In vivo diffuse optical imaging of small animals has been employed for over 20 years. In-spite of the advantages offered by optical imaging such as wide availability of optical reporters and probes, accurate in vivo optical imaging suffers from a major obstacle; light scattering in tissues. This results in strong signal attenuation and loss of directionality, making optical imaging unsuited for deep-tissue and high-resolution quantitative imaging. By using a new technique, called X-ray CT-guided Optical imaging, MILabs has been able to eliminate most of these shortcomings of in vivo optical imaging.In vivo diffuse optical imaging of small animals has been employed for over 20 years. In-spite of the advantages offered by optical imaging such as wide availability of optical reporters and probes, accurate in vivo optical imaging suffers from a major obstacle; light scattering in tissues. This results in strong signal attenuation and loss of directionality, making optical imaging unsuited for deep-tissue and high-resolution quantitative imaging. By using a new technique, called X-ray CT-guided Optical imaging, MILabs has been able to eliminate most of these shortcomings of in vivo optical imaging.
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