In-Vivo Optical Imaging: the coming of age of a technology

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After two decades of Optical Mouse Imaging, the technology is finally coming of age with new high-resolution quantitative 3D applications
In vivo diffuse optical imaging of small animals has been employed for over 20 years. In-spite of the advantages offered by optical imaging such as wide availability of optical reporters and probes, accurate in vivo optical imaging suffers from a major obstacle; light scattering in tissues. This results in strong signal attenuation and loss of directionality, making optical imaging unsuited for deep-tissue and high-resolution quantitative imaging.  

By using a new technique, called X-ray CT-guided Optical imaging, MILabs has been able to eliminate most of these shortcomings of in vivo optical imaging.In vivo diffuse optical imaging of small animals has been employed for over 20 years. In-spite of the advantages offered by optical imaging such as wide availability of optical reporters and probes, accurate in vivo optical imaging suffers from a major obstacle; light scattering in tissues.

This results in strong signal attenuation and loss of directionality, making optical imaging unsuited for deep-tissue and high-resolution quantitative imaging.  By using a new technique, called X-ray CT-guided Optical imaging, MILabs has been able to eliminate most of these shortcomings of in vivo optical imaging.

 
Since the introduction of MILabs’ Hybrid OI/CT system in 2018, many novel user applications for optical imaging have emerged. As illustrated above, the technology enhances translational in vivo imaging by providing quantitative 3D images. Please check out the following application examples on our website: Click here to learn more
The Dual-use Duet Optical Imaging Module complements MILabs’ bestselling line of upgradable systems
MILabs’ systems have a modular set up where PET, SPECT, Optical or CT functionality can be delivered separately or in any combination. After initial installation, additional functionalities and complete modules can be added to the platform. Moreover, by working in unison, combined modalities can achieve synergistic imaging capabilities. Learn more.
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