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Selected VECTor and U-SPECT articles
(technology and applications):

In the article links below you can find more information on technical back ground and applications of MILabs´ proprietary multi-pinhole technologies for ultra-high resolution radionuclide imaging.

Varenicline increases in vivo striatal dopamine D(2/3) receptor binding: an ultra-high-resolution pinhole [(123)I]IBZM SPECT study in rats. Crunelle et al. Nucl Med Biol. Direct link
Murine cardiac images obtained with focusing pinhole SPECT are barely influenced by extra-cardiac activity. Branderhorst et al. Phys Med Biol. Direct link
Imaging of Human Epidermal Growth Factor Receptor Type 2 Expression with 18F-Labeled Affibody Molecule ZHER2:2395 in a Mouse Model for Ovarian Cancer. Heskamp et al. J Nucl Med. Direct link
Predicting IGF-1R Therapy Response in Bone Sarcomas: Immuno-SPECT Imaging with Radiolabeled R1507. Fleuren et al. Clin Cancer Res. Direct link
Imaging of Prostate Cancer with Immuno-PET and Immuno-SPECT Using a Radiolabeled Anti-EGP-1 Monoclonal Antibody. van Rij et al. J. Nucl Med. Direct link
99mTc-(CO)3 His-Annexin A5 Micro-SPECT Demonstrates Increased Cell Death by Irinotecan During the Vascular Normalization Window Caused by Bevacizumab. Vangestel et al. J. Nucl Med. Direct link
Single-Photon Emission Computed Tomographic Imaging of the Early Time Course of Therapy-Induced Cell Death Using Technetium 99m Tricarbonyl His-Annexin A5 in a Colorectal Cancer Xenograft Model. Vangestel et al. Mol Imaging. Direct link
Quantitative multi-pinhole small-animal SPECT: uniform vs. non-uniform Chang attenuation correction. Wu et al. Phys Med Biol. Direct link
Image quality phantom and parameters for high spatial resolution small-animal SPECT. Visser et al. Nucl. Instr. and Meth. Direct link
Hippocampal deep brain stimulation induces decreased rCBF in the hippocampal formation of the rat. Wyckhuys et al. NeuroImage. Pubmed Link
Absolute quantitative total-body small-animal SPECT with focusing pinholes. Wu et al. EJNM & Mol. Im. Pubmed link
Measurement of porto-systemic shunting in mice by novel three-dimensionalmicro-single photon emission computed tomography imaging enabling longitudinal follow-up. Steenkiste et al. LiverInt. Pubmed link
Accurate coregistration between Ultra-High-Resolution micro-SPECT and circular Cone-beam micro-CT scanners. Ji et al. Int. J. Biomed. Imaging. Pubmed link
Radiolabeled cetuximab Dose optimization for EGFR imaging in a head-and-neck squamous cell carcinoma model. Hoeben et al. Int. J. Cancer. Pubmed link
Pixel-based subsets for rapid multi-pinhole SPECT reconstruction. Branderhorst et al. Phys Med Biol. Direct link
ImmunoSPECT and ImmunoPET in IGF-1R Expression with the radiolabeled antibody R1507 in a triple-negative breast cancer model. Heskamp et al. J. Nucl. Med. Pubmed link
High-resolution tomography of positron emitters with clustered pinhole SPECT. Goorden et al. Phys. Med Biol. Pubmed link
Small-animal SPECT and SPECT/CT application in cardiavascular research. Golestani et al. Eur J Nucl Med Mol. Im. Pubmed link
In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter. Bruyne et al. Nucl .Med. Bio. Pubmed link