxman, N. Sestan, April 2019, Nature, PubMed Link, DOI Link
Angiotensin Receptor Neprilysin Inhibitor Attenuates Myocardial Remodeling and Improves Infarct Perfusion in Experimental Heart Failure. D. Pfau, S. Thorn, J. Zhang, N. Mikush, J. Renaud, R. Klein, R. deKemp, X. Wu, X. Hu, A. Sinusas, L. Young, D. Tirziu, April 2019, Scientific Reports, PubMed Link, DOI Link
cRGD-decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo. X. Gu, Y. Wei, Q. Fan, H. Sun, R. Cheng, Z. Zhong, C. Deng, March 2019, Journal of Controlled Release, PubMed Link, DOI Link
Quantification of myocardial uptake rate constants in dynamic small-animal SPECT using a cardiac phantom. L. Johnson, M. Guerraty, S. Moore, S. Metzler, March 2019, Physics in Medicine and Biology, PubMed Link, DOI Link
Data Curation for Preclinical and Clinical Multimodal Imaging Studies. G. Yamoah, L. Cao, C. Wu, F. Beekman, B. Vandeghinste, J. Mannheim, S. Rosenhain, K. Leonardic, F. Kiessling, F. Gremse, March 2019, Molecular Imaging and Biology, PubMed Link, DOI Link
Dual-isotope imaging allows in vivo immunohistochemistry using radiolabelled antibodies in tumours. J. Knight, M. Mosley, V. Kersemans, G. Dias, P. Allen, S. Smart, B. Cornelissen, February 2019, Nuclear Medicine and Biology, PubMed Link, DOI Link
Boosting the Radiosensitizing and Photothermal Performance of Cu2-xSe Nanocrystals for Synergetic Radiophotothermal Therapy of Orthotopic Breast Cancer. Q. Huang, S. Zhang, H. Zhang, Y. Han, H. Liu, F. Ren, Q. Sun, Z. Li, M. Gao, February 2019, ACS Nano, PubMed Link, DOI Link
Lymphodepletion with CD45 Radioimmunotherapy as a Targeted Conditioning Regimen Prior to Adoptive Cell Therapy or CAR-T. D. Ludwig, W. Dawicki, K. Allen, R. Garg, E. Geoghegan, E. Dadachova, M. Berger, January 2019, Biology of Blood and Marrow Transplantation, DOI Link
Quantitatively Visualizing Tumor-Related Protease Activity in Vivo Using a Ratiometric Photoacoustic Probe. L. Yin, H. Sun, H. Zhang, L. He, L. Qiu, J. Lin, H. Xia, Y. Zhang, S. Ji, H. Shi, M. Gao, January 2019, Journal of the American Chemical Society, PubMed Link, DOI Link
Radioembolization of hepatocellular carcinoma with built-in dosimetry: First in vivo results with uniformly-sized, biodegradable microspheres labeled with 188Re. J. De La Vega, P. Esquinas, C. Rodríguez-Rodríguez, M. Bokharaei, I. Moskalev, D. Liu, K. Saatchi, U. Häfeli, January 2019, Theranostics, PubMed Link, DOI Link
Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages. C. Xavier, A. Blykers, D. Laoui, E. Bolli, I. Vaneyken, J. Bridoux, H. Baudhuin, G. Raes, H. Everaert, K. Movahedi, J. Van Ginderachter, N. Devoogdt, V. Caveliers, T. Lahoutte, M. Keyaerts, January 2019, Molecular Imaging and Biology, PubMed Link, DOI Link
In Vivo Photoacoustic/Single-Photon Emission Computed Tomography Imaging for Dynamic Monitoring of Aggregation-Enhanced Photothermal Nanoagents. Y. Wang, Y. Wang, Z. Sun, Z. Chen, Y. Wu, Y. Gu, S. Lin, January 2019, Analytical Chemistry, PubMed Link, DOI Link
PD-L1 microSPECT/CT imaging for longitudinal monitoring of PD-L1 expression in syngeneic and humanized mouse models for cancer. S. Heskamp, P. Wierstra, J. Molkenboer-Kuenen, G. Sandker, S. Thordardottir, J. Cany, D. Olive, J. Bussink, O. Boerman, H. Dolstra, E. Aarntzen, W. Hobo, January 2019, Cancer Immunology Research, PubMed Link, DOI Link

2018

Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies. E. Hood, C. Greineder, T. Shuvaeva, L. Walsh, C. Villa, V. Muzykantov, 2018, Bioconjugate Chemistry, PubMed Link, DOI Link
New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging. B. Brunton, L. Suksanpaisan, H. Li, Q. Liu, Y. Yu, A. Vrieze, L. Zhang, N. Jenks, H. Jiang, T. DeGrado, C. Zhao, S. Russell, K. Peng, December 2018, Scientific Reports, PubMed Link, DOI Link
Sulfonyl-Containing Boronate Caps for Optimization of Biological Properties of 99m Tc(III) Radiotracers [ 99m TcCl(CDO)(CDOH) 2 B-R] (CDOH 2 = Cyclohexanedione Dioxime). Z. Zhao, M. Liu, W. Fang, S. Liu, 2018, Journal of Medicinal Chemistry, PubMed Link, DOI Link
Quantitative Imaging of the Hypoxia-Related Marker CAIX in Head and Neck Squamous Cell Carcinoma Xenograft Models. F. Huizing, B. Hoeben, G. Franssen, O. Boerman, S. Heskamp, J. Bussink, December 2018, Molecular Pharmaceutics, PubMed Link, DOI Link
Cu-Fe-Se Ternary Nanosheet-Based Drug Delivery Carrier for Multimodal Imaging and Combined Chemo/Photothermal Therapy of Cancer. X. Jiang, Y. Han, H. Zhang, H. Liu, Q. Huang, T. Wang, Q. Sun, Z. Li, December 2018, ACS Applied Materials and Interfaces, PubMed Link, DOI Link
A 89 Zr-labeled lipoplex nanosystem for image-guided gene delivery: Design, evaluation of stability and in vivo behavior. I. Hajdu, A. Makhlouf, V. Solomon, D. Michel, M. Al-Dulaymi, K. Wasan, H. Fonge, I. Badea, 2018, International Journal of Nanomedicine, PubMed Link, DOI Link
Dual-isotope SPECT/CT imaging of the tuberculosis subunit vaccine H56/CAF01: Induction of strong systemic and mucosal IgA and T-cell responses in mice upon subcutaneous prime and intrapulmonary boost immunization. A. Thakur, C. Rodríguez-Rodríguez, K. Saatchi, F. Rose, T. Esposito, Z. Nosrati, P. Andersen, D. Christensen, U. Häfeli, C. Foged, November 2018, Frontiers in Immunology, PubMed Link, DOI Link
In vivo stability of supramolecular host–guest complexes monitored by dual-isotope multiplexing in a pre-targeting model of experimental liver radioembolization. M. Welling, S. Spa, D. van Willigen, D. Rietbergen, M. Roestenberg, T. Buckle, F. van Leeuwen, November 2018, Journal of Controlled Release, PubMed Link, DOI Link
Antitumor activity of auger electron emitter 111In delivered by modular nanotransporter for treatment of bladder cancer with EGFR overexpression. A. Rosenkranz, T. Slastnikova, T. Karmakova, M. Vorontsova, N. Morozova, V. Petriev, A. Abrosimov, Y. Khramtsov, T. Lupanova, A. Ulasov, R. Yakubovskaya, G. Georgiev, A. Sobolev, November 2018, Frontiers in Pharmacology, PubMed Link, DOI Link
Whole-body imaging of cell death provides a systemic, minimally invasive, dynamic, and near-real time indicator for chemotherapeutic drug toxicity. S. Johnson, A. Ugolkov, C. Haney, G. Bondarenko, L. Li, E. Waters, R. Bergan, A. Tran, T. O’Halloran, A. Mazar, M. Zhao, November 2018, Clinical Cancer Research, PubMed Link, DOI Link
99mTc(CO)3+ labeled domain I/II-specific anti-EGFR (scFv)2 antibody fragment for imaging EGFR expression. V. Solomon, C. Gonzalez, E. Alizadeh, W. Bernhard, S. Hartimath, K. Barreto, C. Geyer, H. Fonge, 2018, European Journal of Medicinal Chemistry, PubMed Link, DOI Link
H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry. X. Wang, M. Jaraquemada-Peláez, C. Rodríguez-Rodríguez, Y. Cao, C. Buchwalder, N. Choudhary, U. Jermilova, C. Ramogida, K. Saatchi, U. Häfeli, B. Patrick, C. Orvig, November 2018, Journal of the American Chemical Society, PubMed Link, DOI Link
Imaging of Folate Receptor Expressing Macrophages in the Rat Groove Model of Osteoarthritis: Using a New DOTA-Folate Conjugate. H. de Visser, N. Korthagen, C. Müller, R. Ramakers, G. Krijger, F. Lafeber, F. Beekman, S. Mastbergen, H. Weinans, November 2018, Cartilage, PubMed Link, DOI Link
Optimized image acquisition for dopamine transporter imaging with ultra-high resolution clinical pinhole SPECT. Y. Chen, B. Vastenhouw, C. Wu, M. Goorden, F. Beekman, 2018, Physics in Medicine and Biology, PubMed Link, DOI Link
PET imaging of PARP expression using 18F-olaparib. T. Wilson, M. Xavier, J. Knight, S. Verhoog, J. Torres, M. Mosley, S. Hopkins, S. Wallington, P. Allen, V. Kersemans, R. Hueting, S. Smart, V. Gouverneur, B. Cornelissen, November 2018, Journal of Nuclear Medicine, PubMed Link, DOI Link
Effects of adding an albumin binder chain on [177Lu]Lu-DOTATATE. E. Rousseau, J. Lau, Z. Zhang, C. Uribe, H. Kuo, C. Zhang, J. Zeisler, N. Colpo, K. Lin, F. Bénard, November 2018, Nuclear Medicine and Biology, PubMed Link, DOI Link
Calcium Bisphosphonate Nanoparticles with Chelator-Free Radiolabeling to Deplete Tumor-Associated Macrophages for Enhanced Cancer Radioisotope Therapy. L. Tian, X. Yi, Z. Dong, J. Xu, C. Liang, Y. Chao, Y. Wang, K. Yang, Z. Liu, 2018, ACS Nano, PubMed Link, DOI Link
Ultrasmall Hyperbranched Semiconducting Polymer Nanoparticles with Different Radioisotopes Labeling for Cancer Theranostics. X. Yi, M. Xu, H. Zhou, S. Xiong, R. Qian, Z. Chai, L. Zhao, K. Yang, September 2018, ACS Nano, PubMed Link, DOI Link
Enhancing Treatment Efficacy of 177Lu-PSMA-617 with the Conjugation of an Albumin-Binding Motif: Preclinical Dosimetry and Endoradiotherapy Studies. H. Kuo, H. Merkens, Z. Zhang, C. Uribe, J. Lau, C. Zhang, N. Colpo, K. Lin, F. Bénard, September 2018, Molecular Pharmaceutics, PubMed Link, DOI Link
Oral administration of highly bright Cr3+ doped ZnGa2O4 nanocrystals for in vivo targeted imaging of orthotopic breast cancer. H. Liu, F. Ren, H. Zhang, Y. Han, H. Qin, J. Zeng, Y. Wang, Q. Sun, Z. Li, M. Gao, 2018, Journal of Materials Chemistry B, PubMed Link, DOI Link
Photosensitizer-crosslinked in-situ polymerization on catalase for tumor hypoxia modulation & enhanced photodynamic therapy. H. Wang, Y. Chao, J. Liu, W. Zhu, G. Wang, L. Xu, Z. Liu, 2018, Biomaterials, PubMed Link, DOI Link
Noninvasive Multimodal Imaging of Osteosarcoma and Lymph Nodes Using a 99mTc-Labeled Biomineralization Nanoprobe. Z. Xu, Y. Wang, J. Han, Q. Xu, J. Ren, J. Xu, Y. Wang, Z. Chai, 2018, Analytical Chemistry, PubMed Link, DOI Link
An acidic pH/reduction dual-stimuli responsive nanoprobe for enhanced CT imaging of tumours: In vivo. A. Wang, L. Yin, L. He, H. Xia, F. Chen, M. Zhao, J. Ding, H. Shi, 2018, Nanoscale, PubMed Link, DOI Link
Ultra-small nanocluster mediated synthesis of Nd3+-doped core-shell nanocrystals with emission in the second near-infrared window for multimodal imaging of tumor vasculature. F. Ren, L. Ding, H. Liu, Q. Huang, H. Zhang, L. Zhang, J. Zeng, Q. Sun, Z. Li, M. Gao, 2018, Biomaterials, PubMed Link, DOI Link
Detection of lymph node metastasis with near-infrared upconversion luminescent nanoprobes. S. Qiu, J. Zeng, Y. Hou, L. Chen, J. Ge, L. Wen, C. Liu, Y. Zhang, R. Zhu, M. Gao, 2018, Nanoscale, PubMed Link, DOI Link
Highly effective radioisotope cancer therapy with a non-therapeutic isotope delivered and sensitized by nanoscale coordination polymers. Y. Chao, C. Liang, Y. Yang, G. Wang, D. Maiti, L. Tian, F. Wang, W. Pan, S. Wu, K. Yang, Z. Liu, 2018, ACS Nano, PubMed Link, DOI Link
Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles – A potential theranostic agent for pulmonary metastatic disease. N. Sobol, L. Sutherlin, E. Cedrowska, J. Schorp, C. Rodríguez-Rodríguez, V. Sossi, J. Lattimer, D. Miller, P. Pevsner, J. Robertson, 2018, APL Bioengineering, DOI Link
Biodegradable Nanoagents with Short Biological Half-Life for SPECT/PAI/MRI Multimodality Imaging and PTT Therapy of Tumors. L. Chen, J. Chen, S. Qiu, L. Wen, Y. Wu, Y. Hou, Y. Wang, J. Zeng, Y. Feng, Z. Li, H. Shan, M. Gao, 2018, Small, PubMed Link, DOI Link
Dual-radiotracer translational SPECT neuroimaging. Comparison of three methods for the simultaneous brain imaging of D2/3 and 5-HT2A receptors. S. Tsartsalis, B. Tournier, S. Habiby, M. Ben Hamadi, C. Barca, N. Ginovart, P. Millet, 2018, NeuroImage, PubMed Link, DOI Link
Dual SPECT imaging of 111In and 67Ga to simultaneously determine in vivo the pharmacokinetics of different radiopharmaceuticals: A quantitative tool in pre-clinical research. P. Esquinas, C. Rodríguez-Rodríguez, T. Esposito, J. Harboe, M. Bergamo, A. Celler, K. Saatchi, V. Sossi, U. Häfeli, 2018, Physics in Medicine and Biology, PubMed Link, DOI Link
Prognostic Value of Early Evaluation of Left Ventricular Dyssynchrony After Myocardial Infarction. H. Wakabayashi, J. Taki, A. Inaki, T. Hiromasa, T. Yamase, N. Akatani, K. Okuda, T. Shibutani, K. Shiba, S. Kinuya, September 2018, Molecular Imaging and Biology, PubMed Link, DOI Link
Quantitative SPECT imaging and biodistribution point to molecular weight independent tumor uptake for some long-circulating polymer nanocarriers. V. Schmitt, C. Rodríguez-Rodríguez, J. Hamilton, R. Shenoi, P. Schaffer, V. Sossi, J. Kizhakkedathu, K. Saatchi, U. Häfeli, 2018, RSC Advances, DOI Link
Comparison of the accuracy of FMT/CT and PET/MRI for the assessment of antibody biodistribution in squamous cell carcinoma xenografts. C. Hage, F. Gremse, C. Griessinger, A. Maurer, S. Hoffmann, F. Osl, B. Pichler, F. Kiessling, W. Scheuer, T. Pöschinger, August 2018, Journal of Nuclear Medicine, PubMed Link, DOI Link
Blood circulation, biodistribution, and pharmacokinetics of dextran-modified black phosphorus nanoparticles. C. Sun, Y. Xu, L. Deng, H. Zhang, Q. Sun, C. Zhao, Z. Li, 2018, ACS Applied Bio Materials, DOI Link
Monitoring the Opening and Recovery of the Blood-Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultrasmall Cu2- xSe Nanoparticles. H. Zhang, T. Wang, W. Qiu, Y. Han, Q. Sun, J. Zeng, F. Yan, H. Zheng, Z. Li, M. Gao, August 2018, Nano Letters, PubMed Link, DOI Link
Characterization of 111In-labeled Glucose-Dependent Insulinotropic Polypeptide as a Radiotracer for Neuroendocrine Tumors. S. Willekens, L. Joosten, O. Boerman, M. Brom, M. Gotthardt, 2018, Scientific Reports, PubMed Link, DOI Link
Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using 99m Tc-duramycin during TNF-induced SIRS. T. Delvaeye, L. Wyffels, S. Deleye, K. Lemeire, A. Goncxalves, E. Decrock, S. Staelens, L. Leybaert, P. Vandenabeele, D. Krysko, 2018, Journal of Nuclear Medicine, PubMed Link, DOI Link
18F-Trifluoromethylation of Unmodified Peptides with 5-18F-(Trifluoromethyl)dibenzothiophenium Trifluoromethanesulfonate. S. Verhoog, C. Kee, Y. Wang, T. Khotavivattana, T. Wilson, V. Kersemans, S. Smart, M. Tredwell, B. Davis, V. Gouverneur, 2018, Journal of the American Chemical Society, PubMed Link, DOI Link
Characterization of site-specifically conjugated monomethyl auristatin E-and duocarmycin-based anti-PSMA antibody-drug conjugates for treatment of PSMA-expressing tumors. S. Lutje, D. Gerrits, J. Molkenboer-Kuenen, K. Herrmann, G. Fracasso, M. Colombatti, O. Boerman, S. Heskamp, 2018, Journal of Nuclear Medicine, PubMed Link, DOI Link
Enhanced Specific Activity by Multichelation of Exendin-3 Leads to Improved Image Quality and in Vivo Beta Cell Imaging. L. Joosten, M. Brom, H. Peeters, S. Heskamp, M. Béhé, O. Boerman, M. Gotthardt, 2018, Molecular Pharmaceutics, PubMed Link, DOI Link
Injectable tissue integrating networks from recombinant polypeptides with tunable order. S. Roberts, T. Harmon, J. Schaal, V. Miao, K. Li, A. Hunt, Y. Wen, T. Oas, J. Collier, R. Pappu, A. Chilkoti, 2018, Nature Materials, PubMed Link, DOI Link
Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles, and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics. Z. Liu, Y. Li, W. Li, C. Xiao, D. Liu, C. Dong, M. Zhang, E. Mäkilä, M. Kemell, J. Salonen, J. Hirvonen, H. Zhang, D. Zhou, X. Deng, H. Santos, June 2018, Advanced Materials, PubMed Link, DOI Link
Cancer radiotheranostics targeting carbonic anhydrase-IX with 111 In- and 90 Y-labeled ureidosulfonamide scaffold for SPECT imaging and radionuclide-based therapy. S. Iikuni, M. Ono, H. Watanabe, Y. Shimizu, K. Sano, H. Saji, April 2018, Theranostics, PubMed Link, DOI Link
In vivo estimation of oncolytic virus populations within tumors. M. Jung, C. Offord, M. Ennis, I. Kemler, C. Neuhauser, D. Dingli, 2018, Cancer Research, PubMed Link, DOI Link
Quantification of Myocardial Perfusion Defect Size in Rats: Comparison between Quantitative Perfusion SPECT and Autoradiography. H. Wakabayashi, J. Taki, A. Inaki, T. Hiromasa, K. Okuda, T. Shibutani, K. Shiba, S. Kinuya, 2018, Molecular Imaging and Biology, PubMed Link, DOI Link
Validation of 111 In-exendin SPECT for the determination of the B-cell mass in biobreeding diabetes-prone rats. M. Brom, L. Joosten, C. Frielink, H. Peeters, D. Bos, M. Van Zanten, O. Boerman, M. Gotthardt, 2018, Diabetes, PubMed Link, DOI Link
Tracers for fluorescence-guided surgery: How elongation of the polymethine chain in cyanine dyes alters the pharmacokinetics of a dual-modality c[RGDyK] tracer. T. Buckle, D. Van Willigen, S. Spa, A. Hensbergen, S. Van Der Wal, C. De Korne, M. Welling, H. Van Der Poel, J. Hardwick, F. Van Leeuwen, 2018, Journal of Nuclear Medicine, PubMed Link, DOI Link
Investigation of Newly Prepared Biodegradable 32 P-chromic Phosphate-polylactide-co-glycolide Seeds and Their Therapeutic Response Evaluation for Glioma Brachytherapy. G. Shao, Y. Wang, X. Liu, M. Zhao, J. Song, P. Huang, F. Wang, Z. Wang, 2018, Contrast Media and Molecular Imaging, PubMed Link, DOI Link
Imaging fibroblast activation protein to monitor therapeutic effects of neutralizing interleukin-22 in collagen-induced arthritis. T. van der Geest, D. Roeleveld, B. Walgreen, M. Helsen, T. Nayak, C. Klein, M. Hegen, G. Storm, J. Metselaar, W. van den Berg, P. van der Kraan, P. Laverman, O. Boerman, M. Koenders, 2018, Rheumatology (United Kingdom), PubMed Link, DOI Link
Novel light-guide-PMT geometries to reduce dead edges of a scintillation camera. B. Wang, R. Kreuger, F. Beekman, M. Goorden, April 2018, Physica Medica, PubMed Link, DOI Link
In vivo Biodistribution of Radiolabeled Acoustic Protein Nanostructures. J. Le Floc’h, A. Zlitni, H. Bilton, M. Yin, A. Farhadi, N. Janzen, M. Shapiro, J. Valliant, F. Foster, 2018, Molecular Imaging and Biology, PubMed Link, DOI Link
89Zr-nimotuzumab for immunoPET imaging of epidermal growth factor receptor I. R. Chekol, V. Solomon, E. Alizadeh, W. Bernhard, D. Fisher, W. Hill, K. Barreto, J. DeCoteau, A. Parada, C. Geyer, H. Fonge, March 2018, Oncotarget, PubMed Link, DOI Link
Evaluation of 209At as a theranostic isotope for 209At-radiopharmaceutical development using high-energy SPECT. J. Crawford, A. Robertson, H. Yang, C. Rodríguez-Rodríguez, P. Esquinas, P. Kunz, S. Blinder, V. Sossi, P. Schaffer, T. Ruth, 2018, Physics in Medicine and Biology, PubMed Link, DOI Link
System geometry optimization for molecular breast tomosynthesis with focusing multi-pinhole collimators. J. Van Roosmalen, F. Beekman, M. Goorden, 2018, Physics in Medicine and Biology, PubMed Link, DOI Link
[99mTc]duramycin for cell death imaging: Impact of kit formulation, purification and species difference. L. Palmieri, F. Elvas, C. Vangestel, K. Pak, B. Gray, S. Stroobants, S. Staelens, L. wyffels, January 2018, Nuclear Medicine and Biology, PubMed Link, DOI Link
First Whole-Body Three-Dimensional Tomographic Imaging of Alpha Particle Emitting Radium-223. D. Abou, A. Rittenbach, R. Tomlinson, P. Finley, B. Tsui, B. Simons, D. Ulmert, R. Riddle, D. Thorek, January 2018, bioRxiv, DOI Link

2017

A single-scan protocol for absolute D2/3 receptor quantification with [123I]IBZM SPECT. S. Tsartsalis, B. Tournier, K. Aoun, S. Habiby, D. Pandolfo, A. Dimiziani, N. Ginovart, P. Millet, December 2017, NeuroImage, PubMed Link, DOI Link
188Re image performance assessment using small animal multi-pinhole SPECT/PET/CT system. P. Esquinas, C. Rodríguez-Rodríguez, J. Carlos De La Vega, M. Bokharaei, K. Saatchi, M. Shirmohammad, U. Häfeli, V. Sossi, A. Celler, December 2017, Physica Medica, PubMed Link, DOI Link
Quantitative and longitudinal imaging of intramuscular transplanted islets of Langerhans with SPECT using [123I]IBZM. S. Willekens, I. van der Kroon, D. Bos, L. Joosten, C. Frielink, O. Boerman, M. Brom, M. Gotthardt, December 2017, Diabetes, Obesity and Metabolism, PubMed Link, DOI Link
Radioiodination of BODIPY and its application to a nuclear and optical dual functional labeling agent for proteins and peptides. M. Ono, H. Watanabe, Y. Ikehata, N. Ding, M. Yoshimura, K. Sano, H. Saji, 2017, Scientific Reports, PubMed Link, DOI Link
Preclinical evaluation of PAC1 targeting with radiolabeled Maxadilan. L. Joosten, M. Brom, M. Schäfer, O. Boerman, E. Weihe, M. Gotthardt, December 2017, Scientific Reports, PubMed Link, DOI Link
99mTc-duramycin SPECT imaging of early tumor response to targeted therapy: A comparison with 18F-FDG PET. F. Elvas, J. Boddaert, C. Vangestel, K. Pak, B. Gray, S. Kumar-Singh, S. Staelens, S. Stroobants, L. Wyffels, November 2017, Journal of Nuclear Medicine, PubMed Link, DOI Link
99mTc-3Cboroxime: A novel 99mTc(III) complex [99mTcCl(CDO)(CDOH)2B-3C] (CDOH2 = cyclohexanedione dioxime; 3C-B(OH)2 = 3-(carbamoylphenyl)boronic acid) with high heart uptake and long myocardial retention. M. Liu, S. Liu, October 2017, Dalton Transactions, PubMed Link, DOI Link
Radiolabelled polymeric IgA: From biodistribution to a new molecular imaging tool in colorectal cancer lung metastases. H. Carpenet, A. Cuvillier, A. Perraud, O. Martin, G. Champier, M. Jauberteau, J. Monteil, I. Quelven, October 2017, Oncotarget, PubMed Link, DOI Link
Ultrasmall Magnetic CuFeSe2 Ternary Nanocrystals for Multimodal Imaging Guided Photothermal Therapy of Cancer. X. Jiang, S. Zhang, F. Ren, L. Chen, J. Zeng, M. Zhu, Z. Cheng, M. Gao, Z. Li, 2017, ACS Nano, PubMed Link, DOI Link
Monodisperse Dual Plasmonic [email protected] (E= S, Se) [email protected] Supraparticles: Aqueous Fabrication, Multimodal Imaging, and Tumor Therapy at in Vivo Level. H. Zhu, Y. Wang, C. Chen, M. Ma, J. Zeng, S. Li, Y. Xia, M. Gao, 2017, ACS Nano, PubMed Link, DOI Link
Tumor Microenvironment-Triggered Aggregation of Antiphagocytosis 99mTc-Labeled Fe3O4 Nanoprobes for Enhanced Tumor Imaging In Vivo. Z. Gao, Y. Hou, J. Zeng, L. Chen, C. Liu, W. Yang, M. Gao, 2017, Advanced Materials, PubMed Link, DOI Link
Liposomal treatment of experimental arthritis can be monitored noninvasively with a radiolabeled anti-fibroblast activation protein antibody. T. Van Der Geest, P. Laverman, D. Gerrits, B. Walgreen, M. Helsen, C. Klein, T. Nayak, G. Storm, J. Metselaar, M. Koenders, O. Boerman, August 2017, Journal of Nuclear Medicine, PubMed Link, DOI Link
64Cu-ATSM internal radiotherapy to treat tumors with bevacizumab-induced vascular decrease and hypoxia in human colon carcinoma xenografts. Y. Yoshii, M. Yoshimoto, H. Matsumoto, T. Furukawa, M. Zhang, M. Inubushi, A. Tsuji, Y. Fujibayashi, T. Higashi, T. Saga, 2017, Oncotarget, DOI Link
Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction. H. Saiki, G. Moulay, A. Guenzel, W. Liu, T. Decklever, K. Classic, L. Pham, H. Chen, J. Burnett, S. Russell, M. Redfield, August 2017, American Journal of Physiology – Heart and Circulatory Physiology, PubMed Link, DOI Link
P-NO2-Bn-H4neunpa and H4neunpa-Trastuzumab: Bifunctional Chelator for Radiometalpharmaceuticals and 111In Immuno-Single Photon Emission Computed Tomography Imaging. S. Spreckelmeyer, C. Ramogida, J. Rousseau, K. Arane, I. Bratanovic, N. Colpo, U. Jermilova, G. Dias, I. Dude, M. Jaraquemada-Peláez, F. Bénard, P. Schaffer, C. Orvig, 2017, Bioconjugate Chemistry, PubMed Link, DOI Link
Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma. T. Miran, A. Vogg, L. El Moussaoui, H. Kaiser, N. Drude, V. von Felbert, F. Mottaghy, A. Morgenroth, July 2017, Cancer Medicine, PubMed Link, DOI Link
Hybrid imaging labels: Providing the link between mass spectrometry-based molecular pathology and theranostics. T. Buckle, S. Der Wal, S. Van Malderen, L. Müller, J. Kuil, V. Unen, R. Peters, M. Van Bemmel, L. McDonnell, A. Velders, F. Koning, F. Vanhaeke, F. Van Leeuwen, 2017, Theranostics, PubMed Link, DOI Link
Iminodiacetic acid as bifunctional linker for dimerization of cyclic RGD peptides. D. Xu, Z. Zhao, S. Chen, Y. Yang, W. Fang, S. Liu, May 2017, Nuclear Medicine and Biology, PubMed Link, DOI Link
18F-FDG as an inflammation biomarker for imaging dengue virus infection and treatment response. A. Chacko, S. Watanabe, K. Herr, S. Kalimuddin, J. Tham, J. Ong, M. Reolo, R. Serrano, Y. Cheung, J. Low, S. Vasudevan, May 2017, JCI insight, PubMed Link, DOI Link
Detection of micrometastases using SPECT/fluorescence dual-modality imaging in a CEA-expressing tumor model. M. Hekman, M. Rijpkema, D. Bos, E. Oosterwijk, D. Goldenberg, P. Mulders, O. Boerman, May 2017, Journal of Nuclear Medicine, PubMed Link, DOI Link
Non-diverging analytical expression for the sensitivity of converging SPECT collimators. J. Van Roosmalen, M. Goorden, April 2017, Physics in Medicine and Biology, PubMed Link, DOI Link
Use of cyclic backbone NGR-based SPECT to increase efficacy of postmyocardial infarction angiogenesis imaging. G. Hendrikx, T. Hackeng, R. Van Gorp, M. Bauwens, L. Schurgers, F. Mottaghy, M. Post, I. Dijkgraaf, 2017, Contrast Media and Molecular Imaging, PubMed Link, DOI Link
Evaluation of 99mTc-3PRGD2 integrin receptor imaging in hepatocellular carcinoma tumour-bearing mice: comparison with 18F-FDG metabolic imaging. J. Zheng, W. Miao, C. Huang, H. Lin, 2017, Annals of Nuclear Medicine, PubMed Link, DOI Link
Development and evaluation of a new modular nanotransporter for drug delivery into nuclei of pathological cells expressing folate receptors. T. Slastnikova, A. Rosenkranz, Y. Khramtsov, T. Karyagina, S. Ovechko, A. Sobolev, April 2017, Drug Design, Development and Therapy, PubMed Link, DOI Link
Multi-isotope SPECT imaging of the 225Ac decay chain: Feasibility studies. A. Robertson, C. Ramogida, C. Rodríguez-Rodríguez, S. Blinder, P. Kunz, V. Sossi, P. Schaffer, March 2017, Physics in Medicine and Biology, PubMed Link, DOI Link
Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging. B. Frigerio, G. Franssen, E. Luison, A. Satta, E. Seregni, M. Colombatti, G. Fracasso, R. Valdagni, D. Mezzanzanica, O. Boerman, S. Canevari, M. Figini, February 2017, Oncotarget, PubMed Link, DOI Link
Preclinical imaging characteristics and quantification of Platinum-195m SPECT. E. Aalbersberg, B. de Wit – van der Veen, O. Zwaagstra, K. Codée – van der Schilden, E. Vegt, W. Vogel, February 2017, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
68Ga/177Lu-NeoBOMB1, a novel radiolabeled GRPR antagonist for theranostic use in oncology. S. Dalm, I. Bakker, E. De Blois, G. Doeswijk, M. Konijnenberg, F. Orlandi, D. Barbato, M. Tedesco, T. Maina, B. Nock, M. De Jong, February 2017, Journal of Nuclear Medicine, PubMed Link, DOI Link
In vivo imaging of antileukemic drug asparaginase reveals a rapid macrophage-mediated clearance from the bone marrow. L. Van Der Meer, S. Terry, D. Van Ingen Schenau, K. Andree, G. Franssen, D. Roeleveld, J. Metselaar, T. Reinheckel, P. Hoogerbrugge, O. Boerman, F. Van Leeuwen, February 2017, Journal of Nuclear Medicine, PubMed Link, DOI Link
Activation of brain glucose metabolism ameliorating cognitive impairment in APP/PS1 transgenic mice by electroacupuncture. W. Liu, P. Zhuo, L. Li, H. Jin, B. Lin, Y. Zhang, S. Liang, J. Wu, J. Huang, Z. Wang, R. Lin, L. Chen, J. Tao, 2017, Free Radical Biology and Medicine, PubMed Link, DOI Link
High-Resolution 4D Preclinical Single-Photon Emission Computed Tomography/X-ray Computed Tomography Imaging of Technetium Transport within a Heterogeneous Porous Media. M. Dogan, S. Moysey, R. Ramakers, T. Devol, F. Beekman, H. Groen, B. Powell, January 2017, Environmental Science and Technology, PubMed Link, DOI Link
Preparation, cytotoxicity, and in vivo antitumor efficacy of 111in-labeled modular nanotransporters. T. Slastnikova, A. Rosenkranz, N. Morozova, M. Vorontsova, V. Petriev, T. Lupanova, A. Ulasov, M. Zalutsky, R. Yakubovskaya, A. Sobolev, January 2017, International Journal of Nanomedicine, PubMed Link, DOI Link

2016

Monitoring therapy response of experimental arthritis with radiolabeled tracers targeting fibroblasts, macrophages, or integrin αvβ3. S. Terry, M. Koenders, G. Franssen, T. Nayak, A. Freimoser-Grundschober, C. Klein, W. Oyen, O. Boerman, P. Laverman, December 2016, Journal of Nuclear Medicine, PubMed Link, DOI Link
Comparison of LDPI to SPECT perfusion imaging using 99mTc-sestamibi and 99mTc-pyrophosphate in a murine ischemic hind limb model of neovascularization. G. Hendrikx, M. Vries, M. Bauwens, M. De Saint-Hubert, A. Wagenaar, J. Guillaume, L. Boonen, M. Post, F. Mottaghy, December 2016, EJNMMI Research, PubMed Link, DOI Link
SPECT of Transplanted Islets of Langerhans by Dopamine 2 Receptor Targeting in a Rat Model. S. Willekens, I. Van Der Kroon, L. Joosten, C. Frielink, O. Boerman, S. Van Den Broek, M. Brom, M. Gotthardt, November 2016, Molecular Pharmaceutics, PubMed Link, DOI Link
Ultrasmall Biocompatible Bi2Se3 Nanodots for Multimodal Imaging-Guided Synergistic Radiophotothermal Therapy against Cancer. F. Mao, L. Wen, C. Sun, S. Zhang, G. Wang, J. Zeng, Y. Wang, J. Ma, M. Gao, Z. Li, November 2016, ACS Nano, PubMed Link, DOI Link
Novel 99mTc(III)-azide complexes [99mTc(N3)(CDO)(CDOH)2B-R] (CDOH2 = cyclohexanedione dioxime) as potential radiotracers for heart imaging. M. Liu, Y. Zheng, U. Avcibasi, S. Liu, November 2016, Nuclear Medicine and Biology, PubMed Link, DOI Link
Ambient Aqueous Synthesis of Ultrasmall PEGylated Cu2−xSe Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer. S. Zhang, C. Sun, J. Zeng, Q. Sun, G. Wang, Y. Wang, Y. Wu, S. Dou, M. Gao, Z. Li, October 2016, Advanced Materials, PubMed Link, DOI Link
Novel 99mTc(III) Complexes [99mTcCl(CDO)(CDOH)2B-R] (CDOH2 = Cyclohexanedione Dioxime) Useful as Radiotracers for Heart Imaging. M. Liu, W. Fang, S. Liu, October 2016, Bioconjugate Chemistry, PubMed Link, DOI Link
5-HT2A receptor SPECT imaging with [123I]R91150 under P-gp inhibition with tariquidar: More is better?. S. Tsartsalis, B. Tournier, T. Huynh-Gatz, N. Dumas, N. Ginovart, M. Moulin-Sallanon, P. Millet, September 2016, Nuclear Medicine and Biology, PubMed Link, DOI Link
Radionuclide imaging of liposomal drug delivery. T. van der Geest, P. Laverman, J. Metselaar, G. Storm, O. Boerman, September 2016, Expert Opinion on Drug Delivery, PubMed Link, DOI Link
Preclinical evaluation of [111In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity. C. Vangestel, D. Thomae, J. Van Soom, J. Ides, L. wyffels, P. Pauwels, S. Stroobants, P. Van der Veken, V. Magdolen, J. Joossens, K. Augustyns, S. Staelens, August 2016, Contrast Media and Molecular Imaging, PubMed Link, DOI Link
In vivo biodistribution of stable spherical and filamentous micelles probed by high-sensitivity SPECT. L. Jennings, O. Ivashchenko, I. Marsman, A. Laan, A. Denkova, G. Waton, F. Beekman, F. Schosseler, E. Mendes, August 2016, Biomaterials Science, PubMed Link, DOI Link
Molecular breast tomosynthesis with scanning focus multi-pinhole cameras. J. Van Roosmalen, M. Goorden, F. Beekman, August 2016, Physics in Medicine and Biology, PubMed Link, DOI Link
Improved Quantification of the Beta Cell Mass after Pancreas Visualization with 99mTc-demobesin-4 and Beta Cell Imaging with 111In-exendin-3 in Rodents. I. Van Der Kroon, L. Joosten, B. Nock, T. Maina, O. Boerman, M. Brom, M. Gotthardt, August 2016, Molecular Pharmaceutics, PubMed Link, DOI Link
High-resolution clustered pinhole 131Iodine SPECT imaging in mice. F. van der Have, O. Ivashchenko, M. Goorden, R. Ramakers, F. Beekman, August 2016, Nuclear Medicine and Biology, PubMed Link, DOI Link
Rhenium-188 Labeled Tungsten Disulfide Nanoflakes for Self-Sensitized, Near-Infrared Enhanced Radioisotope Therapy. Y. Chao, G. Wang, C. Liang, X. Yi, X. Zhong, J. Liu, M. Gao, K. Yang, L. Cheng, Z. Liu, August 2016, Small (Weinheim an der Bergstrasse, Germany), PubMed Link, DOI Link
Synthesis, in vitro and in vivo small-animal SPECT evaluation of novel technetium labeled bile acid analogues to study (altered) hepatic transporter function. S. Neyt, M. Vliegen, B. Verreet, S. De Lombaerde, K. Braeckman, C. Vanhove, M. Huisman, C. Dumolyn, K. Kersemans, F. Hulpia, S. Van Calenbergh, G. Mannens, F. De Vos, July 2016, Nuclear Medicine and Biology, PubMed Link, DOI Link
Ultrasmall biocompatible WO3−x nanodots for multi-modality imaging and combined therapy of cancers. L. Wen, L. Chen, S. Zheng, J. Zeng, G. Duan, Y. Wang, G. Wang, Z. Chai, Z. Li, M. Gao, July 2016, Advanced Materials, PubMed Link, DOI Link
Pre-clinical Evaluation of a Cyanine-Based SPECT Probe for Multimodal Tumor Necrosis Imaging. M. Stammes, V. Knol-Blankevoort, L. Cruz, H. Feitsma, L. Mezzanotte, R. Cordfunke, R. Sinisi, E. Dubikovskaya, A. Maeda, R. DaCosta, K. Bierau, A. Chan, E. Kaijzel, T. Snoeks, E. van Beek, C. Löwik, June 2016, Molecular Imaging and Biology, PubMed Link, DOI Link
Similarity-regulation of OS-EM for accelerated SPECT reconstruction. P. Vaissier, F. Beekman, M. Goorden, June 2016, Physics in Medicine and Biology, PubMed Link, DOI Link
Tailoring Fluorescent Dyes to Optimize a Hybrid RGD-Tracer. A. Bunschoten, D. Van Willigen, T. Buckle, N. Van Den Berg, M. Welling, S. Spa, H. Wester, F. Van Leeuwen, May 2016, Bioconjugate Chemistry, PubMed Link, DOI Link
Optimizing modelling in iterative image reconstruction for preclinical pinhole PET. M. Goorden, J. Van Roosmalen, F. Van Der Have, F. Beekman, April 2016, Physics in Medicine and Biology, PubMed Link, DOI Link
Linksventrikuläre funktionsmessungen in einem myokardinfarkt-tiermodell: Vergleich zwischen 3D-echokardiographie und EKG-getriggerte SPECT. G. Hendrikx, M. Bauwens, R. Wierts, F. Mottaghy, M. Post, April 2016, NuklearMedizin, PubMed Link, DOI Link
Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography. J. Lalut, B. Tournier, T. Cailly, C. Lecoutey, S. Corvaisier, A. Davis, C. Ballandonne, M. Since, P. Millet, F. Fabis, P. Dallemagne, C. Rochais, March 2016, European Journal of Medicinal Chemistry, PubMed Link, DOI Link
Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia. W. Shen, M. Patnaik, A. Ruiz, S. Russell, K. Peng, March 2016, Blood, PubMed Link, DOI Link
Utilizing high-energy γ-photons for high-resolution 213Bi SPECT in mice. J. De Swart, H. Chan, M. Goorden, A. Morgenstern, F. Bruchertseifer, F. Beekman, M. De Jong, M. Konijnenberg, March 2016, Journal of Nuclear Medicine, PubMed Link, DOI Link
SPECT/CT Imaging of Pluronic Nanocarriers with Varying Poly(ethylene oxide) Block Length and Aggregation State. A. Arranja, O. Ivashchenko, A. Denkova, K. Morawska, S. Van Vlierberghe, P. Dubruel, G. Waton, F. Beekman, F. Schosseler, E. Mendes, February 2016, Molecular Pharmaceutics, PubMed Link, DOI Link
Radiolabeled cyclic RGD peptides as radiotracers for tumor imaging. J. Shi, F. Wang, S. Liu, February 2016, Biophysics Reports, PubMed Link, DOI Link
Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. K. Kanazaki, K. Sano, A. Makino, F. Yamauchi, A. Takahashi, T. Homma, M. Ono, H. Saji, February 2016, Journal of Controlled Release, PubMed Link, DOI Link
Early prediction of tumor response to treatment: Preclinical validation of 99mTc-Duramycin. F. Elvas, C. Vangestel, K. Pak, P. Vermeulen, B. Gray, S. Stroobants, S. Staelens, L. Wyffels, February 2016, Journal of Nuclear Medicine, PubMed Link, DOI Link
Noninvasive imaging of islet transplants with 111In-Exendin-3 SPECT/CT. I. Van Der Kroon, K. Andralojc, S. Willekens, D. Bos, L. Joosten, O. Boerman, M. Brom, M. Gotthardt, January 2016, Journal of Nuclear Medicine, PubMed Link, DOI Link
Imaging, biodistribution, and dosimetry of radionuclide-labeled PD-L1 antibody in an immunocompetent mouse model of breast cancer. A. Josefsson, J. Nedrow, S. Park, S. Banerjee, A. Rittenbach, F. Jammes, B. Tsui, G. Sgouros, January 2016, Cancer Research, PubMed Link, DOI Link
SPECT vs. PET monitoring of bone defect healing and biomaterial performance in vivo. M. Ventura, G. Franssen, E. Oosterwijk, O. Boerman, J. Jansen, X. Walboomers, January 2016, Journal of Tissue Engineering and Regenerative Medicine, PubMed Link, DOI Link
Comparison of biological properties of 99mTc-labeled cyclic RGD Peptide trimer and dimer useful as SPECT radiotracers for tumor imaging. Z. Zhao, Y. Yang, W. Fang, S. Liu, 2016, Nuclear Medicine and Biology, PubMed Link, DOI Link
SPECT-OPT multimodal imaging enables accurate evaluation of radiotracers for β-cell mass assessments. W. Eter, S. Parween, L. Joosten, C. Frielink, M. Eriksson, M. Brom, U. Ahlgren, M. Gotthardt, January 2016, Scientific Reports, PubMed Link, DOI Link
Towards personalized treatment of prostate cancer: PSMA I&T, a promising prostate-specific membrane antigen-targeted theranostic agent. K. Chatalic, S. Heskamp, M. Konijnenberg, J. Molkenboer-Kuenen, G. Franssen, M. Clahsen-van Groningen, M. Schottelius, H. Wester, W. van Weerden, O. Boerman, M. de Jong, January 2016, Theranostics, PubMed Link, DOI Link

2015

In Vivo Simultaneous Imaging of Vascular Pool and Hypoxia with a HT-29 Tumor Model: the Application of Dual-Isotope SPECT/PET/CT. N. Adachi, Y. Yoshii, T. Furukawa, M. Yoshimoto, Y. Takeuchi, M. Inubushi, H. Wakizaka, M. Zang, A. Tsuji, M. Takahashi, Y. Fujibayashi, T. Saga, December 2015, International Journal of Sciences: Basic and Applied Research (IJSBAR)
111In-Cetuximab-F(ab′)2 SPECT and 18F-FDG PET for prediction and response monitoring of combined-modality treatment of human head and neck carcinomas in a mouse model. L. Van Dijk, O. Boerman, G. Franssen, J. Kaanders, J. Bussink, December 2015, Journal of Nuclear Medicine, PubMed Link, DOI Link
Noninvasive 3-dimensional imaging of liver regeneration in a mouse model of hereditary tyrosinemia type 1 using the sodium iodide symporter gene. R. Hickey, S. Mao, B. Amiot, L. Suksanpaisan, A. Miller, R. Nace, J. Glorioso, M. O’Connor, K. Peng, Y. Ikeda, S. Russell, S. Nyberg, December 2015, Liver Transplantation, PubMed Link, DOI Link
Polydopamine as a Biocompatible Multifunctional Nanocarrier for Combined Radioisotope Therapy and Chemotherapy of Cancer. X. Zhong, K. Yang, Z. Dong, X. Yi, Y. Wang, C. Ge, Y. Zhao, Z. Liu, December 2015, Advanced Functional Materials, DOI Link
Biodistribution of Fracture-Targeted GSK3β Inhibitor-Loaded Micelles for Improved Fracture Healing. S. Low, C. Galliford, J. Yang, P. Low, J. Kopeček, October 2015, Biomacromolecules, PubMed Link, DOI Link
Comparison of three remote radiolabelling methods for long-circulating liposomes. T. Van Der Geest, P. Laverman, D. Gerrits, G. Franssen, J. Metselaar, G. Storm, O. Boerman, 2015, Journal of Controlled Release, PubMed Link, DOI Link
Graft revascularization is essential for non-invasive monitoring of transplanted islets with radiolabeled exendin. W. Eter, D. Bos, C. Frielink, O. Boerman, M. Brom, M. Gotthardt, 2015, Scientific Reports, PubMed Link, DOI Link
Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake. M. Rotman, M. Welling, M. van den Boogaard, L. Moursel, L. van der Graaf, M. van Buchem, S. van der Maarel, L. van der Weerd, August 2015, Nuclear Medicine and Biology, PubMed Link, DOI Link
Radioiodinated peptidic imaging probes for in vivo detection of membrane type-1 matrix metalloproteinase in cancers. N. Kondo, T. Temma, Y. Shimizu, M. Ono, H. Saji, 2015, Biological and Pharmaceutical Bulletin, PubMed Link, DOI Link
Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging. K. Van Audenhaege, R. Van Holen, S. Vandenberghe, C. Vanhove, S. Metzler, S. Moore, 2015, Medical Physics, PubMed Link, DOI Link
Oncolytic measles virus as a novel therapy for malignant peripheral nerve sheath tumors. D. Deyle, D. Escobar, K. Peng, D. Babovic-Vuksanovic, July 2015, Gene, PubMed Link, DOI Link
Performance characteristics of a novel clustered multi-pinhole technology for simultaneous high-resolution SPECT/PET. K. Miwa, M. Inubushi, Y. Takeuchi, T. Katafuchi, M. Koizumi, T. Saga, M. Sasaki, June 2015, Annals of Nuclear Medicine, PubMed Link, DOI Link
111In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages. S. Terry, O. Boerman, D. Gerrits, G. Franssen, J. Metselaar, S. Lehmann, W. Oyen, C. Gerdes, K. Abiraj, May 2015, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
Noninvasive imaging of tumor PD-L1 expression using radiolabeled Anti-PD-L1 antibodies. S. Heskamp, W. Hobo, J. Molkenboer-Kuenen, D. Olive, W. Oyen, H. Dolstra, O. Boerman, May 2015, Cancer Research, PubMed Link, DOI Link
Drug composition matters: The influence of carrier concentration on the radiochemical purity, hydroxyapatite affinity and in-vivo bone accumulation of the therapeutic radiopharmaceutical 188Rhenium-HEDP. R. Lange, J. de Klerk, H. Bloemendal, R. Ramakers, F. Beekman, M. van der Westerlaken, N. Hendrikse, R. ter Heine, May 2015, Nuclear Medicine and Biology, PubMed Link, DOI Link
Characterization of [99mTc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis. F. Elvas, C. Vangestel, S. Rapic, J. Verhaeghe, B. Gray, K. Pak, S. Stroobants, S. Staelens, L. wyffels, April 2015, Molecular Imaging and Biology, PubMed Link, DOI Link
Immuno-PET and immuno-SPECT of rheumatoid arthritis with radiolabeled anti-fibroblast activation protein antibody correlates with severity of arthritis. P. Laverman, T. Van Der Geest, S. Terry, D. Gerrits, B. Walgreen, M. Helsen, T. Nayak, A. Freimoser-Grundschober, I. Waldhauer, R. Hosse, E. Moessner, P. Umana, C. Klein, W. Oyen, M. Koenders, O. Boerman, April 2015, Journal of Nuclear Medicine, PubMed Link, DOI Link
Development of a Hybrid Tracer for SPECT and Optical Imaging of Bacterial Infections. M. Welling, A. Bunschoten, J. Kuil, R. Nelissen, F. Beekman, T. Buckle, F. Van Leeuwen, April 2015, Bioconjugate Chemistry, PubMed Link, DOI Link
uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery. M. Boonstra, P. van Driel, D. van Willigen, M. Stammes, H. Prevoo, Q. Tummers, A. Mazar, F. Beekman, P. Kuppen, C. van de Velde, C. Löwik, J. Frangioni, F. van Leeuwen, C. Sier, A. Vahrmeijer, March 2015, Oncotarget, PubMed Link, DOI Link
SPECT imaging of glioma with radioiodinated CLINDE: Evidence from a mouse GL26 glioma model. S. Tsartsalis, N. Dumas, B. Tournier, T. Pham, M. Moulin-Sallanon, M. Grégoire, Y. Charnay, P. Millet, March 2015, EJNMMI Research, PubMed Link, DOI Link
99mTc Radiolabeling and Biological Evaluation of Nanoparticles Functionalized with a Versatile Coating Ligand. M. Felber, M. Bauwens, J. Mateos, S. Imstepf, F. Mottaghy, R. Alberto, March 2015, Chemistry – A European Journal, PubMed Link, DOI Link
Design of a serotonin 4 receptor radiotracer with decreased lipophilicity for single photon emission computed tomography. N. Fresneau, N. Dumas, B. Tournier, C. Fossey, C. Ballandonne, A. Lesnard, P. Millet, Y. Charnay, T. Cailly, J. Bouillon, F. Fabis, March 2015, European Journal of Medicinal Chemistry, PubMed Link, DOI Link
Radionuclide and Fluorescence Imaging of Clear Cell Renal Cell Carcinoma Using Dual Labeled Anti-Carbonic Anhydrase IX Antibody G250. C. Muselaers, M. Rijpkema, D. Bos, J. Langenhuijsen, W. Oyen, P. Mulders, E. Oosterwijk, O. Boerman, February 2015, Journal of Urology, PubMed Link, DOI Link
Ultra-high-sensitivity submillimeter mouse SPECT. O. Ivashchenko, F. Van Der Have, M. Goorden, R. Ramakers, F. Beekman, February 2015, Journal of Nuclear Medicine, PubMed Link, DOI Link
G-SPECT-I: a full ring high sensitivity and ultra-fast clinical molecular imaging system with < 3mm resolution. F. Beekman, M. Goorden, P. Vaissier, J. van Roosmalen, H. During, B. Vastenhouw, 2015, Eur J NuclMed Mol Imaging
Impact of boronate capping groups on biological characteristics of novel 99mTc(III) complexes [99mTcCl(CDO)(CDOH)2B-R] (CDOH2 = cyclohexanedione dioxime). Y. Yang, Y. Zheng, E. Tomaselli, W. Fang, S. Liu, January 2015, Bioconjugate Chemistry, PubMed Link, DOI Link
Central delivery of iodine-125-labeled cetuximab, etanercept and anakinra after perispinal injection in rats: Possible implications for treating Alzheimer’s disease. M. Roerink, R. Groen, G. Franssen, B. Lemmers-Van De Weem, O. Boerman, J. Van Der Meer, January 2015, Alzheimer’s Research and Therapy, PubMed Link, DOI Link
Evaluation of a nonpeptidic ligand for imaging of cholecystokinin 2 receptor-expressing cancers. C. Wayua, P. Low, January 2015, Journal of Nuclear Medicine, PubMed Link, DOI Link
Molecular imaging of angiogenesis after myocardial infarction by 111In-DTPA-cNGR and 99mTc-sestamibi dual-isotope myocardial SPECT. G. Hendrikx, M. De Saint-Hubert, I. Dijkgraaf, M. Bauwens, K. Douma, R. Wierts, I. Pooters, N. Van den Akker, T. Hackeng, M. Post, F. Mottaghy, January 2015, EJNMMI Research, PubMed Link, DOI Link
In vivo quantification of 5-HT2A brain receptors in Mdr1a KO rats with 123I-R91150 single-photon emission computed tomography. N. Dumas, M. Moulin-Sallanon, P. Fender, B. Tournier, N. Ginovart, Y. Charnay, P. Millet, January 2015, Molecular Imaging, PubMed Link, DOI Link

2014

Folate receptor-β imaging using 99mTc-folate to explore distribution of polarized macrophage populations in human atherosclerotic plaque. N. Jager, J. Westra, R. Golestani, G. Van Dam, P. Low, R. Tio, R. Slart, H. Boersma, M. Bijl, C. Zeebregts, December 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
Quarter-millimeter-resolution molecular mouse imaging with U-SPECT⁺. O. Ivashchenko, F. van der Have, J. Villena, H. Groen, R. Ramakers, H. Weinans, F. Beekman, November 2014, Molecular imaging, PubMed Link, DOI Link
Pretargeted dual-modality immuno-spect and near-infrared fluorescence imaging for image-guided surgery of prostate cancer. S. Lütje, M. Rijpkema, D. Goldenberg, C. Van Rij, R. Sharkey, W. McBride, G. Franssen, C. Frielink, W. Helfrich, W. Oyen, O. Boerman, November 2014, Cancer Research, PubMed Link, DOI Link
Influence of respiratory gating, image filtering, and animal positioning on high-resolution electrocardiography-gated murine cardiac single-photon emission computed tomography. C. Wu, P. Vaissier, B. Vastenhouw, J. de Jong, R. Slart, F. Beekman, November 2014, Molecular imaging, PubMed Link, DOI Link
Can 111In-RGD2 monitor response to therapy in head and neck tumor xenografts?. S. Terry, K. Abiraj, J. Lok, D. Gerrits, G. Franssen, W. Oyen, O. Boerman, November 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
Early response monitoring with 18F-FDG PET and cetuximab-F(ab′)2-SPECT after radiotherapy of human head and neck squamous cell carcinomas in a mouse model. L. Van Dijk, O. Boerman, G. Franssen, J. Lok, J. Kaanders, J. Bussink, October 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
Impact of Multiple Negative Charges on Blood Clearance and Biodistribution Characteristics of 99mTc-Labeled Dimeric Cyclic RGD Peptides. Y. Yang, S. Ji, S. Liu, September 2014, Bioconjugate Chemistry, PubMed Link, DOI Link
High-resolution Medium-sized Animal Multi-pinhole SPECT with Stationary Detectors. F. van der Have, O. Ivashchenko, H. Groen, R. Ramakers, H. During, F. Beekman, 2014, Eur J Nucl Med Mol Imaging
In vivo and in vitro evidence that 99mTc-HYNIC-interleukin-2 is able to detect T lymphocytes in vulnerable atherosclerotic plaques of the carotid artery. A. Glaudemans, E. Bonanno, F. Galli, C. Zeebregts, E. De Vries, M. Koole, G. Luurtsema, H. Boersma, M. Taurino, R. Slart, A. Signore, September 2014, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
SPECT- and fluorescence image-guided surgery using a dual-labeled carcinoembryonic antigen-targeting antibody. M. Rijpkema, W. Oyen, D. Bos, G. Franssen, D. Goldenberg, O. Boerman, September 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
Micro-CT of rodents: State-of-the-art and future perspectives. D. Clark, C. Badea, September 2014, Physica Medica, PubMed Link, DOI Link
Dynamics of IGF-1R expression during endocrine breast cancer treatment. S. Heskamp, O. Boerman, J. Molkenboer-Kuenen, R. Koornstra, S. Linn, W. Oyen, W. Van Der Graaf, H. Van Laarhoven, August 2014, Molecular Imaging and Biology, PubMed Link, DOI Link
Cetuximab reduces the accumulation of radiolabeled bevacizumab in cancer xenografts without decreasing VEGF expression. S. Heskamp, O. Boerman, J. Molkenboer-Kuenen, F. Sweep, A. Geurts-Moespot, M. Engelhardt, W. Van Der Graaf, W. Oyen, H. Van Laarhoven, 2014, Molecular Pharmaceutics, PubMed Link, DOI Link
Anatomical and functional imaging of myocardial infarction in mice using micro-CT and eXIA 160 contrast agent. J. Ashton, N. Befera, D. Clark, Y. Qi, L. Mao, H. Rockman, G. Johnson, C. Badea, 2014, Contrast Media and Molecular Imaging, PubMed Link, DOI Link
Development of kit formulations for 99mTcN-MPO: A cationic radiotracer for myocardial perfusion imaging. Y. Zheng, S. Ji, E. Tomaselli, S. Liu, July 2014, Journal of Labelled Compounds and Radiopharmaceuticals, PubMed Link, DOI Link
Performance assessment of a preclinical PET scanner with pinhole collimation by comparison to a coincidence-based small-animal PET scanner. M. Walker, M. Goorden, K. Dinelle, R. Ramakers, S. Blinder, M. Shirmohammad, F. Van Der Have, F. Beekman, V. Sossi, June 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
The role of Preclinical SPECT in oncological and neurological research in combination with either CT or MRI. M. Bernsen, P. Vaissier, R. Van Holen, J. Booij, F. Beekman, M. De Jong, May 2014, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
Three-dimensional histologic validation of high-resolution spect of antibody distributions within xenografts. W. Branderhorst, E. Blezer, M. Houtkamp, R. Ramakers, J. Van Den Brakel, H. Witteveen, F. Van Der Have, H. Van Andel, B. Vastenhouw, C. Wu, M. Stigter-vanWalsum, G. Van Dongen, M. Viergever, W. Bleeker, F. Beekman, May 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
Bench to bedside development of GMP grade Rhenium-188-HEDP, a radiopharmaceutical for targeted treatment of painful bone metastases. R. Ter Heine, R. Lange, O. Breukels, H. Bloemendal, R. Rummenie, A. Wakker, H. De Graaf, F. Beekman, M. Van Der Westerlaken, M. Malingré, J. Wielders, L. Van Den Berg, N. Hendrikse, J. De Klerk, April 2014, International Journal of Pharmaceutics, PubMed Link, DOI Link
Dual-modality image-guided surgery of prostate cancer with a radiolabeled fluorescent anti-PSMA monoclonal antibody. S. Lütje, M. Rijpkema, G. Franssen, G. Fracasso, W. Helfrich, A. Eek, W. Oyen, M. Colombatti, O. Boerman, April 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
Comparison of 4D-MicroSPECT and MicroCT for murine cardiac function. N. Befera, C. Badea, G. Johnson, April 2014, Molecular Imaging and Biology, PubMed Link, DOI Link
OAT3-mediated extrusion of the 99mTc-ECD metabolite in the mouse brain. T. Kikuchi, T. Okamura, H. Wakizaka, M. Okada, K. Odaka, J. Yui, A. Tsuji, T. Fukumura, M. Zhang, April 2014, Journal of Cerebral Blood Flow and Metabolism, PubMed Link, DOI Link
Assessing cardiac injury in mice with dual energy-MicroCT, 4D-MicroCT, and MicroSPECT imaging after partial heart irradiation. C. Lee, H. Min, N. Befera, D. Clark, Y. Qi, S. Das, G. Johnson, C. Badea, D. Kirsch, March 2014, International Journal of Radiation Oncology Biology Physics, PubMed Link, DOI Link
Oncolytic vaccinia virotherapy for endometrial cancer. Y. Liu, J. Wang, V. Avanzato, J. Bakkum-Gamez, S. Russell, J. Bell, K. Peng, March 2014, Gynecologic Oncology, PubMed Link, DOI Link
Imaging integrin αvβ3 on blood vessels with 111In-RGD2 in head and neck tumor xenografts. S. Terry, K. Abiraj, C. Frielink, L. Van Dijk, J. Bussink, W. Oyen, O. Boerman, February 2014, Journal of Nuclear Medicine, PubMed Link, DOI Link
Small-animal single-photon emission computed tomographic imaging of the brain serotoninergic systems in wild-type and Mdr1a knockout rats. N. Dumas, M. Moulin-Sallanon, N. Ginovart, B. Tournier, P. Suzanne, T. Cailly, F. Fabis, S. Rault, Y. Charnay, P. Millet, 2014, Molecular Imaging, PubMed Link, DOI Link
Combination of single-photon emission computed tomography and magnetic resonance imaging to track 111in-oxine-labeled human mesenchymal stem cells in neuroblastoma-bearing mice. L. Cussó, I. Mirones, S. Peña-Zalbidea, V. García-Vázquez, J. García-Castro, M. Desco, January 2014, Molecular Imaging, PubMed Link, DOI Link
Optimizing lutetium 177-anti-carbonic anhydrase ix radioimmunotherapy in an intraperitoneal clear cell renal cell carcinoma xenograft model. C. Muselaers, E. Oosterwijk, D. Bos, W. Oyen, P. Mulders, O. Boerman, January 2014, Molecular Imaging, PubMed Link, DOI Link

2013

Microdistribution of MC1R-targeted polyplexes in murine melanoma tumor tissue. M. Durymanov, T. Slastnikova, A. Kuzmich, Y. Khramtsov, A. Ulasov, A. Rosenkranz, S. Egorov, E. Sverdlov, A. Sobolev, December 2013, Biomaterials, PubMed Link, DOI Link
Imaging of epidermal growth factor receptor expression in head and neck cancer with SPECT/CT and 111In-labeled cetuximab-F(ab′) 2. L. Van Dijk, B. Hoeben, J. Kaanders, G. Franssen, O. Boerman, J. Bussink, December 2013, Journal of Nuclear Medicine, PubMed Link, DOI Link
Measles Virus entry through the signaling lymphocyte activation molecule governs efficacy of mantle cell lymphoma radiovirotherapy. T. Miest, M. Frenzke, R. Cattaneo, November 2013, Molecular Therapy, PubMed Link, DOI Link
Oral contrast enhances the resolution of in-life NIS reporter gene imaging. L. Suksanpaisan, L. Pham, S. McIvor, S. Russell, K. Peng, November 2013, Cancer Gene Therapy, PubMed Link, DOI Link
99mTc-Galacto-RGD2: A novel 99mTc-labeled cyclic RGD peptide dimer useful for tumor imaging. S. Ji, A. Czerwinski, Y. Zhou, G. Shao, F. Valenzuela, P. Sowiński, S. Chauhan, M. Pennington, S. Liu, September 2013, Molecular Pharmaceutics, PubMed Link, DOI Link
111In-cetuximab-F(ab’)2 SPECT imaging for quantification of accessible epidermal growth factor receptors (EGFR) in HNSCC xenografts. L. Van Dijk, B. Hoeben, H. Stegeman, J. Kaanders, G. Franssen, O. Boerman, J. Bussink, September 2013, Radiotherapy and Oncology, PubMed Link, DOI Link
The strength of small: Improved targeting of Insulin-like Growth Factor-1 Receptor (IGF-1R) with F(ab′)2-R1507 fragments in Ewing sarcomas. E. Fleuren, Y. Versleijen-Jonkers, S. Heskamp, M. Roeffen, W. Bouwman, J. Molkenboer-Kuenen, H. Van Laarhoven, W. Oyen, O. Boerman, W. Van Der Graaf, September 2013, European Journal of Cancer, PubMed Link, DOI Link
Fast count-regulated osem reconstruction with adaptive resolution recovery. P. Vaissier, M. Goorden, A. Taylor, F. Beekman, August 2013, IEEE Transactions on Medical Imaging, PubMed Link, DOI Link
Monitoring tumor response to linifanib therapy with SPECT/CT using the integrin αvβ3-Targeted Radiotracer 99mTc-3P- RGD2. S. Ji, Y. Zhou, M. Voorbach, G. Shao, Y. Zhang, G. Fox, D. Albert, Y. Luo, S. Liu, S. Mudd, August 2013, Journal of Pharmacology and Experimental Therapeutics, PubMed Link, DOI Link
Bevacizumab reduces tumor targeting of antiepidermal growth factor and anti-insulin-like growth factor 1 receptor antibodies. S. Heskamp, O. Boerman, J. Molkenboer-Kuenen, W. Oyen, W. Van Der Graaf, H. Van Laarhoven, July 2013, International Journal of Cancer, PubMed Link, DOI Link
Quantifying the effect of repetitive transcranial magnetic stimulation in the rat brain by μsPECT CBF scans. T. Wyckhuys, N. De Geeter, G. Crevecoeur, S. Stroobants, S. Staelens, July 2013, Brain Stimulation, PubMed Link, DOI Link
Use of folate-conjugated imaging agents to target alternatively activated macrophages in a murine model of asthma. J. Shen, V. Chelvam, G. Cresswell, P. Low, May 2013, Molecular Pharmaceutics, PubMed Link, DOI Link
Whole-body sub-half-minute 4D pharmacokinetic SPECT in mice [Computer software]. R. Ramakers, B. Vastenhouw, P. Vaissier, F. Beekman, May 2013, Journal of Nuclear Medicine
Performance evaluation of small-animal multipinhole μsPECT scanners for mouse imaging. S. Deleye, R. Van Holen, J. Verhaeghe, S. Vandenberghe, S. Stroobants, S. Staelens, May 2013, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
Integration of small animal SPECT and PET with other imaging modalities. P. Vaissier, C. Wu, F. Beekman, 2013, Tijdschrift voor Nucleaire Geneeskunde
Miniaturized antibodies for imaging membrane type-1 matrix metalloproteinase in cancers. N. Kondo, T. Temma, Y. Shimizu, H. Watanabe, K. Higano, Y. Takagi, M. Ono, H. Saji, April 2013, Cancer Science, PubMed Link, DOI Link
In vivo visualization and quantification of (disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc- mebrofenin in mice. S. Neyt, M. Huisman, C. Vanhove, H. De Man, M. Vliegen, L. Moerman, C. Dumolyn, G. Mannens, F. De Vos, April 2013, Journal of Nuclear Medicine, PubMed Link, DOI Link
Optimizing image reconstruction for simultaneous sub-mm clustered pinhole PET-SPECT. M. Goorden, F. Beekman, 2013, Proceedings of the 12th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine
High Resolution microSPECT imaging of Bi-213. J. Swart, M. Segbers, A. Morgenstern, F. Have, H. Chan, S. Berndsen, F. Bruchertseifer, M. Jong, F. Beekman, M. Konijnenberg, 2013, Eanm
Monitoring glioma growth and tumor necrosis with the U-SPECT-II/CT scanner by targeting integrin αvβ3. G. Shao, Y. Zhou, F. Wang, S. Liu, 2013, Molecular Imaging, PubMed Link, DOI Link
Evaluation of a technetium-99m labeled bombesin homodimer for GRPR imaging in prostate cancer. Z. Yu, G. Carlucci, H. Ananias, R. Dierckx, S. Liu, W. Helfrich, F. Wang, I. De Jong, P. Elsinga, February 2013, Amino Acids, PubMed Link, DOI Link
VECTor: A preclinical imaging system for simultaneous submillimeter SPECT and PET. M. Goorden, . Frans van der Have, R. Kreuger, R. Ramakers, B. Vastenhouw, J. Burbach, J. Booij, C. Molthoff, F. Beekman, February 2013, Journal of Nuclear Medicine, PubMed Link, DOI Link
Development and characterization of [123I]iodotiagabine for in-vivo GABA-transporter imaging. O. Schijns, M. Van Kroonenburgh, F. Beekman, J. Verbeek, J. Herscheid, K. Rijkers, V. Visser-Vandewalle, G. Hoogland, February 2013, Nuclear Medicine Communications, PubMed Link, DOI Link
Intratumoral Administration of Holmium-166 Acetylacetonate Microspheres: Antitumor Efficacy and Feasibility of Multimodality Imaging in Renal Cancer. W. Bult, S. Kroeze, M. Elschot, P. Seevinck, F. Beekman, H. de Jong, D. Uges, J. Kosterink, P. Luijten, W. Hennink, A. van het Schip, J. Bosch, J. Nijsen, J. Jans, January 2013, PLoS ONE, PubMed Link, DOI Link
Natural Killer Cells Generated from Cord Blood Hematopoietic Progenitor Cells Efficiently Target Bone Marrow-Residing Human Leukemia Cells in NOD/SCID/IL2Rgnull Mice. J. Cany, A. van der Waart, M. Tordoir, G. Franssen, B. Hangalapura, J. de Vries, O. Boerman, N. Schaap, R. van der Voort, J. Spanholtz, H. Dolstra, January 2013, PLoS ONE, PubMed Link, DOI Link
Effects of attenuation map accuracy on attenuation-corrected micro-SPECT images. C. Wu, H. van Andel, P. Laverman, O. Boerman, F. Beekman, January 2013, EJNMMI Research, PubMed Link, DOI Link

2012

Differential loading methods for BMP-2 within injectable calcium phosphate cement. F. Van De Watering, J. Molkenboer-Kuenen, O. Boerman, J. Van Den Beucken, J. Jansen, December 2012, Journal of Controlled Release, PubMed Link, DOI Link
Quantitative immuno-SPECT monitoring of pretargeted radioimmunotherapy with a bispecific antibody in an intraperitoneal nude mouse model of human colon cancer. R. Schoffelen, W. Van Der Graaf, R. Sharkey, G. Franssen, W. McBride, C. Chang, D. Bos, D. Goldenberg, W. Oyen, O. Boerman, December 2012, Journal of Nuclear Medicine, PubMed Link, DOI Link
Optimization of IGF-1R SPECT/CT imaging using 111in-labeled F(ab)2 and Fab fragments of the monoclonal antibody R1507. S. Heskamp, H. Van Laarhoven, J. Molkenboer-Kuenen, W. Bouwman, W. Van Der Graaf, W. Oyen, O. Boerman, August 2012, Molecular Pharmaceutics, PubMed Link, DOI Link
Radiolabeled gelatin type B analogues can be used for non-invasive visualisation and quantification of protein coatings on 3D porous implants. K. Kersemans, T. Desmet, C. Vanhove, P. Dubruel, F. De Vos, August 2012, Journal of Materials Science: Materials in Medicine, PubMed Link, DOI Link
Fast spiral SPECT with stationary γ-cameras and focusing pinholes. P. Vaissier, M. Goorden, B. Vastenhouw, F. Van Der Have, R. Ramakers, F. Beekman, August 2012, Journal of Nuclear Medicine, PubMed Link, DOI Link
Sub-millimeter I-131 SPECT with clustered pinholes. F. van der Have, M. Goorden, R. Kreuger, R. Ramakers, F. Beekman, 2012, Wmic
Varenicline increases in vivo striatal dopamine D2/3 receptor binding: An ultra-high-resolution pinhole [123I]IBZM SPECT study in rats. C. Crunelle, T. De Wit, K. De Bruin, R. Ramakers, F. Van der Have, F. Beekman, W. Van den Brink, J. Booij, July 2012, Nuclear Medicine and Biology, PubMed Link, DOI Link
A folate receptor-α-specific ligand that targets cancer tissue and not sites of inflammation. B. Vaitilingam, V. Chelvam, S. Kularatne, S. Poh, W. Ayala-Lopez, P. Low, July 2012, Journal of Nuclear Medicine, PubMed Link, DOI Link
Single-photon emission computed tomographic imaging of the early time course of therapy-induced cell death using technetium 99m tricarbonyl his-annexin A5 in a colorectal cancer xenograft model. C. Vangestel, C. Van De Wiele, G. Mees, K. Mertens, S. Staelens, C. Reutelingsperger, P. Pauwels, N. Van Damme, M. Peeters, April 2012, Molecular Imaging, PubMed Link, DOI Link
Murine cardiac images obtained with focusing pinhole SPECT are barely influenced by extra-cardiac activity. W. Branderhorst, F. Van Der Have, B. Vastenhouw, M. Viergever, F. Beekman, February 2012, Physics in Medicine and Biology, PubMed Link, DOI Link
In vitro and in vivo characterization of three 68ga-and 111in-labeled peptides for cholecystokinin receptor imaging. S. Roosenburg, P. Laverman, L. Joosten, A. Eek, F. Rutjes, F. Van Delft, O. Boerman, 2012, Molecular Imaging, PubMed Link, DOI Link
Radiolabelled peptides for oncological diagnosis. P. Laverman, J. Sosabowski, O. Boerman, W. Oyen, February 2012, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
Imaging of human epidermal growth factor receptor type 2 expression with 18F-labeled affibody molecule Z HER2:2395 in a mouse model for ovarian cancer. S. Heskamp, P. Laverman, D. Rosik, F. Boschetti, W. Van Der Graaf, W. Oyen, H. Van Laarhoven, V. Tolmachev, O. Boerman, January 2012, Journal of Nuclear Medicine, PubMed Link, DOI Link
Monitoring Breast Tumor Lung Metastasis by U-SPECT-II/CT with an Integrin α vβ 3-Targeted Radiotracer 99mtc-3P-RGD 2. Y. Zhou, G. Shao, S. Liu, January 2012, Theranostics, PubMed Link, DOI Link

2011

Predicting IGF-1R therapy response in bone sarcomas: Immuno-SPECT imaging with radiolabeled R1507. E. Fleuren, Y. Versleijen-Jonkers, A. Van De Luijtgaarden, J. Molkenboer-Kuenen, S. Heskamp, M. Roeffen, H. Van Laarhoven, P. Houghton, W. Oyen, O. Boerman, W. Van Der Graaf, December 2011, Clinical Cancer Research, PubMed Link, DOI Link
99mTc-(CO)3 His-annexin A5 micro-SPECT demonstrates increased cell death by irinotecan during the vascular normalization window caused by bevacizumab. C. Vangestel, C. Van De Wiele, N. Van Damme, S. Staelens, P. Pauwels, C. Reutelingsperger, M. Peeters, November 2011, Journal of Nuclear Medicine, PubMed Link, DOI Link
Using the NEMA NU 4 PET image quality phantom in multipinhole small-animal SPECT. A. Harteveld, A. Meeuwis, J. Disselhorst, C. Slump, W. Oyen, O. Boerman, E. Visser, October 2011, Journal of Nuclear Medicine, PubMed Link, DOI Link
Imaging of prostate cancer with immuno-PET and immuno-SPECT using a radiolabeled anti-EGP-1 monoclonal antibody. C. Van Rij, R. Sharkey, D. Goldenberg, C. Frielink, J. Molkenboer, G. Franssen, W. Van Weerden, W. Oyen, O. Boerman, October 2011, Journal of Nuclear Medicine, PubMed Link, DOI Link
Image quality phantom and parameters for high spatial resolution small-animal SPECT. E. Visser, A. Harteveld, A. Meeuwis, J. Disselhorst, F. Beekman, W. Oyen, O. Boerman, October 2011, Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, DOI Link
Quantitative multi-pinhole small-animal SPECT: Uniform versus non-uniform Chang attenuation correction. C. Wu, J. De Jong, H. Gratama Van Andel, F. Van Der Have, B. Vastenhouw, P. Laverman, O. Boerman, R. Dierckx, F. Beekman, September 2011, Physics in Medicine and Biology, PubMed Link, DOI Link
Radiolabeled cetuximab: Dose optimization for epidermal growth factor receptor imaging in a head-and-neck squamous cell carcinoma model. B. Hoeben, J. Molkenboer-Kuenen, W. Oyen, W. Peeters, J. Kaanders, J. Bussink, O. Boerman, August 2011, International Journal of Cancer, PubMed Link, DOI Link
99mtechnetium-HYNIC(tricine/TPPTS)-Aca-bombesin(7-14) as a targeted imaging agent with microSPECT in a PC-3 prostate cancer xenograft model. H. Ananias, Z. Yu, R. Dierckx, C. Van Der Wiele, W. Helfrich, F. Wang, Y. Yan, X. Chen, I. De Jong, P. Elsinga, August 2011, Molecular Pharmaceutics, PubMed Link, DOI Link
Fundamental limits of spatial resolution in PET. W. Moses, August 2011, Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, DOI Link
Review and current status of SPECT scatter correction. B. Hutton, I. Buvat, F. Beekman, 2011, Physics in Medicine and Biology, PubMed Link, DOI Link
An efficient simulator for pinhole imaging of PET isotopes. M. Goorden, F. Van Der Have, R. Kreuger, F. Beekman, March 2011, Physics in Medicine and Biology, PubMed Link, DOI Link
The effects of object activity distribution on multiplexing multi-pinhole SPECT. G. Mok, B. Tsui, F. Beekman, 2011, Physics in Medicine and Biology, PubMed Link, DOI Link
Targeted multi-pinhole SPECT. W. Branderhorst, B. Vastenhouw, F. Van Der Have, E. Blezer, W. Bleeker, F. Beekman, March 2011, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
Molecular SPECT Imaging: An Overview. M. Khalil, J. Tremoleda, T. Bayomy, W. Gsell, January 2011, International Journal of Molecular Imaging, PubMed Link, DOI Link

2010

Model-based measurements of the diameter of the internal carotid artery in CT angiography images. H. Gratama Van Andel, H. Venema, K. Bol, H. Marquering, C. Majoie, G. Den Heeten, C. Grimbergen, G. Streekstra, 2010, Medical Physics, PubMed Link, DOI Link
In vitro and in vivo evaluation of [99mTc]-labeled tricarbonyl His-annexin A5 as an imaging agent for the detection of phosphatidylserine-expressing cells. C. Vangestel, M. Peeters, R. Oltenfreiter, Y. D’Asseler, S. Staelens, M. Van Steenkiste, J. Philippé, D. Kusters, C. Reutelingsperger, N. Van Damme, C. Van de Wiele, November 2010, Nuclear Medicine and Biology, PubMed Link, DOI Link
Absolute quantitative total-body small-animal SPECT with focusing pinholes. C. Wu, F. Van Der Have, B. Vastenhouw, R. Dierckx, A. Paans, F. Beekman, November 2010, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
ImmunoSPECT and immunoPET of IGF-1R expression with the radiolabeled antibody R1507 in a triple-negative breast cancer model. S. Heskamp, H. Van Laarhoven, J. Molkenboer-Kuenen, G. Franssen, Y. Versleijen-Jonkers, W. Oyen, W. Van Der Graaf, O. Boerman, October 2010, Journal of Nuclear Medicine, PubMed Link, DOI Link
Measurement of porto-systemic shunting inmice by novel three-dimensionalmicro-single photon emission computed tomography imaging enabling longitudinal follow-up. C. Van Steenkiste, S. Staelens, S. Deleye, F. De Vos, S. Vandenberghe, A. Geerts, C. Van De Wiele, M. De Vos, H. Van Vlierberghe, I. Colle, September 2010, Liver International, PubMed Link, DOI Link
Hippocampal deep brain stimulation induces decreased rCBF in the hippocampal formation of the rat. T. Wyckhuys, S. Staelens, B. Van Nieuwenhuyse, S. Deleye, H. Hallez, K. Vonck, R. Raedt, W. Wadman, P. Boon, August 2010, NeuroImage, PubMed Link, DOI Link
Small-animal SPECT and SPECT/CT: Application in cardiovascular research. R. Golestani, C. Wu, R. Tio, C. Zeebregts, A. Petrov, F. Beekman, R. Dierckx, H. Boersma, R. Slart, August 2010, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter. S. De Bruyne, L. Wyffels, T. Boos, S. Staelens, S. Deleye, K. Rice, F. De Vos, May 2010, Nuclear Medicine and Biology, PubMed Link, DOI Link
Pixel-based subsets for rapid multi-pinhole SPECT reconstruction. W. Branderhorst, B. Vastenhouw, F. Beekman, April 2010, Physics in Medicine and Biology, PubMed Link, DOI Link
Evaluation of the radiation dose in micro-CT with optimization of the scan protocol. I. Willekens, N. Buls, T. Lahoutte, L. Baeyens, C. Vanhove, V. Caveliers, R. Deklerck, A. Bossuyt, J. De Mey, 2010, Contrast Media and Molecular Imaging, PubMed Link, DOI Link
Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer. L. Vervoort, I. Burvenich, S. Staelens, C. Dumolyn, E. Waegemans, M. Van Steenkiste, S. Baird, A. Scott, F. De Vos, April 2010, Cancer Biotherapy and Radiopharmaceuticals, PubMed Link, DOI Link
High-resolution tomography of positron emitters with clustered pinhole SPECT. M. Goorden, F. Beekman, March 2010, Physics in Medicine and Biology, PubMed Link, DOI Link
Accurate coregistration between ultra-high-resolution micro-SPECT and circular cone-beam micro-CT scanners. C. Ji, F. Van Der Have, H. Gratama Van Andel, R. Ramakers, F. Beekman, January 2010, International Journal of Biomedical Imaging, PubMed Link, DOI Link

2009

3-D rat brain phantom for high-resolution molecular imaging. F. Beekman, B. Vastenhouw, G. Van Der Wilt, M. Vervloet, R. Visscher, J. Booij, M. Gerrits, C. Ji, R. Ramakers, F. Van Der Have, December 2009, Proceedings of the IEEE, DOI Link
Effect of oblique X-ray incidence in flat-panel computed tomography of the breast. A. Badano, I. Kyprianou, M. Freed, R. Jennings, J. Sempau, December 2009, IEEE Transactions on Medical Imaging, PubMed Link, DOI Link
Theoretical analysis of full-ring multi-pinhole brain SPECT. M. Goorden, M. Rentmeester, F. Beekman, November 2009, Physics in Medicine and Biology, PubMed Link, DOI Link
Quantification of the multiplexing effects in multi-pinhole small animal SPECT: A simulation study. G. Mok, Y. Wang, B. Tsui, October 2009, IEEE Transactions on Nuclear Science, DOI Link
U-SPECT-II: An ultra-high-resolution device for molecular small-animal imaging. F. Van Have, B. Vastenhouw, R. Ramakers, W. Branderhorst, J. Krah, C. Ji, S. Staelens, F. Beekman, April 2009, Journal of Nuclear Medicine, PubMed Link, DOI Link
Ultra-high Resolution Imaging of PET tracers with clustered pinholes. M. Goorden, F. Beekman, 2009, 10th Fully 3D Meeting
Effect of cyclosporin A administration on the biodistribution and multipinhole μsPECT imaging of [123I]R91150 in rodent brain. P. Blanckaert, I. Burvenich, S. Staelens, S. De Bruyne, L. Moerman, L. Wyffels, F. De Vos, March 2009, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link

2008

Respiratory-gated CT as a tool for the simulation of breathing artifacts in PET and PET/CT. J. Hamill, G. Bosmans, A. Dekker, February 2008, Medical Physics, PubMed Link, DOI Link
System calibration and statistical image reconstruction for ultra-high resolution stationary pinhole SPECT. F. Van Der Have, B. Vastenhouw, M. Rentmeester, F. Beekman, January 2008, IEEE Transactions on Medical Imaging, PubMed Link, DOI Link

2007

Theoretical and Experimental Evaluation of Spatial Resolution in a Variable Resolution X-Ray Computed Tomography Scanner (Vol. , Issue December, pp. 1-206). R. Melnyk, December 2007
Movies of dopamine transporter occupancy with ultra-high resolution focusing pinhole SPECT. B. Vastenhouw, F. Van Der Have, A. Van Der Linden, L. Von Oerthel, J. Booij, J. Burbach, M. Smidt, F. Beekman, November 2007, Molecular Psychiatry, PubMed Link, DOI Link
Analysis of streak artefacts on CT images using statistics of extremes. K. Imai, M. Ikeda, S. Wada, Y. Enchi, T. Niimi, November 2007, The British Journal of Radiology, PubMed Link, DOI Link
Multi-modality imaging on track. F. Beekman, B. Hutton, September 2007, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link
Optimizing multi-pinhole SPECT geometries using an analytical model. M. Rentmeester, F. Van Der Have, F. Beekman, May 2007, Physics in Medicine and Biology, PubMed Link, DOI Link
Submillimeter total-body murine imaging with U-SPECT-I. B. Vastenhouw, F. Beekman, March 2007, Journal of Nuclear Medicine, PubMed Link
The pinhole: Gateway to ultra-high-resolution three-dimensional radionuclide imaging. F. Beekman, F. Van Der Have, February 2007, European Journal of Nuclear Medicine and Molecular Imaging, PubMed Link, DOI Link

2005

U-SPECT-I: A novel system for submillimeter-resolution tomography with radiolabeled molecules in mice. F. Beekman, F. Van Der Have, B. Vastenhouw, A. Van Der Linden, P. Van Rijk, J. Burbach, M. Smidt, July 2005, Journal of Nuclear Medicine, PubMed Link
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