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Quantitative Multimodal Fluorescence and Bioluminescence Tomography with the MILabs OI-CT System

by Dr. Felix Gremse, RWTH Aachen University and Gremse IT

Hybrid fluorescence tomography and x-ray computed tomography (FLT-CT) provided by the MILabs OI-CT system allows non-invasive longitudinal volumetric assessment of fluorescent probes in mice in vivo. This talk demonstrates that FLT-CT can be used to quantitatively determine the biodistribution NIRF-labeled probes. It also demonstrates the functionality for multimodal bioluminescence tomography (BLT-CT) which uses multispectral images to identify deep luminescent sources such as luciferase-expressing tumors and metastases.

Took place: August, 2020 (at vEMIM)

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